Shih‐Chan Lai

Chung Shan Medical University Hospital — Taiwan

Agricultural and Biological Sciences · Life Sciences

20h-index1.1kcitations69works1.22yr avg
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Research Topics

Mollusks and Parasites Studies(45), Parasite Biology and Host Interactions(25), Parasitic infections in humans and animals(11), Helminth infection and control(8), Toxoplasma gondii Research Studies(8)

Publications69 total

COX-2/PGE₂ signaling drives Toxocara canis-induced lung pathology by enhancing plasminogen activator activity and collagen VI degradation
Scientific Reports·2025Open Access
CX3CL1/CX3CR1 involved modulation of microglial activation and eosinophilic meningoencephalitis in angiostrongyliasis
Food and Waterborne Parasitology·2025· 1 citedOpen Access
Upregulation of Nrf2 attenuates Angiostrongylus cantonensis-induced parasitic meningitis in mice
Parasites & Vectors·2025Open Access
Activation of the COX-2/mPGES-1/PGE-2 cascade through the NLRP3 inflammasome contributes to Angiostrongylus cantonensis-induced eosinophilic meningoencephalitis
Parasitology Research·2025Open Access
Suppressing DUSP16 overexpression induced by ELK1 promotes neural progenitor cell differentiation in mouse models of Alzheimer's disease
Aging Cell·2024· 2 citedOpen Access
Neuroprotective effects of CysLT2R antagonist on Angiostrongylus cantonensis-induced edema and meningoencephalitis
Molecular and Biochemical Parasitology·2024· 2 cited
Activation of the COX-2/mPGES-1/PGE-2 cascade through the NLRP3 inflammasome contributes to Angiostrongylus cantonensis-induced eosinophilic meningoencephalitis
2024Open Access
Curative effects and mechanisms of AG1296 and LY294002 co-therapy in Angiostrongylus cantonensis-induced neurovascular unit dysfunction and eosinophilic meningoencephalitis
Journal of Microbiology Immunology and Infection·2024· 1 citedOpen Access
Exploration of the Molecular Mechanism by Which Caveolin-1 Regulates Changes in Blood–Brain Barrier Permeability Leading to Eosinophilic Meningoencephalitis
Tropical Medicine and Infectious Disease·2024· 5 citedOpen Access
Explore the Molecular Mechanism of Caveolae-1 Regulates Changes in Blood-Brain Barrier Permeability Leading to Eosinophilic Meningoencephalitis
Preprints.org·2024· 1 citedOpen Access
Neuroprotective effects of CysLT2R antagonist on Angiostrongylus cantonensis-induced edema and meningoencephalitis
2023· 1 citedOpen Access
Calycosin attenuates<i>Angiostrongylus cantonensis</i>-induced parasitic meningitis through modulation of HO-1 and NF-<i>κ</i>B activation
Parasitology·2022· 6 citedOpen Access
Heme oxygenase-1 modulates brain inflammation and apoptosis in mice with angiostrongyliasis
Parasitology International·2021· 9 cited
Peroxisome-Proliferator Activator Receptor γ in Mouse Model with Meningoencephalitis Caused by Angiostrongylus cantonensis
Journal of Parasitology·2021· 4 cited
Regulation of Proinflammatory Enzymes by Peroxisome Proliferator–Activated Receptor Gamma in Astroglia Infected with Toxoplasma gondii
Journal of Parasitology·2020· 5 cited
Angiostrongylus cantonensis infection induces MMP-9 and causes tight junction protein disruption associated with Purkinje cell degeneration
Parasitology Research·2020· 5 cited
Matrix metalloproteinases activation in Toxocara canis induced pulmonary pathogenesis
Journal of Microbiology Immunology and Infection·2020· 11 citedOpen Access
Proteasome serves as pivotal regulator in Angiostrongylus cantonensis-induced eosinophilic meningoencephalitis
PLoS ONE·2019· 6 citedOpen Access
Matrix metalloproteinase-2 and matrix metalloproteinase-9 in mice with ocular toxocariasis
Parasitology Research·2019· 11 cited
Resveratrol relieves Angiostrongylus cantonensis – Induced meningoencephalitis by activating sirtuin-1
Acta Tropica·2017· 12 cited
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Frequent Co-authors

Kemin Chen(16), Ling-Yuh Shyu(8), Wu‐Chun Tu(7), Cheng‐You Lu(7), Hui-Lin Chou(6), H. H. Lee(6), K. M. Chen(6), Li‐Sung Hsu(4), Si‐Tse Jiang(4), K.P. Lan(4), K.M. Chen(4), H.H. Lee(4), Roger F. Hou(3), Ping-Sung Chiu(3), Hsiu-Hsiung Lee(3), Jeng‐Dong Hsu(3), Ping-Sung Chiu(2), Cheng‐Chen Chen(2), Yu‐Kai Tseng(2), Jer‐Yuh Liu(2)