Jeanette H.W. Leusen

Utrecht University — Netherlands

Medicine · Health Sciences

51h-index7.7kcitations266works2.82yr avg
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Research Topics

Monoclonal and Polyclonal Antibodies Research(157), Glycosylation and Glycoproteins Research(72), T-cell and B-cell Immunology(46), Immune Cell Function and Interaction(42), HER2/EGFR in Cancer Research(38)

Publications266 total

Quantification of Signal Transduction Pathway Activity in Pancreatic Ductal Adenocarcinoma
International Journal of Molecular Sciences·2025Open Access
Preclinical assessment of two FcγRI-specific antibodies that competitively inhibit immune complex-FcγRI binding to suppress autoimmune responses
Nature Communications·2025Open Access
IgM Anti-Ganglioside Binding and Complement Activation in an iPSC-Derived Motor Neuron Model for Multifocal Motor Neuropathy
Neurology Neuroimmunology & Neuroinflammation·2025Open Access
Retargeted adenoviruses for local IgA and CD47 blocker production as a novel cancer therapy
2025Open Access
Extracellular domain 1 of human FcγRI (CD64) identified as the binding site for anti-FcγRI antibodies
mAbs·2025Open Access
Targeting C2 reduces ischemia-reperfusion injury-induced complement activation in preclinical human models
2025Open Access
High-plex imaging of hepatoblastoma and adjacent liver in pediatric patients reveals a predominant myeloid infiltrate expressing immune-checkpoints
Cancer Immunology Immunotherapy·2025Open Access
Anti-PD-1 treatment response is associated with the influx of circulating myeloid and T-cell subsets into the metastatic melanoma tumor microenvironment
British Journal of Cancer·2025· 1 citedOpen Access
Myeloid cell-mediated killing of B-ALL by CD38 and CD20 IgA antibody variants is enhanced by CD47/SIRPα interference
2025Open Access
Treatment of colorectal peritoneal metastases with oxaliplatin induces biomarkers predicting response to immune checkpoint blockade
Translational Oncology·2025· 1 citedOpen Access
Maternal Dietary Fiber Intake During Lactation and Human Milk Oligosaccharide Fucosylation: a PRIMA Birth Cohort Study
Molecular Nutrition & Food Research·2025Open Access
The Efficacy of Targeted Monoclonal IgA Antibodies Against Pancreatic Ductal Adenocarcinoma
Cells·2025· 1 citedOpen Access
<i>Complement</i>ing CD20 antibodies’ effector functions
Blood·2025Open Access
Development and validation of a high throughput multiplex immunofluorescence assay to detect all human immunoglobulin isotypes and subclasses in human fluids
The Journal of Immunology·2025Open Access
Engineering of anticancer human immunoglobulin A equipped with albumin for enhanced plasma half-life
PNAS Nexus·2025· 3 citedOpen Access
Sialylation inhibition improves macrophage mediated tumor cell phagocytosis of breast cancer cells triggered by therapeutic antibodies of different isotypes
Frontiers in Oncology·2024· 7 citedOpen Access
Complement activation by <scp>IgM</scp> autoantibodies linked to immune‐mediated neuropathies depends on <scp>C2</scp>
European Journal of Neurology·2024· 3 citedOpen Access
The relevance of tumor target expression levels on IgA-mediated cytotoxicity in cancer immunotherapy
Cancer Immunology Immunotherapy·2024· 5 citedOpen Access
Supplementary Figure 3 from Enhancing Neutrophil Cytotoxicity of a Panel of Clinical EGFR Antibodies by Fc Engineering to IgA3.0
2024Open Access
Supplementary Figure 1 from Enhancing Neutrophil Cytotoxicity of a Panel of Clinical EGFR Antibodies by Fc Engineering to IgA3.0
2024Open Access
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Frequent Co-authors

Jan G. J. van de Winkel(14), J.H. Marco Jansen(10), Péter Boross(9), Dirk Roos(7), Maaike Nederend(7), Thomas Valerius(7), Paul W.H.I. Parren(5), Mitchell Evers(5), P. M. Hilarius(4), Saskia Meyer(4), Hanke L. Matlung(3), Katka Franke(3), Taco W. Kuijpers(3), Timo K. van den Berg(3), Arianne M. Brandsma(3), Cees E. van der Poel(3), Thies Rösner(3), Toine ten Broeke(3), J. Sjef Verbeek(3), Stefan Lohse(3)