Eva K. Brinkman

Science for Life Laboratory — Sweden

Biochemistry, Genetics and Molecular Biology · Life Sciences

9h-index4.0kcitations20works0.02yr avg
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Research Topics

CRISPR and Genetic Engineering(13), DNA Repair Mechanisms(8), Genomics and Chromatin Dynamics(5), Chromosomal and Genetic Variations(4), RNA and protein synthesis mechanisms(4)

Publications20 total

Intrinsic deletion at 10q23.31, including the <i>PTEN</i> gene locus, is aggravated upon CRISPR-Cas9–mediated genome engineering in HAP1 cells mimicking cancer profiles
Life Science Alliance·2023· 2 citedOpen Access
S154: IDENTIFICATION OF NOVEL FACTORS CONTROLLING NON GENETIC CELL PLASTICITY IN CHRONIC MYELOID LEUKEMIA
HemaSphere·2023Open Access
CRISPR-Cas9-mediated genome engineering exaggerates genomic deletion at 10q23.31 including the <i>PTEN</i> gene locus mimicking cancer profiles
2023Open Access
Protocol: A Multiplexed Reporter Assay to Study Effects of Chromatin Context on DNA Double-Strand Break Repair
Frontiers in Genetics·2022· 7 citedOpen Access
Impact of chromatin context on Cas9-induced DNA double-strand break repair pathway balance
Molecular Cell·2021· 201 citedOpen Access
Rapid Quantitative Evaluation of CRISPR Genome Editing by TIDE and TIDER v1
2020Open Access
Impact of chromatin context on Cas9-induced DNA double-strand break repair pathway balance
2020· 26 citedOpen Access
Ride the Tide: Observing CRISPR/Cas9 genome editing by the numbers
RePub (Erasmus University, Rotterdam)·2019· 1 citedOpen Access
Rapid Quantitative Evaluation of CRISPR Genome Editing by TIDE and TIDER
Methods in molecular biology·2019· 158 citedOpen Access
Mapping 3D genome organization relative to nuclear compartments using TSA-Seq as a cytological ruler
The Journal of Cell Biology·2018· 457 citedOpen Access
Kinetics and Fidelity of the Repair of Cas9-Induced Double-Strand DNA Breaks
Molecular Cell·2018· 288 citedOpen Access
TSA-Seq Mapping of Nuclear Genome Organization
2018· 7 citedOpen Access
Easy quantification of template-directed CRISPR/Cas9 editing
Nucleic Acids Research·2018· 197 citedOpen Access
Easy quantification of template-directed CRISPR/Cas9 editing
2017· 25 citedOpen Access
Quantitative analysis shows that repair of Cas9-induced double-strand DNA breaks is slow and error-prone
2017· 1 citedOpen Access
A single double-strand break system reveals repair dynamics and mechanisms in heterochromatin and euchromatin
Genes & Development·2016· 114 citedOpen Access
Easy quantitative assessment of genome editing by sequence trace decomposition
Nucleic Acids Research·2014· 2.5k citedOpen Access
UV-induced G2 checkpoint depends on p38 MAPK and minimal activation of ATR-Chk1 pathway
Journal of Cell Science·2013· 9 citedOpen Access
A Toolkit to Enable Hydrocarbon Conversion in Aqueous Environments
Journal of Visualized Experiments·2012· 1 citedOpen Access
A Toolkit to Enable Hydrocarbon Conversion in Aqueous Environments
Journal of Visualized Experiments·2012· 1 cited

Frequent Co-authors

Bas van Steensel(13), Tao Chen(5), Christ Leemans(5), Ruben Schep(3), Tom van Schaik(3), René H. Medema(3), Yu Chen(2), Yang Zhang(2), Yuchuan Wang(2), Liguo Zhang(2), Stephen A. Adam(2), Robert D. Goldman(2), Jian Ma(2), Andrew S. Belmont(2), Marcel de Haas(2), Hanna A. Holland(2), Waseem Akhtar(2), Xabier Vergara(2), Ben Morris(2), Stefano Giustino Manzo(2)