Rocío Ruiz

Instituto de Biomedicina de Sevilla — Spain

Neuroscience · Life Sciences

25h-index2.6kcitations79works8.02yr avg
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Research Topics

Neuroinflammation and Neurodegeneration Mechanisms(15), Neuroscience and Neuropharmacology Research(9), Cellular transport and secretion(9), Genetics and Neurodevelopmental Disorders(9), Neurogenetic and Muscular Disorders Research(9)

Publications79 total

Metabolic and transcriptional adaptations to phagocytosis sustain microglia functionality and regenerative properties
2025Open Access
Metabolic and transcriptional adaptations to phagocytosis sustain microglia functionality and regenerative properties
2025· 1 cited
Drug screening targeting TREM2-TYROBP transmembrane binding
Molecular Medicine·2025· 3 citedOpen Access
HERC1 E3 Ubiquitin Ligase Is Necessary for Autophagy Processes and for the Maintenance and Homeostasis of Vesicles in Motor Nerve Terminals, but Not for Proteasomal Activity
International Journal of Molecular Sciences·2025· 1 citedOpen Access
Drug screening targeting TREM2-TYROBP transmembrane binding
2024Open Access
Dopaminergic neurons lacking Caspase-3 avoid apoptosis but undergo necrosis after MPTP treatment inducing a Galectin-3-dependent selective microglial phagocytic response
Cell Death and Disease·2024· 16 citedOpen Access
Nerve Injury Triggers Time-dependent Activation of the Locus Coeruleus, Influencing Spontaneous Pain-like Behavior in Rats
Anesthesiology·2024· 4 citedOpen Access
Inflammatory bowel disease induces pathological α‐synuclein aggregation in the human gut and brain
Neuropathology and Applied Neurobiology·2024· 39 citedOpen Access
Author response for "Inflammatory bowel disease induces pathological α‐synuclein aggregation in the human gut and brain"
2023
GALECTIN-3 SHAPES TOXIC ALPHA-SYNUCLEIN AGGREGATES IN PARKINSON´S DISEASE
IBRO Neuroscience Reports·2023· 1 citedOpen Access
TARGETING GALECTIN-3 TO COUNTERACT SPIKE-PHASE UNCOUPLING OF FAST-SPIKING INTERNEURONS TO GAMMA OSCILLATIONS IN ALZHEIMER'S DISEASE
IBRO Neuroscience Reports·2023· 2 citedOpen Access
HERC1 IS NECESSARY FOR AUTOPHAGY PROCESSES AND FOR THE MAINTENANCE AND HOMEOSTASIS OF VESICLES IN THE NEUROMUSCULAR JUNCTION, BUT NOT FOR THE PROTEASOMAL ACTIVITY.
IBRO Neuroscience Reports·2023Open Access
Author response for "Inflammatory bowel disease induces pathological α‐synuclein aggregation in the human gut and brain"
2023
Caecum OX40+CD4 T-cell subset associates with mucosal damage and key markers of disease in treated HIV-infection
Journal of Microbiology Immunology and Infection·2023· 1 citedOpen Access
A metagenome-wide association study of HIV disease progression in HIV controllers
iScience·2023· 4 citedOpen Access
Microglial Caspase-3 is essential for modulating hippocampal neurogenesis
Brain Behavior and Immunity·2023· 14 citedOpen Access
Galectin-3 shapes toxic alpha-synuclein strains in Parkinson’s disease
Acta Neuropathologica·2023· 34 citedOpen Access
ARG1-expressing microglia show a distinct molecular signature and modulate postnatal development and function of the mouse brain
Nature Neuroscience·2023· 84 citedOpen Access
Correction to: Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer’s disease
Acta Neuropathologica·2023· 2 citedOpen Access
Targeting galectin-3 to counteract spike-phase uncoupling of fast-spiking interneurons to gamma oscillations in Alzheimer’s disease
Translational Neurodegeneration·2023· 18 citedOpen Access
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Frequent Co-authors

Lucı́a Tabares(17), José L. Venero(16), Eva M. Pérez-Villegas(13), José Á. Armengol(12), Juan García‐Revilla(11), Luís Miguel Real(10), Ana M. Espinosa‐Oliva(10), Tomas Deierborg(9), Sara Bachiller(9), Irene García-Domínguez(8), Antonio Boza‐Serrano(6), María Angustias Roca-Ceballos(6), Agustı́n Ruiz(6), Bertrand Joseph(6), Isabel M. Alonso-Bellido(6), Marti Santiago(6), Raquel Cano(5), Rocío M. de Pablos(5), Ángel Manuel Carrión(5), José Luís Rosa(5)