Leah N. Klapper

Israel Institute for Biological Research — Israel

Medicine · Health Sciences

13h-index2.6kcitations20works4.02yr avg
OpenAlex↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Monoclonal and Polyclonal Antibodies Research(10), HER2/EGFR in Cancer Research(9), Glycosylation and Glycoproteins Research(6), Immunotherapy and Immune Responses(3), Chemokine receptors and signaling(3)

Publications20 total

Engineered human B cells targeting tumor-associated antigens exhibit antigen presentation and antibody-mediated functions
Frontiers in Immunology·2025· 7 citedOpen Access
Mouse B cells engineered to express an anti-HPV antibody elicit anti-tumor T cell responses.
PubMed·2025· 1 citedOpen Access
BL-8040, a CXCR4 antagonist, synergizes with the FLT3 inhibitor AC220 inducing apoptosis and reducing minimal residual disease to prolong survival of AML diseased mice
Clinical Lymphoma Myeloma & Leukemia·2015
The CXCR4 Antagonist BL-8040 Efficiently Induces Apoptosis and Inhibits The Survival Of AML Cells
Blood·2013· 5 cited
A Pegylated Leptin Antagonist Ameliorates CKD-Associated Cachexia in Mice
Journal of the American Society of Nephrology·2013· 38 citedOpen Access
177 Suppression of Gluten-Induced Enteropathy by the Copolymer Bl-7010 in NOD/DQ8 Transgenic Mice, an Animal Model of Celiac Disease (CD)
Gastroenterology·2013
Pharmacokinetic and efficacy study of cisplatin and paclitaxel formulated in a new injectable poly(sebacic-co-ricinoleic acid) polymer
European Journal of Pharmaceutics and Biopharmaceutics·2012· 19 cited
A Novel Recombinant Fusion Protein Encoding a 20-Amino Acid Residue of the Third Extracellular (E3) Domain of CCR2 Neutralizes the Biological Activity of CCL2
The Journal of Immunology·2009· 26 citedOpen Access
BL-1020: A novel antipsychotic drug with GABAergic activity and low catalepsy, is efficacious in a rat model of schizophrenia
European Neuropsychopharmacology·2008· 32 cited
The adjuvant activity of BAT antibody enables DNA vaccination to inhibit the progression of established autochthonous Her-2/neu carcinomas in BALB/c mice
Vaccine·2005· 18 cited
Specific inhibition of the reaction between a tumor-inhibitory antibody and the ErbB-2 receptor by a mimotope derived from a phage display library
Immunology Letters·2000· 13 cited
c-Cbl Is a Suppressor of the Neu Oncogene
Journal of Biological Chemistry·2000· 73 citedOpen Access
Tumor-inhibitory antibodies to HER-2/ErbB-2 may act by recruiting c-Cbl and enhancing ubiquitination of HER-2.
PubMed·2000· 351 cited
Inhibition of tumor growth by poly(ethylene glycol) derivatives of anti-ErbB2 antibodies
Cancer Immunology Immunotherapy·2000· 27 citedOpen Access
The ErbB-2/HER2 oncoprotein of human carcinomas may function solely as a shared coreceptor for multiple stroma-derived growth factors
Proceedings of the National Academy of Sciences·1999· 443 citedOpen Access
Biochemical and Clinical Implications of the ErbB/HER Signaling Network of Growth Factor Receptors
Advances in cancer research·1999· 546 cited
The oncogenic ErbB-2/ErbB-3 heterodimer is a surrogate receptor of the epidermal growth factor and betacellulin
Oncogene·1998· 99 cited
A subclass of tumor-inhibitory monoclonal antibodies to ErbB-2/HER2 blocks crosstalk with growth factor receptors
Oncogene·1997· 174 cited
Thrombin stimulates atrial natriuretic peptide secretion from rat cardiac atrium.
Journal of Pharmacology and Experimental Therapeutics·1996· 5 cited
Diversification of Neu differentiation factor and epidermal growth factor signaling by combinatorial receptor interactions.
The EMBO Journal·1996· 769 citedOpen Access

Frequent Co-authors

Yosef Yarden(9), Michael Sela(8), Ronit Pinkas‐Kramarski(3), Nora Vaisman(3), Gil Levkowitz(2), Sara Lavi(2), Esther Hurwitz(2), Rinat Tabakman(2), Ilan Winkler(2), Esmira Naftali(2), Natalie Zelikson(2), Yaron Vagima(2), Shmuel Hess(2), Débora Rosa Bublik(2), Adi Barzel(2), Alessio D. Nahmad(2), Sigal Tavor(2), Katia Beider(2), Hanna Wald(2), Orly Eizenberg(2)