Lingfeng Tong

Shanghai Jiao Tong University — China

Biochemistry, Genetics and Molecular Biology · Life Sciences

11h-index839citations25works15.32yr avg
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Research Topics

Cancer, Hypoxia, and Metabolism(7), Diet and metabolism studies(7), Biochemical Acid Research Studies(7), Adipose Tissue and Metabolism(6), Metabolism and Genetic Disorders(4)

Publications25 total

Metabolic Reprogramming: A Crucial Contributor to Anticancer Drug Resistance
MedComm·2025· 2 citedOpen Access
Targeting MondoA–TXNIP restores antitumour immunity in lactic-acid-induced immunosuppressive microenvironment
Nature Metabolism·2025· 9 cited
Transketolase promotes MAFLD by limiting inosine-induced mitochondrial activity
Cell Metabolism·2024· 35 cited
Supplementary Data from Transketolase Deficiency Protects the Liver from DNA Damage by Increasing Levels of Ribose 5-Phosphate and Nucleotides
2023Open Access
Data from Transketolase Deficiency Protects the Liver from DNA Damage by Increasing Levels of Ribose 5-Phosphate and Nucleotides
2023Open Access
Data from Transketolase Deficiency Protects the Liver from DNA Damage by Increasing Levels of Ribose 5-Phosphate and Nucleotides
2023Open Access
Supplementary Data from Transketolase Deficiency Protects the Liver from DNA Damage by Increasing Levels of Ribose 5-Phosphate and Nucleotides
2023Open Access
Loss of transketolase promotes the anti-diabetic role of brown adipose tissues
Journal of Endocrinology·2022· 5 cited
<scp>MEK1</scp>‐dependent <scp>MondoA</scp> phosphorylation regulates glucose uptake in response to ketone bodies in colorectal cancer cells
Cancer Science·2022· 4 citedOpen Access
Non-oxidative pentose phosphate pathway controls regulatory T cell function by integrating metabolism and epigenetics
Nature Metabolism·2022· 92 cited
The Synthesis of 5-Hydroxybenzofurans via Tandem In Situ Oxidative Coupling and Cyclization
SynOpen·2022· 3 citedOpen Access
Nuclear Tkt promotes ischemic heart failure via the cleaved Parp1/Aif axis
Basic Research in Cardiology·2022· 23 cited
Loss of SIRT5 promotes bile acid-induced immunosuppressive microenvironment and hepatocarcinogenesis
Journal of Hepatology·2022· 170 cited
TKT maintains intestinal ATP production and inhibits apoptosis-induced colitis
Cell Death and Disease·2021· 37 citedOpen Access
MondoA–Thioredoxin-Interacting Protein Axis Maintains Regulatory T-Cell Identity and Function in Colorectal Cancer Microenvironment
Gastroenterology·2021· 95 cited
ERα down‐regulates carbohydrate responsive element binding protein and decreases aerobic glycolysis in liver cancer cells
Journal of Cellular and Molecular Medicine·2021· 5 citedOpen Access
Dysregulated Glutamate Transporter SLC1A1 Propels Cystine Uptake via Xc− for Glutathione Synthesis in Lung Cancer
Cancer Research·2020· 95 citedOpen Access
HNF4α regulates sulfur amino acid metabolism and confers sensitivity to methionine restriction in liver cancer
Nature Communications·2020· 122 citedOpen Access
Transketolase deficiency in adipose tissues protects mice from diet-induced obesity by promoting lipolysis
2020Open Access
Transketolase deficiency in adipose tissues protects mice from diet-induced obesity by promoting lipolysis
2020Open Access
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Frequent Co-authors

Xuemei Tong(22), Yakui Li(19), Yemin Zhu(19), Ying Lu(15), Tian‐Le Xu(14), Minle Li(11), Lifang Wu(10), Qi Liu(8), Ping Zhang(8), Jian Meng(8), Feng Ming(8), Lifang Wu(8), Shuhai Lin(6), Hanbei Chen(6), Xiaochuan Gu(6), Ping Zhang(6), Liang Zheng(6), Nannan Xu(5), Ming Feng(5), Na Tian(5)