Leena Penttilä

University of Eastern Finland — Finland

Biochemistry, Genetics and Molecular Biology · Life Sciences

16h-index914citations27works0.02yr avg
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Research Topics

Glycosylation and Glycoproteins Research(24), Carbohydrate Chemistry and Synthesis(15), Cell Adhesion Molecules Research(7), Galectins and Cancer Biology(7), Proteoglycans and glycosaminoglycans research(4)

Publications27 total

Effects of triaryl phosphates on mouse and human nuclear receptors
Biochemical Pharmacology·2003· 69 cited
Glycosulfopeptides with O-Glycans Containing Sialylated and Polyfucosylated Polylactosamine Bind with Low Affinity to P-selectin
Journal of Biological Chemistry·2002· 59 citedOpen Access
BIOSYNTHESIS OF GDP-6-DEOXY-D-TALOSE IN ACTINOBACILLUS ACTINOMYCETEMCOMITANS
XXIst International Carbohydrate Symposium 2002·2002
Several polylactosamine-modifying glycosyltransferases also use internal GalNAc 1-4GlcNAc units of synthetic saccharides as acceptors
Glycobiology·2002· 10 citedOpen Access
Analysis of nucleotide sugars from cell lysates by ion-pair solid-phase extraction and reversed-phase high-performance liquid chromatography
Glycoconjugate Journal·2001· 110 cited
Enzymatic synthesis of α3′sialylated and multiply α3fucosylated biantennary polylactosamines
European Journal of Biochemistry·1999· 21 cited
Improved enzymatic synthesis of a highly potent oligosaccharide antagonist of L‐selectin
FEBS Letters·1997· 17 citedOpen Access
The β1,6‐GlcNAc transferase activity present in hog gastric mucosal microsomes catalyses site‐specific branch formation on a long polylactosamine backbone
FEBS Letters·1997· 16 citedOpen Access
L‐selectin ligands in rat high endothelium: multivalent sialyl Lewis x glycans are high‐affinity inhibitors of lymphocyte adhesion
European Journal of Immunology·1997· 23 cited
Synthesis of a new nanomolar saccharide inhibitor of lymphocyte adhesion: different polylactosamine backbones present multiple sialyl Lewis x determinants to L-selectin in high-affinity mode
Glycobiology·1997· 54 citedOpen Access
Synthesis of a tetravalent sialyl Lewis x glycan, a high-affinity inhibitor of L-selectin-mediated lymphocyte binding to endothelium
Glycobiology·1996· 48 citedOpen Access
Synthesis of a Divalent Sialyl Lewis x O‐glycan, a Potent Inhibitor of Lymphocyte‐Endothelium Adhesion
European Journal of Biochemistry·1995· 67 citedOpen Access
De novo expression of endothelial sialyl Lewis(a) and sialyl Lewis(x) during cardiac transplant rejection: superior capacity of a tetravalent sialyl Lewis(x) oligosaccharide in inhibiting L-selectin-dependent lymphocyte adhesion.
The Journal of Experimental Medicine·1995· 101 citedOpen Access
Enzymic Synthesis of Octadecameric Saccharides of Multiply Branched Blood Group I-Type, Carrying Four Distal .alpha.1,3-Galactose or .beta.1,3-GlcNAc Residues. [Erratum to document cited in CA122:291382]
Biochemistry·1995· 1 cited
Enzyme‐assisted synthesis of a bivalent high‐affinity dodecasaccharide inhibitor of mouse gamete adhesion The length of the chains carrying distal α1,3‐bonded galactose residues is critical
FEBS Letters·1995· 14 citedOpen Access
Enzymic Synthesis of Octadecameric Saccharides of Multiply Branched Blood Group I-Type, Carrying Four Distal .alpha.1,3-Galactose or .beta.1,3-GlcNAc Residues
Biochemistry·1995· 27 cited
Oligosaccharide Constructs with Defined Structures That Inhibit Binding of Mouse Sperm to Unfertilized Eggs in Vitro
Biochemistry·1995· 144 cited
Enzyme‐aided construction of medium‐sized alditols of complete O‐linked saccharides
FEBS Letters·1994· 11 cited
A novel β‐<i>N</i>‐acetylglucosaminidase activity in hog gastric mucosal microsomes: Preferential hydrolysis of terminal GlcNAcß1‐3 linkages in GlcNAcß1‐3(GlcNAcß1‐6)Galß1‐GlcNAc, but GlcNAcß1‐6 linkages in GlcNAcß1‐3(GlcNAcß1‐6)Gal
FEBS Letters·1993· 6 cited
S1.19 Linear oligo-N-acetyllactosaminoglycans with two or three internally located galactoses are efficiently branched by human serum�1,6-GlcNAc transferase
Glycoconjugate Journal·1993
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Frequent Co-authors

Ossi Renkonen(20), Antti Seppo(13), Hannu Maaheimo(12), Ritva Niemelä(11), Anne Leppänen(11), Jari Helin(11), Risto Renkonen(8), Juha Pekka Turunen(5), O. Renkonen(4), Catherine E. Costello(4), Jarkko Räbinä(3), Sanna Toppila‐Salmi(3), Heidi Salminen(3), Anita Keane(3), Anne Makkonen(3), Nina Järvinen(2), Timo Paavonen(2), Jari Helin(2), Hannu Maaheimo(2), Sari Lusa(2)