Ian J. Donaldson

Donaldson (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

30h-index3.1kcitations78works1.62yr avg
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Research Topics

Genomics and Chromatin Dynamics(22), RNA Research and Splicing(10), CRISPR and Genetic Engineering(8), Developmental Biology and Gene Regulation(6), Epigenetics and DNA Methylation(6)

Publications78 total

Human pluripotent stem cell model of multiple epiphyseal dysplasia with MATN3 mutation identifies altered matrix organisation and upregulation of the cholesterol biosynthesis pathway
Osteoarthritis and Cartilage·2026Open Access
322 Single-cell RNA sequencing of afamitresgene autoleucel indicates mechanisms of persistence and anti-tumor activity
Regular and Young Investigator Award Abstracts·2025Open Access
Construction of a reference genome for <i>Starmerella batistae</i> and annotation of <i>Starmerella</i> species reveal a close evolutionary relationship with <i>Schizosaccharomyces pombe</i> and suggest an alternative pathway for sophorolipid production.
2025Open Access
Epigenome and transcriptome changes in KMT2D-related Kabuki syndrome Type 1 iPSCs, neuronal progenitors and cortical neurons
PLoS Genetics·2025· 2 citedOpen Access
Human pluripotent stem cell model of multiple epiphyseal dysplasia with <i>MATN3</i> mutation identifies altered Matrix organisation and upregulation of the cholesterol biosynthesis pathway
2025Open Access
PNUTS:PP1 recruitment to Tox4 regulates chromosomal dispersal in Drosophila germline development
Cell Reports·2025Open Access
Ubiquitous MEIS transcription factors actuate lineage-specific transcription to establish cell fate
The EMBO Journal·2025· 2 citedOpen Access
Epigenome and transcriptome changes in <i>KMT2D</i> -related Kabuki syndrome Type 1 iPSCs, neuronal progenitors and cortical neurons
2025Open Access
Abstract A017: HER2 overexpression initiates breast tumorigenesis non-cell-autonomously by altering energy metabolism in the tissue microenvironment
Cancer Research·2024
Preclinical Proof of Concept for Decentralized Manufacturing of a MAGE-A4/CD8α-Expressing Autologous T-Cell Therapy for Solid Tumors
Blood·2024· 1 citedOpen Access
Integrated multi-omics analysis of PBX1 in mouse adult neural stem- and progenitor cells identifies a transcriptional module that functionally links PBX1 to TCF3/4
Nucleic Acids Research·2024· 5 citedOpen Access
318 (PB306): HER2 overexpression initiates breast tumorigenesis non-cellautonomously by inducing oxidative stress in the tissue microenvironment
European Journal of Cancer·2024
The evolutionary ancient MEIS transcription factors actuate lineage-specific transcription to establish cardiac fate
2024· 2 citedOpen Access
Cardiac GR Mediates the Diurnal Rhythm in Ventricular Arrhythmia Susceptibility
Circulation Research·2024· 12 citedOpen Access
Abstract 3380: HER2 overexpression induces breast tumorigenesis in a non cell autonomous manner by inducing oxidative stress in the tissue microenvironment
Cancer Research·2024
PAK1-dependent mechanotransduction enables myofibroblast nuclear adaptation and chromatin organization during fibrosis
Cell Reports·2023· 17 citedOpen Access
HER2 overexpression initiates breast tumorigenesis non-cell-autonomously by inducing oxidative stress in the tissue microenvironment
2023Open Access
Circadian Disruption Primes Myofibroblasts for Accelerated Activation as a Mechanism Underpinning Fibrotic Progression in Non-Alcoholic Fatty Liver Disease
Cells·2023· 14 citedOpen Access
PAK1-dependant mechanotransduction enables myofibroblast nuclear adaptation and chromatin organisation during fibrosis
2023· 2 citedOpen Access
<i>Aspergillus fumigatus</i> Can Display Persistence to the Fungicidal Drug Voriconazole
Microbiology Spectrum·2023· 18 citedOpen Access
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Frequent Co-authors

Berthold Göttgens(18), Anthony R. Green(9), Leo Zeef(7), Sarah Kinston(7), Nicoletta Bobola(6), Kathy Knezevic(5), Michael A. Chapman(4), Andrew D Sharrocks(4), Sandie Piltz(4), George Follows(4), John E. Pimanda(3), Magnus Rattray(3), Franck Ladam(3), Charles G. Sagerström(3), Andrew Hayes(3), David Ray(3), Daniela Delneri(3), Karen Piper Hanley(3), Neil A. Hanley(3), Alexander W. Bruce(2)