Wim Pierson

Johnson & Johnson (United States) — United States

Immunology and Microbiology · Life Sciences

10h-index2.0kcitations28works4.82yr avg
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Research Topics

Immune Cell Function and Interaction(18), T-cell and B-cell Immunology(14), Immunotherapy and Immune Responses(12), Hepatitis B Virus Studies(8), Hepatitis C virus research(2)

Publications28 total

AAV-HBV mouse model replicates the intrahepatic immune landscape of chronic HBV patients at single-cell level
Frontiers in Immunology·2025· 3 citedOpen Access
Robust isolation protocol for mouse leukocytes from blood and liver resident cells for immunology research
PLoS ONE·2024Open Access
mRNA Therapeutic Vaccine for Hepatitis B Demonstrates Immunogenicity and Efficacy in the AAV-HBV Mouse Model
Vaccines·2024· 12 citedOpen Access
Retreatment with HBV siRNA Results in Additional Reduction in HBV Antigenemia and Immune Stimulation in the AAV-HBV Mouse Model
Viruses·2024· 4 citedOpen Access
Sustained Liver HBsAg Loss and Clonal T- and B-Cell Expansion upon Therapeutic DNA Vaccination Require Low HBsAg Levels
Vaccines·2023· 5 citedOpen Access
Sustained liver HBsAg loss and clonal T and B cell expansion upon therapeutic DNA vaccination require low HBsAg levels
Zenodo (CERN European Organization for Nuclear Research)·2023Open Access
Sustained liver HBsAg loss and clonal T and B cell expansion upon therapeutic DNA vaccination require low HBsAg levels
2023Open Access
Sustained liver HBsAg loss and clonal T and B cell expansion upon therapeutic DNA vaccination require low HBsAg levels
2023· 1 citedOpen Access
AAV-HBV mouse model replicates immune exhaustion patterns of chronic HBV patients at single-cell level
2023· 1 citedOpen Access
A single, oral dose of the TLR7 agonist JNJ-64794964 induces transcriptomic and phenotypic changes in peripheral immune cells in healthy adults
Antiviral Therapy·2023· 1 citedOpen Access
The metabolic hormone leptin promotes the function of TFH cells and supports vaccine responses
Nature Communications·2021· 40 citedOpen Access
Follicular Regulatory T Cells Can Access the Germinal Center Independently of CXCR5
Cell Reports·2020· 51 citedOpen Access
The adjuvant GLA-SE promotes human Tfh cell expansion and emergence of public TCRβ clonotypes
The Journal of Experimental Medicine·2019· 89 citedOpen Access
Follicular regulatory T cells can access the germinal centre independently of CXCR5
2019Open Access
Follicular Regulatory T Cells Can Access the Germinal Centre Independently of CXCR5
SSRN Electronic Journal·2019Open Access
Human blood T <sub>fr</sub> cells are indicators of ongoing humoral activity not fully licensed with suppressive function
Science Immunology·2017· 138 citedOpen Access
Genetische en cellulaire karakterisatie van Foxp3+ regulatoire T-cellen in ziekte en gezondheid
2014
A novel Zap70 mutation with reduced protein stability demonstrates the rate‐limiting threshold for Zap70 in T‐cell receptor signalling
Immunology·2013· 12 citedOpen Access
Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3+ regulatory T cells
Nature Immunology·2013· 232 citedOpen Access
A novel ZAP-70 mutation favors tolerogenic over immunogenic TCR signaling
2012
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Frequent Co-authors

Michelle A. Linterman(11), Adrian Liston(10), Isabel Nájera(9), Ellen Van Gulck(9), Koen Dockx(8), Nádia Conceição‐Neto(8), Liese Aerts(7), Dorien De Pooter(6), Ben De Clerck(6), Matthias Beyens(6), Vinod Krishna(6), Lore Verschueren(5), Marjolein Crabbe(5), Axel Kallies(4), Shimpei Kawamoto(4), Sidonia Fagarasan(4), Carola G. Vinuesa(4), Maurizio Vacca(4), Birgit Voeten(4), Mathias Vandenberk(4)