Gökhan Güner

German Center for Neurodegenerative Diseases — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

8h-index483citations24works2.52yr avg
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Research Topics

ATP Synthase and ATPases Research(9), Alzheimer's disease research and treatments(5), RNA Research and Splicing(3), Cellular transport and secretion(3), Machine Learning in Bioinformatics(3)

Publications24 total

Charting γ-secretase substrates by explainable AI
Nature Communications·2025· 3 citedOpen Access
Cleavage efficiency of the intramembrane protease γ‐secretase is reduced by the palmitoylation of a substrate's transmembrane domain
The FASEB Journal·2024· 2 citedOpen Access
Cooperation of N- and C-terminal substrate transmembrane domain segments in intramembrane proteolysis by γ-secretase
Communications Biology·2023· 8 citedOpen Access
Proteolytically generated soluble Tweak Receptor Fn14 is a blood biomarker for γ‐secretase activity
EMBO Molecular Medicine·2022· 12 citedOpen Access
Differences in inflammatory markers in COVID-19 mortality in patients aged 18-65, 65-80 and 80 years and older
SANAMED·2022Open Access
The <i>Uppsala APP</i> deletion causes early onset autosomal dominant Alzheimer’s disease by altering APP processing and increasing amyloid β fibril formation
Science Translational Medicine·2021· 44 citedOpen Access
Roles of developmentally regulated KIF2A alternative isoforms in cortical neuron migration and differentiation
Development·2021· 14 citedOpen Access
Investigation of health insurance costs of the patients with mild Covid-19 symptoms in emergency room
SANAMED·2021Open Access
An optimized quantitative proteomics method establishes the cell type‐resolved mouse brain secretome
The EMBO Journal·2020· 86 citedOpen Access
The substrate repertoire of γ-secretase/presenilin
Seminars in Cell and Developmental Biology·2020· 187 citedOpen Access
Seizure protein 6 controls glycosylation and trafficking of kainate receptor subunits GluK2 and GluK3
The EMBO Journal·2020· 39 citedOpen Access
Quantitative secretome analysis establishes the cell type-resolved mouse brain secretome
2020· 1 citedOpen Access
Roles of developmentally regulated KIF2A alternative isoforms in cortical neuron migration and differentiation
2020· 1 cited
Pathology-linked protease caught in action
Science·2019· 1 cited
NEUROD2 Regulates<i>Stim1</i>Expression and Store-Operated Calcium Entry in Cortical Neurons
eNeuro·2017· 25 citedOpen Access
Genome-wide target analysis of NEUROD2 provides new insights into regulation of cortical projection neuron migration and differentiation
BMC Genomics·2015· 60 citedOpen Access
Additional file 7: of Genome-wide target analysis of NEUROD2 provides new insights into regulation of cortical projection neuron migration and differentiation
Figshare·2015Open Access
Additional file 6: of Genome-wide target analysis of NEUROD2 provides new insights into regulation of cortical projection neuron migration and differentiation
Figshare·2015Open Access
Additional file 8: of Genome-wide target analysis of NEUROD2 provides new insights into regulation of cortical projection neuron migration and differentiation
Figshare·2015Open Access
Additional file 2: of Genome-wide target analysis of NEUROD2 provides new insights into regulation of cortical projection neuron migration and differentiation
Figshare·2015Open Access
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Frequent Co-authors

Efil Bayam(12), Gulayse Ince-Dunn(12), Stefan F. Lichtenthaler(10), Gulcan Semra Sahin(10), Gizem Guzelsoy(10), Alkan Kabakçıoğlu(10), Stephan A. Müller(6), Dmitrij Frishman(4), Dieter Langosch(4), Harald Steiner(4), Johanna Tüshaus(3), Georg Jocher(3), Cansu Akkaya(3), Marlene Aßfalg(3), Evans Kataka(2), Jan Zaucha(2), Laura Sebastián Monasor(2), Minhui Su(2), Sabina Tahirović(2), Mikael Simons(2)