Kottarappat N. Dileepan

University of Kansas Medical Center — United States

Immunology and Microbiology · Life Sciences

24h-index2.8kcitations86works0.02yr avg
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Research Topics

Mast cells and histamine(33), Receptor Mechanisms and Signaling(14), Inflammatory mediators and NSAID effects(12), Asthma and respiratory diseases(10), Atherosclerosis and Cardiovascular Diseases(9)

Publications86 total

Mast cell-mediated immune regulation in health and disease
Frontiers in Medicine·2023· 77 citedOpen Access
Mast Cell Degranulation Decreases Lipopolysaccharide-Induced Aortic Gene Expression and Systemic Levels of Interleukin-6 <i>In Vivo</i>
Mediators of Inflammation·2019· 3 citedOpen Access
THU0506 MAST CELL DEFICIENCY AMPLIFIES INFLAMMATORY RESPONSE IN A MOUSE MODEL OF KAWASAKI'S DISEASE
Annals of the Rheumatic Diseases·2019Open Access
221. MAST CELL DEFICIENCY LEADS TO DYSREGULATION OF IL-6 AND INF-Γ HOMOEOSTASIS IN CAWS-INDUCED SYSTEMIC VASCULITIS MOUSE MODEL
Lara D. Veeken·2019Open Access
Intravenous Cocaine Results in an Acute Decrease in Levels of Biomarkers of Vascular Inflammation in Humans
Cardiovascular Toxicology·2018· 9 cited
Protective Role of Mast Cells in Primary Systemic Vasculitis: A Perspective
Frontiers in Immunology·2017· 8 citedOpen Access
SAT0355 Inhibition of Human Aortic Endothelial IL-6 Levels by Candida Albicans Water-Soluble Fraction (CAWS)
Annals of the Rheumatic Diseases·2016
Synergistic Amplification of Lipopolysaccharide‐ and Histamine‐induced TLR4 and COX2 Expression by Cigarette Smoke Extract and Nicotine in Endothelial Cells
The FASEB Journal·2016· 1 cited
Mast Cell: A Multi-Functional Master Cell
Frontiers in Immunology·2016· 860 citedOpen Access
Cigarette Smoke Amplifies Inflammatory Response and Atherosclerosis Progression Through Activation of the H1R-TLR2/4-COX2 Axis
Frontiers in Immunology·2015· 51 citedOpen Access
Early Effects of Hypervitaminosis A on Hepatic Gluconeogenesisl
World review of nutrition and dietetics·2015· 1 cited
Mast Cells Distinctly Regulate Inflammatory Response in Wild‐type and H1R Null Mice
The FASEB Journal·2015
Chronic Ingestion of H1-Antihistamines Increase Progression of Atherosclerosis in Apolipoprotein E-/- Mice
PLoS ONE·2014· 22 citedOpen Access
OP0138 Novel Role of Mast Cells in the Regulation of Large Vessel Vasculitis
Annals of the Rheumatic Diseases·2014· 1 cited
H1-antihistamines exacerbate high-fat diet-induced hepatic steatosis in wild-type but not in apolipoprotein E knockout mice
American Journal of Physiology-Gastrointestinal and Liver Physiology·2014· 20 citedOpen Access
H1‐antihistamines exacerbate high fat diet‐induced fatty liver disease in wild type but not in apolipoprotein E‐knockout mice (1116.10)
The FASEB Journal·2014
Combinatorial treatment with epigenetic modifiers inhibits thrombin‐induced eNOS/RhoA signaling and restores AJ integrity (1176.7)
The FASEB Journal·2014
Overexpression of Toll‐like receptor‐2 in human carotid artery plaques reflects clinical severity of atherosclerosis
The FASEB Journal·2013· 1 cited
Mast cell deficiency attenuates progression of atherosclerosis and hepatic steatosis in apolipoprotein E-null mice
American Journal of Physiology-Heart and Circulatory Physiology·2012· 43 citedOpen Access
Stimulation of Cyclooxygenase‐2 (COX2) Pathway in Human Coronary Artery Endothelial Cells by Histamine Involves ERK and p38 activation but not Early Growth Response Factor‐1 (EGR1)
The FASEB Journal·2012
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Frequent Co-authors

Daniel J. Stechschulte(27), Yuai Li(10), Vineesh V. Raveendran(8), Xiaoyu Tan(6), Donald D. Smith(5), S.R. Wagle(5), Virginia J. Savin(4), Jaya Talreja(4), Mukut Sharma(4), Ossama Tawfik(4), Luqi Chi(3), Ram Kumar Sharma(3), Mohammad Humayun Kabir(3), Ram Sharma(3), Ellen T. McCarthy(2), Lisa Stehno‐Bittel(2), Karen Simpson(2), David M. Segal(2), Rajat S. Barua(2), Ginger L. Milne(2)