José A. Seoane

Hebron University — PS

Biochemistry, Genetics and Molecular Biology · Life Sciences

31h-index6.1kcitations175works1.42yr avg
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Research Topics

Cancer Genomics and Diagnostics(24), Pancreatic and Hepatic Oncology Research(23), Gene expression and cancer classification(23), Cancer Mechanisms and Therapy(23), CRISPR and Genetic Engineering(22)

Publications174 total

Molecular and Clinical Analyses of Gene Fusions Identify Therapeutic Targets in Paired Primary and Metastatic Breast Cancer from the AURORA Program (BIG 14-01)
Clinical Cancer Research·2025
Abstract PR003: Exploring the exposome impact in early-onset colon and rectal cancer using methylation scores
Clinical Cancer Research·2025
Estrogen receptor signaling drives immune evasion and immunotherapy resistance in HR+ breast cancer
Journal of Clinical Investigation·2025· 1 citedOpen Access
Abstract A030: Inactivation of <i>CDKN2A</i> <i>ARF</i> promotes p53-independent remodeling of the PDAC tumor microenvironment
Cancer Research·2025
Epigenetic synthetic lethality as a cancer therapeutic strategy: synergy of experimental and computational approaches
Epigenomics·2025· 1 citedOpen Access
313P Association of CDK12 mutations and trastuzumab deruxtecan (TDxd) administration with overall survival (mOS) in HER2+ mBC
ESMO Open·2025Open Access
AB-617. Retrospective neurophysiologic evaluation of our cohort of GBS and MFS patients. Value of early EMG recordings and patterns of involvement in different subtypes
Clinical Neurophysiology·2025
Exposomal determinants of non-genetic plasticity in tumor initiation
Trends in cancer·2025· 2 cited
Multimodal data integration in early-stage breast cancer
The Breast·2025· 8 citedOpen Access
Transcriptomic signature reveals sensitivity to tubulin inhibitors in colon cancer
2025Open Access
Advances in the approaches used to repurpose drugs for neuroblastoma
Expert Opinion on Drug Discovery·2024· 3 cited
341MO Impact of aging on the genetic and transcriptional landscape of advanced breast cancer: an AURORA program (BIG 14-01) subanalysis
Annals of Oncology·2024Open Access
Epigenetic Fingerprints Link Early-Onset Colon and Rectal Cancer to Pesticide Exposure
2024Open Access
Abstract PS17-04: Clinical and Genomic Features of ER-Positive/HER2-negative Metastatic Breast Cancer in AURORA Molecular Screening Initiative (BIG 14-01): Mechanisms of Endocrine Therapy Resistance and Implications for Adjuvant Approaches
Cancer Research·2024
Abstract PO2-16-02: RBsig gene-expression signature in patients with endocrine resistant metastatic breast cancer treated with palbociclib and fulvestrant in the PYTHIA trial
Cancer Research·2024Open Access
Epigenetic Control of Cancer Cell Dormancy and Awakening in Endocrine Therapy Resistance
Cancer Discovery·2024· 8 citedOpen Access
Functional screening of amplification outlier oncogenes in organoid models of early tumorigenesis
Cell Reports·2023· 10 citedOpen Access
p53 governs an AT1 differentiation programme in lung cancer suppression
Nature·2023· 77 citedOpen Access
Molecular classification and biomarkers of clinical outcome in breast ductal carcinoma in situ: Analysis of TBCRC 038 and RAHBT cohorts
Cancer Cell·2023· 3 citedOpen Access
Clinico-molecular characteristics associated with outcomes in breast cancer patients treated with CDK4/6 inhibitors: Results from the AURORA Molecular Screening Initiative.
Journal of Clinical Oncology·2023· 7 cited
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Frequent Co-authors

Christina Curtis(22), Julián Dorado(12), Cristian R. Munteanu(9), Alejandro Pazos(8), Laura D. Attardi(5), Carlos Fernández-Lozano(5), Vanessa Aguiar‐Pulido(5), Peter K. Jackson(4), Monte M. Winslow(4), Michael C. Bassik(4), Daniel Rivero(4), Nitin Raj(4), Alyssa M. Kaiser(4), Mengxiong Wang(4), Tom R. Gaunt(4), Juan R. Rabuñal(4), Ina Felau(3), Jean C. Zenklusen(3), Peter W. Laird(3), Howard Y. Chang(3)