Scott G. Filler

Foundation for Biomedical Research — United States

Medicine · Health Sciences

86h-index27.7kcitations325works6.72yr avg
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Research Topics

Antifungal resistance and susceptibility(244), Fungal Infections and Studies(147), Peptidase Inhibition and Analysis(31), Pneumocystis jirovecii pneumonia detection and treatment(25), Neutrophil, Myeloperoxidase and Oxidative Mechanisms(21)

Publications323 total

The HosA histone deacetylase regulates stress resistance, host cell interactions, and virulence in <i>Aspergillus fumigatus</i>
2025Open Access
Metabolic imprinting drives epithelial memory during mucosal fungal infection
2025Open Access
Strain background interacts with chromosome 7 aneuploidy to determine commensal and virulence phenotypes in Candida albicans
PLoS Genetics·2025· 2 citedOpen Access
Host targets of candidalysin
PLoS Pathogens·2025· 1 citedOpen Access
A humanized antibody against mucormycosis targets angioinvasion and augments the host immune response
Science Translational Medicine·2025· 6 cited
Fungal Als proteins hijack host death effector domains to promote inflammasome signaling
Nature Communications·2025· 4 citedOpen Access
Strain background interacts with chromosome 7 aneuploidy to determine commensal and virulence phenotypes in <i>Candida albicans</i>
2025Open Access
Epidermal growth factor receptor signaling governs the host inflammatory response to invasive aspergillosis
mBio·2024· 5 citedOpen Access
Sulfated glycosaminoglycans are host epithelial cell targets of the Candida albicans toxin candidalysin
Nature Microbiology·2024· 16 citedOpen Access
Non-canonical IL-22 receptor signaling remodels the mucosal barrier during fungal immunosurveillance
2024· 3 citedOpen Access
Epidermal Growth Factor Receptor Signaling Governs the Host Inflammatory Response to Invasive Aspergillosis
2024· 1 citedOpen Access
Single-cell detection of copy number changes reveals dynamic mechanisms of adaptation to antifungals in Candida albicans
Nature Microbiology·2024· 25 citedOpen Access
Step-wise evolution of azole resistance through copy number variation followed by KSR1 loss of heterozygosity in Candida albicans
PLoS Pathogens·2024· 17 citedOpen Access
Aspergillus fumigatus conidial surface-associated proteome reveals factors for fungal evasion and host immunity modulation
Nature Microbiology·2024· 19 citedOpen Access
Erg251 has complex and pleiotropic effects on sterol composition, azole susceptibility, filamentation, and stress response phenotypes
PLoS Pathogens·2024· 12 citedOpen Access
A Brg1-Rme1 circuit in <i>Candida albicans</i> hyphal gene regulation
mBio·2024· 5 citedOpen Access
A genome-scale screen identifies sulfated glycosaminoglycans as pivotal in epithelial cell damage by <i>Candida albicans</i>
2024· 1 citedOpen Access
Hyphal Als proteins act as CR3 ligands to promote immune responses against Candida albicans
Nature Communications·2024· 13 citedOpen Access
Tensor modeling of MRSA bacteremia cytokine and transcriptional patterns reveals coordinated, outcome-associated immunological programs
PNAS Nexus·2024· 5 citedOpen Access
Ibrexafungerp is efficacious in a neutropenic murine model of pulmonary mucormycosis as monotherapy and combined with liposomal amphotericin B
Antimicrobial Agents and Chemotherapy·2024· 8 citedOpen Access
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Frequent Co-authors

John E. Edwards(18), Ashraf S. Ibrahim(14), Donald C. Sheppard(11), Quynh T. Phan(9), Michael R. Yeaman(8), Norma V. Solis(8), Yue Fu(6), Aaron P. Mitchell(5), Brad Spellberg(5), Vincent M. Bruno(5), Peter G. Pappas(4), Carter L. Myers(4), Michail S. Lionakis(4), Fabrice N. Gravelat(4), David R. Andes(3), Thomas J. Walsh(3), Clarissa J. Nobile(3), Yue Fu(3), Bernhard Hube(3), Hong Liu(3)