José Luís Fachi

Universidade Estadual de Campinas (UNICAMP) — Brazil

Biochemistry, Genetics and Molecular Biology · Life Sciences

20h-index3.9kcitations53works10.62yr avg
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Research Topics

Gut microbiota and health(17), IL-33, ST2, and ILC Pathways(16), Immune Cell Function and Interaction(11), Clostridium difficile and Clostridium perfringens research(10), Eosinophilic Esophagitis(7)

Publications53 total

Differential usage of IL22 distal elements by innate and adaptive cells 3615
The Journal of Immunology·2025Open Access
HIF-1 attenuates high-fiber diet-mediated proliferation and stemness of colonic epithelium
Gut Microbes·2025· 2 citedOpen Access
Circadian circuits control plasticity of group 3 innate lymphoid cells by sustaining epigenetic configuration of RORγt
Nature Immunology·2025· 5 cited
Obesity‐Induced Metabolic Priming Exacerbates <scp>SARS</scp>‐<scp>CoV</scp>‐2 Inflammation
Immunology·2025Open Access
Cell type-specific enhancers regulate IL-22 expression in innate and adaptive lymphoid cells
2025· 1 citedOpen Access
Rorγt-positive dendritic cells are required for the induction of peripheral regulatory T cells in response to oral antigens
Cell·2025· 50 cited
Species- and strain-specific microbial modulation of interferon, innate immunity, and epithelial barrier in 2D air–liquid interface respiratory epithelial cultures
BMC Biology·2025· 3 citedOpen Access
Fiber- and acetate-mediated modulation of MHC-II expression on intestinal epithelium protects from Clostridioides difficile infection
Cell Host & Microbe·2025· 14 citedOpen Access
INDENIZAÇÃO POR DANO MORAL PRESUMIDO NOS INDEFERIMENTOS DE BENEFÍCIOS POR INCAPACIDADE PARA TRABALHADORES RURAIS (SEGURADOS ESPECIAIS)
2025Open Access
NKp46 <sup>+</sup> ILC3s promote early neutrophil defense against <i>Clostridioides difficile</i> infection through GM-CSF secretion
Proceedings of the National Academy of Sciences·2024· 9 citedOpen Access
Editorial: Molecular insights of microbiota and innate lymphoid cell interactions
Frontiers in Immunology·2024Open Access
TREM2 deficiency reprograms intestinal macrophages and microbiota to enhance anti–PD-1 tumor immunotherapy
Science Immunology·2024· 37 citedOpen Access
The IRE1α/XBP1 pathway sustains cytokine responses of group 3 innate lymphoid cells in inflammatory bowel disease
Journal of Clinical Investigation·2024· 23 citedOpen Access
Deficiency of IL-22–binding protein enhances the ability of the gut microbiota to protect against enteric pathogens
Proceedings of the National Academy of Sciences·2024· 9 citedOpen Access
Review of: "[Case Study] Targeting the Warburg Effect with the Glucose Mutation Theory: A Case Study of 36-Year-Old Female Treated for Stage IV Metastatic TPBCUsing Glucosodiene Over a 15-Day Period"
2024Open Access
Reviewing the Clostridioides difficile Mouse Model: Insights into Infection Mechanisms
Microorganisms·2024· 8 citedOpen Access
Hyperbaric oxygen augments susceptibility to <i>C. difficile</i> infection by impairing gut microbiota ability to stimulate the HIF-1α-IL-22 axis in ILC3
Gut Microbes·2024· 20 citedOpen Access
A distinct human cell type expressing MHCII and RORγt with dual characteristics of dendritic cells and type 3 innate lymphoid cells
Proceedings of the National Academy of Sciences·2023· 36 citedOpen Access
Species- and strain-effects in interferon, innate immunity, and barrier transcriptional response of microbiome interactions of 3D respiratory epithelial cultures
2023Open Access
Correction: Inulin diet uncovers complex diet-microbiota-immune cell interactions remodeling the gut epithelium
Microbiome·2023· 6 citedOpen Access
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Frequent Co-authors

Marco Colonna(26), Marco Aurélio Ramirez Vinolo(25), Laís Passariello Pral(13), Susan Gilfillan(11), Sarah de Oliveira(11), Renan Oliveira Corrêa(9), Blanda Di Luccia(8), Marina Cella(8), Alina Ulezko Antonova(7), Hosana Gomes Rodrigues(6), Niels Olsen Saraiva Câmara(6), Mariane Font Fernandes(6), Patrick Varga‐Weisz(5), Jaqueline de Souza Felipe(5), Cristiane Sécca(5), Tihana Tršan(5), Bishan Bhattarai(5), Fábio Takeo Sato(4), Angélica T. Vieira(4), Flaviano S. Martins(4)