Sarah Spiegel

Virginia Commonwealth University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

123h-index53.1kcitations597works1.32yr avg
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Research Topics

Sphingolipid Metabolism and Signaling(438), Lipid Membrane Structure and Behavior(128), Cellular transport and secretion(83), Endoplasmic Reticulum Stress and Disease(78), Protein Kinase Regulation and GTPase Signaling(58)

Publications595 total

Supplementary Data from Sphingosine Kinase 2 in Stromal Fibroblasts Creates a Hospitable Tumor Microenvironment in Breast Cancer
2025Open Access
Supplementary Data from Sphingosine Kinase 2 in Stromal Fibroblasts Creates a Hospitable Tumor Microenvironment in Breast Cancer
2025Open Access
Supplementary Data from Sphingosine Kinase 2 in Stromal Fibroblasts Creates a Hospitable Tumor Microenvironment in Breast Cancer
2025Open Access
Supplementary Data from Sphingosine Kinase 2 in Stromal Fibroblasts Creates a Hospitable Tumor Microenvironment in Breast Cancer
2025Open Access
Supplementary Data from Sphingosine Kinase 2 in Stromal Fibroblasts Creates a Hospitable Tumor Microenvironment in Breast Cancer
2025Open Access
Supplementary Data from Sphingosine Kinase 2 in Stromal Fibroblasts Creates a Hospitable Tumor Microenvironment in Breast Cancer
2025Open Access
Depot-specific roles for sphingosine kinase 1 in conversion of white adipose to thermogenic adipose
2025Open Access
Abstract C080: Biosocial disparities drive glycoxidation to induce adipocyte differentiation in the prostate tumor microenvironment
Cancer Epidemiology Biomarkers & Prevention·2025
Abstract 7403: Colorectal neoplasia rates in Li Fraumeni syndrome
Cancer Research·2025
Activation of sphingosine-1-phosphate receptor subtype 1 in the central nervous system contributes to morphine-induced hyperalgesia and antinociceptive tolerance in rodents: erratum
Pain·2025
Ozanimod, a Functional Sphingosine-1-Phosphate Receptor 1 Antagonist, Attenuates Paclitaxel-Induced Cognitive Impairment (Abstract ID: 166985)
Journal of Pharmacology and Experimental Therapeutics·2025
Dissociation between the anti-allodynic effects of fingolimod (FTY720) and desensitization of S1P1 receptor-mediated G-protein activation in a mouse model of sciatic nerve injury
Neuropharmacology·2024· 2 citedOpen Access
FTY720/Fingolimod mitigates paclitaxel‐induced Sparcl1‐driven neuropathic pain and breast cancer progression
The FASEB Journal·2024· 11 citedOpen Access
Sphingosine kinase 2 and p62 regulation are determinants of sexual dimorphism in hepatocellular carcinoma
Molecular Metabolism·2024· 3 citedOpen Access
ORMDL mislocalization by impaired autophagy in Niemann-Pick type C disease leads to increased de novo sphingolipid biosynthesis
Journal of Lipid Research·2024· 4 citedOpen Access
Overexpression of ORMDL3 confers sexual dimorphism in diet-induced non-alcoholic steatohepatitis
Molecular Metabolism·2023· 4 citedOpen Access
Sphingosine kinase 1/S1P receptor signaling axis is essential for cellular uptake of Neisseria meningitidis in brain endothelial cells
PLoS Pathogens·2023· 8 citedOpen Access
The sterol transporter STARD3 transports sphingosine at ER-lysosome contact sites
2023· 15 citedOpen Access
Sphingosine-1-phosphate and its receptors in vascular endothelial and lymphatic barrier function
Journal of Biological Chemistry·2023· 53 citedOpen Access
Supplementary Table S3 from ABCC1-Exported Sphingosine-1-phosphate, Produced by Sphingosine Kinase 1, Shortens Survival of Mice and Patients with Breast Cancer
2023Open Access
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Frequent Co-authors

Sheldon Milstien(25), Michael Maceyka(13), Ana Olivera(9), Nitai C. Hait(7), Lisa C. Edsall(6), Jeremy C. Allegood(5), Kazuaki Takabe(5), Olivier Cuvillier(4), Kuzhuvelil B. Harikumar(4), Graham M. Strub(4), Tomasz Kordula(4), Steven W. Paugh(4), Takafumi Kohama(4), Shawn G. Payne(4), James R. Van Brocklyn(3), Timothy Hla(3), Sergio E. Alvarez(3), Eugene Y. Kim(3), Richard L. Proia(3), Alfred H. Merrill(3)