Manuel Iglesias-Bexiga

Universidad de Granada — Spain

Biochemistry, Genetics and Molecular Biology · Life Sciences

11h-index320citations15works3.02yr avg
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Research Topics

Ubiquitin and proteasome pathways(5), Protein Structure and Dynamics(4), Computational Drug Discovery Methods(2), RNA and protein synthesis mechanisms(2), Glycosylation and Glycoproteins Research(2)

Publications15 total

Phage display identification of high-affinity ligands for human TSG101-UEV: A structural and thermodynamic study of PTAP recognition
International Journal of Biological Macromolecules·2024· 3 citedOpen Access
Interrogation of Essentiality in the Reconstructed Haemophilus influenzae Metabolic Network Identifies Lipid Metabolism Antimicrobial Targets: Preclinical Evaluation of a FabH β-Ketoacyl-ACP Synthase Inhibitor
mSystems·2022· 13 citedOpen Access
Phage display identification of nanomolar ligands for human NEDD4-WW3: Energetic and dynamic implications for the development of broad-spectrum antivirals
International Journal of Biological Macromolecules·2022· 8 citedOpen Access
Binding site plasticity in viral PPxY Late domain recognition by the third WW domain of human NEDD4
Scientific Reports·2019· 19 citedOpen Access
Ultrafast folding kinetics of WW domains reveal how the amino acid sequence determines the speed limit to protein folding
Proceedings of the National Academy of Sciences·2019· 14 citedOpen Access
Protein Folding Cooperativity and Thermodynamic Barriers of the Simplest β-Sheet Fold: A Survey of WW Domains
The Journal of Physical Chemistry B·2018· 13 cited
Csl2, a novel chimeric bacteriophage lysin to fight infections caused by Streptococcus suis, an emerging zoonotic pathogen
Scientific Reports·2017· 37 citedOpen Access
Deciphering how Cpl-7 cell wall-binding repeats recognize the bacterial peptidoglycan
Scientific Reports·2017· 31 citedOpen Access
PL3 Amidase, a Tailor-made Lysin Constructed by Domain Shuffling with Potent Killing Activity against Pneumococci and Related Species
Frontiers in Microbiology·2016· 38 citedOpen Access
Substrate recognition and catalysis by LytB, a pneumococcal peptidoglycan hydrolase involved in virulence
Scientific Reports·2015· 37 citedOpen Access
WW Domains of the Yes-Kinase-Associated-Protein (YAP) Transcriptional Regulator Behave as Independent Units with Different Binding Preferences for PPxY Motif-Containing Ligands
PLoS ONE·2015· 54 citedOpen Access
Insights into the peptidoglycan hydrolysis by the pneumococcal LytA autolysin
2013
Isothermal Titration Calorimetry: Thermodynamic Analysis of the Binding Thermograms of Molecular Recognition Events by Using Equilibrium Models
InTech eBooks·2013· 32 citedOpen Access
Human NEDD4 3RD WW Domain Complex with The Human T-cell Leukemia virus 1 GAG-Pro poliprotein Derived Peptide SDPQIPPPYVEP
2009
Thermodynamic Characterization of the Folding Equilibrium of the Human Nedd4-WW4 Domain: At the Frontiers of Cooperative Folding
Biochemistry·2009· 21 cited

Frequent Co-authors

Irene Luque(8), Margarita Menéndez(6), Pedro Garcı́a(5), José C. Martínez(5), Eva S. Cobos(4), Javier Ruiz‐Sanz(4), Noemí Bustamante(3), Javier Murciano‐Calles(3), Carles Corbi‐Verge(3), Francisco Castillo(2), Blas Blázquez(2), Palma Rico-Lastres(2), Roberto Díez‐Martínez(2), Shahriar Mobashery(2), Andrés Palencia(2), María J. Macias(2), Malwina Szczepaniak(2), Celia Sánchez de Medina(2), Víctor Muñoz(2), Tsutomu Oka(1)