Allyson J. Merrell

Arsenal Biosciences (United States) — United States

Medicine · Health Sciences

12h-index2.3kcitations31works3.92yr avg
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Research Topics

Pancreatic function and diabetes(6), Cancer Cells and Metastasis(5), Neonatal Respiratory Health Research(5), Liver physiology and pathology(5), Congenital Diaphragmatic Hernia Studies(5)

Publications31 total

DINOcell: learning generalizable perturbation effects through self-distillation
2025Open Access
1125 gx1: virtual target identification for overcoming T cell exhaustion
Regular and Young Investigator Award Abstracts·2025Open Access
334 Computational mapping of CAR-T cell exhaustion through single-cell perturbation screens
Regular and Young Investigator Award Abstracts·2024Open Access
282 Improving solid tumor CAR-T therapies by modulating T cell transcriptional states using combinatorial <i>in vitro</i> CRISPR screening followed by <i>in vivo</i> validation
Regular and Young Investigator Award Abstracts·2024Open Access
Abstract 7042: Enhancing TCR T cell function in solid tumors through <i>in vivo</i> combinatorial screens and single-cell analysis
Cancer Research·2024
Abstract 7034: Pooled CRISPR screening coupled with single-cell sequencing identifies modifiers of CAR T cell state in the context of chronic antigen stimulation
Cancer Research·2024
Cellular reprogramming in vivo initiated by SOX4 pioneer factor activity
Nature Communications·2024· 27 citedOpen Access
Evidence for in vitro extensive proliferation of adult hepatocytes and biliary epithelial cells
Stem Cell Reports·2023· 5 citedOpen Access
Physiological reprogramming <i>in vivo</i> mediated by Sox4 pioneer factor activity
2023· 2 citedOpen Access
Evidence for <i>in vitro</i> extensive proliferation of adult hepatocytes and biliary epithelial cells
2023Open Access
Fibroblast-derived Hgf controls recruitment and expansion of muscle during morphogenesis of the mammalian diaphragm
eLife·2022· 12 citedOpen Access
Author response: Fibroblast-derived Hgf controls recruitment and expansion of muscle during morphogenesis of the mammalian diaphragm
2022Open Access
Dissecting phenotypic transitions in metastatic disease via photoconversion-based isolation
eLife·2021· 5 citedOpen Access
Author response: Dissecting phenotypic transitions in metastatic disease via photoconversion-based isolation
2021Open Access
Dynamic Transcriptional and Epigenetic Changes Drive Cellular Plasticity in the Liver
Hepatology·2021· 43 citedOpen Access
Epigenetic and Transcriptional Control of the Epidermal Growth Factor Receptor Regulates the Tumor Immune Microenvironment in Pancreatic Cancer
Cancer Discovery·2020· 129 citedOpen Access
Dissecting phenotypic transitions in metastatic disease via photoconversion-based isolation
2020· 1 citedOpen Access
Global Regulation of the Histone Mark H3K36me2 Underlies Epithelial Plasticity and Metastatic Progression
Cancer Discovery·2020· 86 citedOpen Access
Abstract A59: CRISPR screen identifies global regulation of H3K36me2 as an epigenomic mechanism underlying epithelial plasticity in pancreatic ductal adenocarcinoma
Cancer Research·2019
Abstract B38: Calcium signaling induces a partial EMT in pancreatic ductal adenocarcinoma
Cancer Research·2019
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Frequent Co-authors

Ben Z. Stanger(17), Jinyang Li(14), Yogev Sela(8), Salina Yuan(8), Gabrielle Kardon(6), Catherine Oh(6), Brendan Galvin(6), W. Nicholas Haining(6), Taiji Yamazoe(5), Takeshi Katsuda(5), Josephine Susanto(5), Ashley Cass(5), David DeTomaso(5), Julie Chow(5), Andrew Cardozo(5), Marian Sandoval(5), Levi Gray-Rupp(5), Robert J. Norgard(4), Irfan A. Asangani(4), Grace Zheng(4)