Rachelle Buchanan

Immunology and Microbiology · Life Sciences

13h-index558citations27works4.32yr avg
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Research Topics

Immune Response and Inflammation(10), Immunotherapy and Immune Responses(8), T-cell and B-cell Immunology(6), COVID-19 Clinical Research Studies(5), SARS-CoV-2 and COVID-19 Research(5)

Publications27 total

Fusion protein pan-sarbecovirus vaccines elicit broadly protective immune responses targeting Clade 1a, 1b, and 3 sarbecoviruses
2026Open Access
Safety and immunogenicity of COVAC-2, a Sepivac SWE™ adjuvanted SARS-CoV-2 recombinant protein vaccine in healthy adults; a randomized controlled first-in-human dose-escalation trial
Vaccine·2025· 2 citedOpen Access
PASC (Post Acute Sequelae of COVID-19) is associated with decreased neutralizing antibody titers in both biological sexes and increased ANG-2 and GM-CSF in females
Scientific Reports·2024· 11 citedOpen Access
PASC (Post Acute Sequelae of COVID-19) is associated with decreased neutralizing antibody titers and increased inflammatory cytokines
Research Square (Research Square)·2023Open Access
Previous infection with seasonal coronaviruses does not protect male Syrian hamsters from challenge with SARS-CoV-2
Nature Communications·2023· 8 citedOpen Access
Third COVID-19 vaccine dose boosts antibody function in Rwandans with high HIV viral load
iScience·2023· 3 citedOpen Access
Signatures of Original Antigenic Sin or protection following coronavirus imprinting in Syrian hamsters challenged with SARS-CoV-2 or variants
2023Open Access
Co-stimulation by TLR7/8 ligand R848 modulates IFN-γ production of porcine γδ T cells in a microenvironment-dependent manner
Developmental & Comparative Immunology·2022· 3 cited
Assessing the <i>In Vivo</i> Effectiveness of Cationic Lipid Nanoparticles with a Triple Adjuvant for Intranasal Vaccination against the Respiratory Pathogen <i>Bordetella pertussis</i>
Molecular Pharmaceutics·2022· 12 cited
Oral antigen exposure in newborn piglets circumvents induction of oral tolerance in response to intraperitoneal vaccination in later life
BMC Veterinary Research·2015· 5 citedOpen Access
Oral antigen exposure in extreme early life in lambs influences the magnitude of the immune response which can be generated in later life
BMC Veterinary Research·2013· 13 citedOpen Access
Porcine Neonatal Blood Dendritic Cells, but Not Monocytes, Are More Responsive to TLRs Stimulation than Their Adult Counterparts
PLoS ONE·2013· 27 citedOpen Access
Low Dose Antigen Exposure for a Finite Period in Newborn Rats Prevents Induction of Mucosal Tolerance
PLoS ONE·2012· 13 citedOpen Access
Innate Immune Cocktail Partially Protects Broilers Against Cellulitis and Septicemia
Avian Diseases·2012· 7 cited
Innate Immune Cocktail Partially Protects Broilers Against Cellulitis and Septicemia
Avian Diseases Digest·2012
Interferon-gamma and B-cell Activating Factor (BAFF) promote bovine B cell activation independent of TLR9 and T-cell signaling
Veterinary Immunology and Immunopathology·2012· 8 cited
Milk-derived antimicrobial peptides to protect against Neonatal Diarrheal Disease: An alternative to antibiotics
Procedia in Vaccinology·2012· 10 citedOpen Access
Influence of maternal antibodies on active pertussis toxoid immunization of neonatal mice and piglets
Vaccine·2011· 40 cited
Stability of expression of reference genes in porcine peripheral blood mononuclear and dendritic cells
Veterinary Immunology and Immunopathology·2011· 34 cited
B-cell activating factor (BAFF) promotes CpG ODN-induced B cell activation and proliferation
Cellular Immunology·2011· 16 cited
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Frequent Co-authors

Volker Gerdts(19), Lorne A. Babiuk(11), Heather L. Wilson(10), Jill van Kessel(6), Brittany Thivierge(6), Darryl Falzarano(6), Alyson A. Kelvin(6), Magen E. Francis(5), Joseph Darbellay(5), Cynthia L. Swan(5), J. Lew(5), Marina Facci(4), Gaël Auray(4), George Mutwiri(4), Ethan B. Jansen(4), Erin Scruten(4), Anthony Yourkowski(4), Shokrollah Elahi(3), Scott A. Halperin(3), Andrew Potter(3)