Anna Bulek

Autolus (United Kingdom) — United Kingdom

Immunology and Microbiology · Life Sciences

19h-index1.3kcitations39works9.52yr avg
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Research Topics

Immune Cell Function and Interaction(24), T-cell and B-cell Immunology(19), CAR-T cell therapy research(12), Monoclonal and Polyclonal Antibodies Research(11), Immunotherapy and Immune Responses(8)

Publications39 total

CAR T cell therapy selectively depletes disease-driving mutant calreticulin cells in xenotransplants and human organoid models of myelofibrosis
2026Open Access
HLA A*24:02–restricted T cell receptors cross-recognize bacterial and preproinsulin peptides in type 1 diabetes
Journal of Clinical Investigation·2024· 8 citedOpen Access
Structure-guided engineering of immunotherapies targeting TRBC1 and TRBC2 in T cell malignancies
Nature Communications·2024· 23 citedOpen Access
Designer Small-Molecule Control System Based on Minocycline-Induced Disruption of Protein–Protein Interaction
ACS Chemical Biology·2024· 7 citedOpen Access
Dual targeting of CD19 and CD22 against B-ALL using a novel high-sensitivity aCD22 CAR
Molecular Therapy·2023· 1 citedOpen Access
Designer small molecule control system based on Minocycline induced disruption of protein-protein interaction
2023· 1 citedOpen Access
Exploration of T cell immune responses by expression of a dominant-negative SHP1 and SHP2
Frontiers in Immunology·2023· 6 citedOpen Access
Exploration of T-cell immune responses by expression of a dominant-negative SHP1 and SHP2
2023Open Access
Dual targeting of CD19 and CD22 against B-ALL using a novel high-sensitivity aCD22 CAR
Molecular Therapy·2023· 31 citedOpen Access
Structure-Guided Engineering of Immunotherapies Targeting TRBC1 and TRBC2 in T Cell Malignancies
2022· 5 citedOpen Access
TCR‐induced alteration of primary MHC peptide anchor residue
European Journal of Immunology·2019· 28 citedOpen Access
Author response for "TCR‐induced alteration of primary MHC peptide anchor residue"
2019
Structure Guided Engineering of Highly Specific Chimeric Antigen Receptors for the Treatment of T Cell Lymphomas
Blood·2018· 10 cited
In Silico and Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility
Frontiers in Immunology·2018· 25 citedOpen Access
Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope
Frontiers in Immunology·2017· 29 citedOpen Access
T cell receptor alpha variable 12‐2 bias in the immunodominant response to Yellow fever virus
European Journal of Immunology·2017· 38 citedOpen Access
Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase
Journal of Biological Chemistry·2016· 29 citedOpen Access
Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity
Journal of Clinical Investigation·2016· 30 citedOpen Access
Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity
Journal of Clinical Investigation·2016· 158 citedOpen Access
A Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen
Journal of Biological Chemistry·2016· 34 citedOpen Access
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Frequent Co-authors

Andrew K. Sewell(29), David K. Cole(27), P.J. Rizkallah(24), Anna Fuller(15), Garry Dolton(10), John J. Miles(10), Andrea J. Schauenburg(10), Mathieu Ferrari(9), Isaac Gannon(9), Martin Pulé(9), Florian Madura(8), Linda Wooldridge(7), James Sillibourne(7), Shimobi Onuoha(7), Shaun Cordoba(7), Simon Thomas(7), Mark Peakman(6), Christopher Holland(6), Ram Jha(6), Vania Baldan(6)