Xiangsheng Huang

The University of Texas Health Science Center — United States

Immunology and Microbiology · Life Sciences

17h-index3.3kcitations50works2.82yr avg
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Research Topics

Immune Cell Function and Interaction(14), Gut microbiota and health(11), Drug Transport and Resistance Mechanisms(8), IL-33, ST2, and ILC Pathways(8), Immune Response and Inflammation(6)

Publications50 total

miR-27a expression during inflammatory organ injury associated with ARDS and a novel tissue-specific knockout model
Genes & Diseases·2025Open Access
miR147 promotes mucosal integrity and healing in intestinal inflammation
JCI Insight·2025Open Access
Microbial imprints on colorectal cancer: the epigenetic silencing of PHLPP1 as a prognostic nexus
BMJ Oncology·2025Open Access
Editorial: Immunoregulation by adenosine signaling in infection and inflammation
Frontiers in Cell and Developmental Biology·2025Open Access
HIF-2α-dependent induction of miR-29a restrains TH1 activity during T cell dependent colitis
Nature Communications·2024· 14 citedOpen Access
Cooperative activation of PDK1 and AKT by MAPK4 enhances cancer growth and resistance to therapy
PLoS Biology·2023· 11 citedOpen Access
Bile acid conditioned Dendritic cells through FXR and specialize T cell function in the ileum
The Journal of Immunology·2023· 1 citedOpen Access
A phospholipid mimetic targeting LRH-1 ameliorates colitis
Cell chemical biology·2022· 15 citedOpen Access
CAR directs T cell adaptation to bile acids in the small intestine
Nature·2021· 78 citedOpen Access
Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity
Nature Communications·2020· 958 citedOpen Access
Tapping into a phospholipid-LRH-1 axis yields a powerful anti-inflammatory agent with in vivo activity against colitis
2020· 1 cited
A novel phospholipid mimetic targeting LRH-1 ameliorates colitis
2020· 1 citedOpen Access
IL-21 Promotes Intestinal Memory IgA Responses
The Journal of Immunology·2020· 17 citedOpen Access
479 PRO-INFLAMMATORY DRIVEN REACTIVE OXYGEN SPECIES IS SUPPRESSED BY LACTOBACILLUS REUTERI IN VITRO IN HUMAN INTESTINAL EPITHELIAL CELLS AND IN VIVO IN MOUSE COLITIS MODELS
Gastroenterology·2020
Short chain fatty acids regulate T cell metabolism to promote IL-22 production and gut immunity
The Journal of Immunology·2020· 1 cited
Development of the First Low Nanomolar Liver Receptor Homolog-1 Agonist through Structure-guided Design
Journal of Medicinal Chemistry·2019· 31 citedOpen Access
Development of the first low nanomolar Liver Receptor Homolog-1 agonist through structure-guided design
2019· 3 citedOpen Access
Microbiota Metabolite Short-Chain Fatty Acids Facilitate Mucosal Adjuvant Activity of Cholera Toxin through GPR43
The Journal of Immunology·2019· 58 citedOpen Access
Microbiota metabolites SCFA stimulate epithelial migration to promote wound healing through MFGE8 and PAK1
The Journal of Immunology·2019· 4 cited
376 – Interleukin-33 Promotes Reg3G Expression in Intestinal Epithelial Cells and Regulates Gut Microbiota
Gastroenterology·2019
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Frequent Co-authors

Suxia Yao(20), Feidi Chen(12), Yi Xiao(12), Anthony J. Bilotta(11), Yingzi Cong(11), Mingming Sun(11), Yingzi Cong(10), Zhanju Liu(9), Wenjing Yang(8), Peter T. Soboslay(8), David D. Moore(7), Leiqi Xu(6), Liang Chen(6), Chunyan Ma(6), Wenjing Yang(6), Sara M. Dann(5), Wei Wu(5), Guohui Wang(5), Suzanne G. Mays(5), Autumn R. Flynn(5)