Kristel Sleegers

University of Antwerp — Belgium

Medicine · Health Sciences

81h-index38.9kcitations360works5.52yr avg
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Research Topics

Alzheimer's disease research and treatments(159), Bioinformatics and Genomic Networks(70), Genetic Associations and Epidemiology(61), Dementia and Cognitive Impairment Research(53), Amyotrophic Lateral Sclerosis Research(53)

Publications335 total

Differences and overlaps in TDP-43 pathology of ‘pure’ LATE-NC compared to LATE-NC coexisting with Alzheimer’s disease
Acta Neuropathologica·2025Open Access
Machine learning in Alzheimer’s disease genetics
Nature Communications·2025· 5 citedOpen Access
Alzheimer's disease and its co‐pathologies: Implications for hippocampal degeneration, cognitive decline, and the role of <i>APOE</i> ε4
Alzheimer s & Dementia·2025· 5 citedOpen Access
Analysis of the splicing landscape of the frontal cortex in FTLD-TDP reveals subtype specific patterns and cryptic splicing
Acta Neuropathologica·2025· 3 citedOpen Access
Alzheimer’s disease and its co-pathologies: implications for hippocampal degeneration, cognitive decline, and the role of <i>APOE</i> ε4
2025Open Access
The impact of rare genetic variants on Alzheimer disease
Nature Reviews Neurology·2025· 15 cited
Multiomic analyses direct hypotheses for Creutzfeldt-Jakob disease risk genes
Brain·2025· 7 citedOpen Access
Large‐scale Genome‐wide Investigation of Short Tandem Repeats Associated with Alzheimer’s Disease Risk
Alzheimer s & Dementia·2024Open Access
Genome‐wide investigation of a neuropathological cohort offers novel insights in the genetic risk underlying hallmark and co‐morbid lesions implicated in Alzheimer’s disease
Alzheimer s & Dementia·2024Open Access
Connection between APOE4 and tau is mediated via amyloid‐beta and Alzheimer’s co‐pathologies in human autopsy brains
Alzheimer s & Dementia·2024Open Access
Deciphering a Single‐cell atlas and loss‐of‐function analysis revealing <i>ABCA7</i>’s transcriptome insights in Alzheimer’s disease
Alzheimer s & Dementia·2024Open Access
Discrepancy between Apolipoprotein E genotyping and proteotyping as a result of a nonsense mutation
Alzheimer s & Dementia·2024· 1 citedOpen Access
Hypothesis-based investigation of known AD risk variants reveals the genetic underpinnings of neuropathological lesions observed in Alzheimer’s-type dementia
Acta Neuropathologica·2024· 4 citedOpen Access
Characterizing tandem repeat complexities across long-read sequencing platforms with TREAT and <i>otter</i>
Genome Research·2024· 9 citedOpen Access
The <i>SORL1</i> p.Y1816C variant causes impaired endosomal dimerization and autosomal dominant Alzheimer’s disease
Proceedings of the National Academy of Sciences·2024· 20 citedOpen Access
Scywalker: scalable end-to-end data analysis workflow for long-read single-cell transcriptome sequencing
Bioinformatics·2024· 5 citedOpen Access
Multiomic Analyses Direct Hypotheses for Creutzfeldt-Jakob Disease Risk Genes
2024Open Access
Comparison of plasma soluble and extracellular vesicles-associated biomarkers in Alzheimer’s disease patients and cognitively normal individuals
Alzheimer s Research & Therapy·2024· 7 citedOpen Access
Alteration of gene expression and protein solubility of the PI 5-phosphatase SHIP2 are correlated with Alzheimer’s disease pathology progression
Acta Neuropathologica·2024· 8 citedOpen Access
Paired plasma lipidomics and proteomics analysis in the conversion from mild cognitive impairment to Alzheimer's disease
Computers in Biology and Medicine·2024· 17 citedOpen Access
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Frequent Co-authors

Christine Van Broeckhoven(41), Sebastiaan Engelborghs(27), Marc Cruts(18), Rik Vandenberghe(15), Julie van der Zee(13), Nathalie Brouwers(12), Ilse Gijselinck(12), Karolien Bettens(11), Jean‐Charles Lambert(10), Maria Mattheijssens(10), Karin Peeters(10), Peter P. De Deyn(10), Denise Harold(9), Simon Lovestone(9), Rebecca Sims(8), Florence Pasquier(8), Dominique Campion(8), Marleen Van den Broeck(8), Benjamin Grenier‐Boley(7), Amy Gerrish(7)