David E. Lanar

Walter Reed Army Institute of Research — United States

Medicine · Health Sciences

51h-index7.7kcitations119works0.02yr avg
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Research Topics

Malaria Research and Control(84), Mosquito-borne diseases and control(59), vaccines and immunoinformatics approaches(27), Complement system in diseases(25), Immunotherapy and Immune Responses(15)

Publications119 total

First-in-human assessment of safety and immunogenicity of low and high doses of Plasmodium falciparum malaria protein 013 (FMP013) administered intramuscularly with ALFQ adjuvant in healthy malaria-naïve adults
Vaccine·2022· 25 citedOpen Access
RTS,S/AS01E immunization increases antibody responses to vaccine-unrelated Plasmodium falciparum antigens associated with protection against clinical malaria in African children: a case-control study
BMC Medicine·2019· 43 citedOpen Access
Differential Patterns of IgG Subclass Responses to Plasmodium falciparum Antigens in Relation to Malaria Protection and RTS,S Vaccination
Frontiers in Immunology·2019· 85 citedOpen Access
Identification of Immune Signatures of Novel Adjuvant Formulations Using Machine Learning
Scientific Reports·2018· 38 citedOpen Access
Author Correction: A comprehensive model for assessment of liver stage therapies targeting Plasmodium vivax and Plasmodium falciparum
Nature Communications·2018· 7 citedOpen Access
Optimization of incubation conditions of Plasmodium falciparum antibody multiplex assays to measure IgG, IgG1–4, IgM and IgE using standard and customized reference pools for sero-epidemiological and vaccine studies
Malaria Journal·2018· 22 citedOpen Access
A comprehensive model for assessment of liver stage therapies targeting Plasmodium vivax and Plasmodium falciparum
Nature Communications·2018· 191 citedOpen Access
Immune response to antigen adsorbed to aluminum hydroxide particles: Effects of co-adsorption of ALF or ALFQ adjuvant to the aluminum-antigen complex
Journal of Controlled Release·2018· 52 citedOpen Access
Self-assembling protein nanoparticles with built-in flagellin domains increases protective efficacy of a Plasmodium falciparum based vaccine
Vaccine·2017· 65 citedOpen Access
Sero-catalytic and Antibody Acquisition Models to Estimate Differing Malaria Transmission Intensities in Western Kenya
Scientific Reports·2017· 23 citedOpen Access
The use of a P. falciparum specific coiled-coil domain to construct a self-assembling protein nanoparticle vaccine to prevent malaria
Journal of Nanobiotechnology·2017· 38 citedOpen Access
Protein nanovaccine confers robust immunity against Toxoplasma
npj Vaccines·2017· 58 citedOpen Access
Strain-specific Plasmodium falciparum growth inhibition among Malian children immunized with a blood-stage malaria vaccine
PLoS ONE·2017· 15 citedOpen Access
Development of a self-assembling protein nanoparticle vaccine targeting Plasmodium falciparum Circumsporozoite Protein delivered in three Army Liposome Formulation adjuvants
Vaccine·2017· 61 citedOpen Access
Malaria Vaccines in Clinical Development: Introduction and Recombinant/Subunit Approaches
2016
Strain-specific Plasmodium falciparum multifunctional CD4+ T cell cytokine expression in Malian children immunized with the FMP2.1/AS02A vaccine candidate
Vaccine·2016· 11 cited
Contrasting Patterns of Serologic and Functional Antibody Dynamics to Plasmodium falciparum Antigens in a Kenyan Birth Cohort
Clinical and Vaccine Immunology·2015· 26 citedOpen Access
Malaria vaccine based on self-assembling protein nanoparticles
Expert Review of Vaccines·2015· 38 cited
Optimizing the design of protein nanoparticles as carriers for vaccine applications
Nanomedicine Nanotechnology Biology and Medicine·2015· 30 citedOpen Access
The hierarchy of two different immunodominant epitopes influences CD4+ T cell responses (APP5P.112)
The Journal of Immunology·2015
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Frequent Co-authors

Sheetij Dutta(16), D. Gray Heppner(11), Urszula Krzych(8), Lisa A. Ware(8), Carter L. Diggs(7), Kent E. Kester(7), Peter Burkhard(7), Arnoldo Barbosa(7), Marie‐Claude Dubois(6), Lorraine Soisson(6), Stephen A. Kaba(6), David J. Conway(5), W. Ripley Ballou(5), V. Ann Stewart(5), Joe Cohen(5), J. David Haynes(5), Christian F. Ockenhouse(4), Evelina Angov(4), Kevin C. Kain(4), Chandy C. John(4)