Mark Duxon

Neuroscience · Life Sciences

20h-index1.7kcitations27works0.02yr avg
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Research Topics

Neurotransmitter Receptor Influence on Behavior(15), Neuroscience and Neuropharmacology Research(8), Stress Responses and Cortisol(6), Neuroendocrine regulation and behavior(6), Memory and Neural Mechanisms(4)

Publications27 total

Ketamine supresses REM sleep and markedly increases EEG gamma oscillations in the Wistar Kyoto rat model of treatment-resistant depression
Behavioural Brain Research·2023· 6 citedOpen Access
The development of an Irwin-like test in the nonhuman primate for CNS safety assessment
Journal of Pharmacological and Toxicological Methods·2012· 3 cited
How Good Are Current Approaches to Nonclinical Evaluation of Abuse and Dependence?
Journal of Pharmacology and Experimental Therapeutics·2010· 33 cited
Current approaches and issues in non-clinical evaluation of abuse and dependence
Journal of Pharmacological and Toxicological Methods·2010· 27 cited
SB-649915-B, a Novel 5-HT1A/B Autoreceptor Antagonist and Serotonin Reuptake Inhibitor, is Anxiolytic and Displays Fast Onset Activity in the Rat High Light Social Interaction Test
Neuropsychopharmacology·2007· 50 citedOpen Access
Social threat and novel cage stress-induced sustained extracellular-regulated kinase1/2 (ERK1/2) phosphorylation but differential modulation of brain-derived neurotrophic factor (BDNF) expression in the hippocampus of NMRI mice
Neuroscience·2005· 59 cited
3,4-Dihydro-2H-benzoxazinones are 5-HT1A receptor antagonists with potent 5-HT reuptake inhibitory activity
Bioorganic & Medicinal Chemistry Letters·2004· 55 citedOpen Access
A novel behavioural registration system LABORAS™ and the social interaction paradigm detect long-term functional deficits following middle cerebral artery occlusion in the rat
Brain Research·2004· 15 cited
P52 REPEATED PSYCHOLOGICAL STRESS AND PSYCHOSOCIAL THREAT DIFFERENTIALLY MODULATE THE ACTIVITY OF THE EXTRACELLULAR SIGNAL-REGULATED KINASE 1/2 PATHWAY IN THE HIPPOCAMPUS AND THE EXPRESSION OF ITS DOWNSTREAM TARGET BDNF
Behavioural Pharmacology·2004
Repeated sensory contact with aggressive mice rapidly leads to an anticipatory increase in core body temperature and physical activity that precedes the onset of aversive responding
European Journal of Neuroscience·2004· 53 cited
Localisation of NMU1R and NMU2R in human and rat central nervous system and effects of neuromedin-U following central administration in rats
Psychopharmacology·2004· 71 cited
Urotensin-II, a neuropeptide ligand for GPR14, induces c-fos in the rat brain
European Journal of Pharmacology·2004· 7 cited
Effects of fluoxetine on social behaviour and plasma corticosteroid levels in female mongolian gerbils
Behavioural Pharmacology·2003· 13 cited
LABORAS™: Initial pharmacological validation of a system allowing continuous monitoring of laboratory rodent behaviour
Journal of Neuroscience Methods·2003· 85 cited
Evidence implicating a role for orexin-1 receptor modulation of paradoxical sleep in the rat
Neuroscience Letters·2003· 85 cited
Further evidence for the predictive validity of the unstable elevated exposed plus-maze, a behavioural model of extreme anxiety in rats: Differential effects of fluoxetine and chlordiazepoxide
Behavioural Pharmacology·2002· 20 cited
5-HT 2C receptor mediation of unconditioned escape behaviour in the unstable elevated exposed plus maze
Psychopharmacology·2002· 27 cited
Ethopharmacological analysis of the unstable elevated exposed plus maze, a novel model of extreme anxiety: predictive validity and sensitivity to anxiogenic agents
Psychopharmacology·2002· 31 cited
Pharmacological profile of SB-357134: A potent, selective, brain penetrant, and orally active 5-HT6 receptor antagonist
Pharmacology Biochemistry and Behavior·2002· 64 cited
Effect of SB-243213, a selective 5-HT2C receptor antagonist, on the rat sleep profile
Pharmacology Biochemistry and Behavior·2002· 38 cited
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Frequent Co-authors

Neil Upton(6), C.A. Marsden(4), Kathryn R. Starr(4), Graham J. Riley(4), Jim J. Hagan(4), K.C.F. Fone(3), Declan N.C. Jones(3), Tania O. Stean(3), N. Upton(3), Gary Price(3), Marie‐Christine Pardon(3), Sheila King(3), Thomas P. Blackburn(2), Leann P. Quinn(2), Andrew Billinton(2), M.I Smith(2), D.C Piper(2), Jane Gartlon(2), Tracey Ashmeade(2), David R. Thomas(2)