William Bosron

Indiana University School of Medicine

Medicine · Health Sciences

55h-index9.2kcitations125works0.02yr avg
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Research Topics

Alcohol Consumption and Health Effects(60), Liver Disease Diagnosis and Treatment(17), Pharmacogenetics and Drug Metabolism(17), Pancreatic function and diabetes(17), Muscle metabolism and nutrition(15)

Publications125 total

Alcohol Dehydrogenases
Elsevier eBooks·2018
Alcohol Dehydrogenases
Elsevier eBooks·2010· 25 cited
Zebrafish fetal alcohol syndrome model: effects of ethanol are rescued by retinoic acid supplement
Alcohol·2009· 134 citedOpen Access
Human Carboxylesterases: An Update on CES1, CES2 and CES3
Protein and Peptide Letters·2009· 133 cited
Expression of carboxylesterase and lipase genes in rat liver cell-types
Biochemical and Biophysical Research Communications·2008· 51 citedOpen Access
Expression and Characterization of a Human Carboxylesterase 2 Splice Variant
Journal of Pharmacology and Experimental Therapeutics·2007· 24 cited
A multiple reaction monitoring method for absolute quantification of the human liver alcohol dehydrogenase ADH1C1 isoenzyme
Analytical Biochemistry·2007· 98 cited
Characterization and activation of vitamin A-sorted rat hepatic stellate cells
Digestive and Liver Disease·2006
Hydrolysis of Capecitabine to 5′-Deoxy-5-fluorocytidine by Human Carboxylesterases and Inhibition by Loperamide
Journal of Pharmacology and Experimental Therapeutics·2005· 180 cited
Methylphenidate Is Stereoselectively Hydrolyzed by Human Carboxylesterase CES1A1
Journal of Pharmacology and Experimental Therapeutics·2004· 186 cited
HYDROLYSIS OF IRINOTECAN AND ITS OXIDATIVE METABOLITES, 7-ETHYL-10-[4-N-(5-AMINOPENTANOIC ACID)-1-PIPERIDINO] CARBONYLOXYCAMPTOTHECIN AND 7-ETHYL-10-[4-(1-PIPERIDINO)-1-AMINO]-CARBONYLOXYCAMPTOTHECIN, BY HUMAN CARBOXYLESTERASES CES1A1, CES2, AND A NEWLY EXPRESSED CARBOXYLESTERASE ISOENZYME, CES3
Drug Metabolism and Disposition·2004· 134 cited
Inhibition of carboxyleseterase activity: Can co-administered agents reduce irinotecan and capecitabine activation?
Cancer Research·2004
Carboxylesterases expressed in human colon tumor tissue and their role in CPT-11 hydrolysis.
PubMed·2003· 123 cited
Structure–function relationships in human Class III alcohol dehydrogenase (formaldehyde dehydrogenase)
Chemico-Biological Interactions·2003· 25 cited
STRUCTURE-FUNCTION RELATIONSHIPS IN HUMAN CLASS III ALCOHOL DEHYDROGENASE (FORMALDEHYDE DEHYROGENASE)
Journal of Electron Spectroscopy and Related Phenomena·2003
1296 Hormone sensitive lipase is a retinyl ester hydrolase in hepatic stellate cells
Hepatology·2003
Human Glutathione-Dependent Formaldehyde Dehydrogenase. Structural Changes Associated with Ternary Complex Formation
Biochemistry·2002· 67 cited
Binary Complex of Human Glutathione-Dependent Formaldehyde Dehydrogenase with NAD(H)
2002
Identification of microsomal rat liver carboxylesterases and their activity with retinyl palmitate
European Journal of Biochemistry·2002· 50 citedOpen Access
Human Glutathione-Dependent Formaldehyde Dehydrogenase. Structures of Apo, Binary, and Inhibitory Ternary Complexes
Biochemistry·2002· 82 cited
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Frequent Co-authors

Thomas D. Hurley(13), Ting‐Kai Li(8), Howard J. Edenberg(6), Carol L. Stone(6), Tsai‐Kun Li(5), Sonal P. Sanghani(5), Paresh C. Sanghani(5), David W. Crabb(4), Monica R. Brzezinski(4), Robert A. Dean(4), Daryl J. Murry(4), Wilhelmina I. Davis(4), Bert L. Vallée(4), Evgenia V. Pindel(3), Natalia Y. Kedishvili(3), Sara K. Quinney(3), Leslie J. Magnes(3), Ting Kai Li(3), Lucinda G. Carr(2), Trent L. Abraham(2)