Takehiko Tosha

University of Hyogo — Japan

Chemistry · Physical Sciences

37h-index3.6kcitations219works4.82yr avg
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Research Topics

Metal-Catalyzed Oxygenation Mechanisms(49), Photosynthetic Processes and Mechanisms(46), Hemoglobin structure and function(26), Porphyrin Metabolism and Disorders(24), X-ray Diffraction in Crystallography(21)

Publications219 total

Real-time capture of domain movements during copper amine oxidase catalysis by mix-and-inject serial crystallography
Nature Communications·2025Open Access
Hydration‐coupled allosteric locking of a phenol‐ and zinc‐free bioactive insulin analog
FEBS Journal·2025
Ultrafast, remote-controlled protonation reaction enables structural changes in a phytochrome
Science Advances·2025· 1 citedOpen Access
Tracking Protein Motions using Serial Femtosecond Crystallography with X‐Ray Free‐Electron Laser
Current Protocols·2025Open Access
Time-resolved serial synchrotron and serial femtosecond crystallography of heme proteins using photocaged nitric oxide
IUCrJ·2025· 1 citedOpen Access
Integrated structural dynamics uncover new modes of B <sub>12</sub> photoreceptor activation
2025Open Access
Mechanism of Nitric Oxide Reduction at Biological Heme Active Sites
ECS Meeting Abstracts·2025
Author response for "Hydration‐coupled allosteric locking of a phenol‐ and zinc‐free bioactive insulin analog"
2025
Deciphering the altered conformational states of bifunctional thaumarchaeal crotonyl-CoA hydratase and 3-hydroxypropionyl-CoA dehydratase from <i>Nitrosopumilus maritimus</i>
2025Open Access
Nitric Oxide Binding to Ferric and Ferrous Porphyrins Encapsulated in the Cyclodextrin Nanocavities in Aqueous Solution
Inorganic Chemistry·2025· 1 cited
Techniques for Characterization of Short-lived Intermediates Appearing in the Catalytic Reaction of Iron-containing Proteins
2025
Capturing structural intermediates in an animal-like cryptochrome photoreceptor by time-resolved crystallography
Science Advances·2025· 4 citedOpen Access
Redox-State-Dependent Structural Changes within a Prokaryotic 6–4 Photolyase
Journal of the American Chemical Society·2025· 2 citedOpen Access
Experimental and Computational Insights into the Structural Dynamics of the Fc Fragment of IgG1 Subtype from Biosimilar VEGF‐Trap
Small Structures·2025Open Access
XFEL crystallography reveals catalytic cycle dynamics during non-native substrate oxidation by cytochrome P450BM3
Communications Chemistry·2025· 1 citedOpen Access
Solubility, Hydration, and Sulphate Coordination in Cubic Insulin Crystals from Esrapid <sup>TM</sup> Monomers Stabilized in Divalent Anionic Form of Citric Acid
2025· 1 citedOpen Access
Double crossed? Structural and computational studies of an unusually crosslinked haem in <i>Methylococcus capsulatus</i> cytochrome P460
Chemical Science·2025Open Access
Double crossed? Structural and computational studies of an unusual crosslinked heme in <i>Methylococcus capsulatus</i> cytochrome P460
2024· 1 citedOpen Access
SSX and SFX probe the cyanobacterial FutA iron binding protein by X-ray induced photoreduction and reveal a switch for Fe<sup>II</sup>/Fe<sup>III</sup> binding
Acta Crystallographica Section A Foundations and Advances·2024Open Access
Experimental and Computational Insights into the Structural Dynamics of the Fc Fragment of IgG1 Subtype from Biosimilar VEGF-Trap
2024Open Access
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Frequent Co-authors

Teizo Kitagawa(16), Yoshitsugu Shiro(13), Elizabeth C. Theil(11), Hiroshi Sugimoto(11), Hideki Furutachi(7), Shuhei Fujinami(7), Masatatsu Suzuki(7), Rabindra K. Behera(5), Keitaro Yamashita(5), Kunio Hirata(5), Shiro Yoshioka(5), Koichiro Ishimori(5), Isao Morishima(5), Tomoya Hino(4), Shingo Nagano(4), Tamao Hisano(4), Shigeki Owada(4), Masaki Yamamoto(4), Minoru Kubo(4), Shigenori Nagatomo(4)