Heike L. Pahl

University of Freiburg — Germany

Medicine · Health Sciences

54h-index19.9kcitations239works4.82yr avg
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Research Topics

Myeloproliferative Neoplasms: Diagnosis and Treatment(111), Acute Myeloid Leukemia Research(54), Chronic Myeloid Leukemia Treatments(49), Eosinophilic Disorders and Syndromes(44), Kruppel-like factors research(40)

Publications239 total

Minimal residual disease (MRD)-negative outcomes following a novel, in vivo gene therapy generating anti–B-cell maturation antigen (BCMA) chimeric antigen receptor (CAR)-T cells in patients with relapsed and refractory multiple myeloma (RRMM): Preliminary results from inMMyCAR, the first-in-human phase 1 study of KLN-1010
Blood·2025· 3 cited
MPN with multiple driver clones show distinct patterns of therapy response and progression - “MPN double driver”
Blood·2025Open Access
The PDI-ATF6-axis as a novel treatment target in CSF3R driven chronic neutrophilic leukemia (CNL)
Blood·2025
Response to PD-1 inhibition in MMRd/MSS pancreatic ductal adenocarcinoma: the relevance of parallel testing
Journal of Cancer Research and Clinical Oncology·2025Open Access
Lysine-specific demethylase 1 regulates hematopoietic stem cell expansion and myeloid cell differentiation
Cell Death and Disease·2025· 1 citedOpen Access
Final Results From a Large, Non‐Interventional, Phase 4 Study of Ruxolitinib for the Treatment of Myelofibrosis in Clinical Routine
European Journal Of Haematology·2025Open Access
Malignant JAK-signaling: at the interface of inflammation and malignant transformation
Leukemia·2025· 31 citedOpen Access
CSF3RT618I Is Stabilized By Calnexin and Induces Unfolded Protein Response (UPR) and ER-Phagy: A Pro-Survival Pathway for Oncogenic Misfolded CSF3R Proteins in Chronic Neutrophilic Leukemia (CNL)
Blood·2024
Supplementary Data from Oncogenic Calreticulin Induces Immune Escape by Stimulating TGFβ Expression and Regulatory T-cell Expansion in the Bone Marrow Microenvironment
2024Open Access
Data from Oncogenic Calreticulin Induces Immune Escape by Stimulating TGFβ Expression and Regulatory T-cell Expansion in the Bone Marrow Microenvironment
2024Open Access
Supplementary Data from Oncogenic Calreticulin Induces Immune Escape by Stimulating TGFβ Expression and Regulatory T-cell Expansion in the Bone Marrow Microenvironment
2024Open Access
Data from Oncogenic Calreticulin Induces Immune Escape by Stimulating TGFβ Expression and Regulatory T-cell Expansion in the Bone Marrow Microenvironment
2024Open Access
Oncogene-induced TIM-3 ligand expression dictates susceptibility to anti–TIM-3 therapy in mice
Journal of Clinical Investigation·2024· 17 citedOpen Access
Oncogenic Calreticulin Induces Immune Escape by Stimulating TGFβ Expression and Regulatory T-cell Expansion in the Bone Marrow Microenvironment
Cancer Research·2024· 15 citedOpen Access
GPRC5C drives branched-chain amino acid metabolism in leukemogenesis
Repository for Publications and Research Data (ETH Zurich)·2023Open Access
Real-world analysis of ruxolitinib in myelofibrosis: interim results focusing on patients who were naïve to JAK inhibitor therapy treated within the JAKoMo non-interventional, phase IV trial
Annals of Hematology·2023· 10 citedOpen Access
GPRC5C drives branched-chain amino acid metabolism in leukemogenesis
Blood Advances·2023· 19 citedOpen Access
The histone demethylase JMJD2C constitutes a novel NFE2 target gene that is required for the survival of JAK2V617F mutated cells
Leukemia·2023· 6 citedOpen Access
New C3H KitN824K/WT cancer mouse model develops late-onset malignant mammary tumors with high penetrance
Scientific Reports·2022· 2 citedOpen Access
New C3H <i>Kit</i> <sup>N824K/WT</sup> cancer mouse model develops late-onset malignant mammary tumors with high penetrance
2022· 1 citedOpen Access
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Frequent Co-authors

Patrick A. Baeuerle(8), Irmgard Merfort(7), Thomas J. Schmidt(5), Jonas S. Jutzi(5), Guido Lyß(4), Jean‐Jacques Kiladjian(4), Martin Grießhammer(4), Tiziano Barbui(4), Alessandro M. Vannucchi(4), Elisabeth Strunck(4), Torsten Loop(3), E. Britta-Mareen Traenckner(3), Frank Stegelmann(3), Andreas Reiter(3), Claire Harrison(3), Francisco Cervantes(3), Peter Johansson(3), Giovanni Barosi(3), Björn Andréasson(3), Alessandro Rambaldi(3)