Jennifer L. McCann

University of Minnesota — United States

Immunology and Microbiology · Life Sciences

18h-index1.6kcitations39works0.02yr avg
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Research Topics

HIV Research and Treatment(8), CRISPR and Genetic Engineering(8), Polyomavirus and related diseases(6), Epigenetics and DNA Methylation(5), Genomics and Chromatin Dynamics(4)

Publications39 total

APOBEC3B regulates R-loops and promotes transcription-associated mutagenesis in cancer
Nature Genetics·2023· 70 citedOpen Access
Data from The PKC/NF-κB Signaling Pathway Induces APOBEC3B Expression in Multiple Human Cancers
2023Open Access
Supplementary Figures S1 through S6 and Supplementary Tables S1 and S2 from The PKC/NF-κB Signaling Pathway Induces APOBEC3B Expression in Multiple Human Cancers
2023Open Access
Data from The PKC/NF-κB Signaling Pathway Induces APOBEC3B Expression in Multiple Human Cancers
2023Open Access
Supplementary Figures S1 through S6 and Supplementary Tables S1 and S2 from The PKC/NF-κB Signaling Pathway Induces APOBEC3B Expression in Multiple Human Cancers
2023Open Access
R-loop homeostasis and cancer mutagenesis promoted by the DNA cytosine deaminase APOBEC3B
2021· 14 citedOpen Access
Structural basis for recognition of distinct deaminated DNA lesions by endonuclease Q
Proceedings of the National Academy of Sciences·2021· 23 citedOpen Access
The ARF tumor suppressor targets PPM1G/PP2Cγ to counteract NF-κB transcription tuning cell survival and the inflammatory response
Proceedings of the National Academy of Sciences·2020· 18 citedOpen Access
Characterization of the mechanism by which the RB/E2F pathway controls expression of the cancer genomic DNA deaminase APOBEC3B
eLife·2020· 35 citedOpen Access
Functional and Structural Insights into a Vif/PPP2R5 Complex Elucidated Using Patient HIV-1 Isolates and Computational Modeling
Journal of Virology·2020· 19 citedOpen Access
Author response: Characterization of the mechanism by which the RB/E2F pathway controls expression of the cancer genomic DNA deaminase APOBEC3B
2020· 2 citedOpen Access
KAP1 Recruitment of the 7SK snRNP Complex to Promoters Enables Transcription Elongation by RNA Polymerase II
UNC Libraries·2020Open Access
MagnEdit—interacting factors that recruit DNA-editing enzymes to single base targets
Life Science Alliance·2020· 10 citedOpen Access
HIV-1 Vif Triggers Cell Cycle Arrest by Degrading Cellular PPP2R5 Phospho-regulators
Cell Reports·2019· 49 citedOpen Access
Quantifying Renal And Tumor Doses with Individualized Dosimetry In 177Lu DOTATATE Therapy – What Difference Does It Make?
International Journal of Radiation Oncology*Biology*Physics·2019Open Access
Regulation Of Apobec3B Via Interacting Proteins
University of Minnesota Digital Conservancy (University of Minnesota)·2019Open Access
The DNA deaminase APOBEC3B interacts with the cell-cycle protein CDK4 and disrupts CDK4-mediated nuclear import of Cyclin D1
Journal of Biological Chemistry·2019· 24 citedOpen Access
Polyomavirus T Antigen Induces <i>APOBEC3B</i> Expression Using an LXCXE-Dependent and TP53-Independent Mechanism
mBio·2019· 42 citedOpen Access
Epstein–Barr virus BORF2 inhibits cellular APOBEC3B to preserve viral genome integrity
Nature Microbiology·2018· 136 cited
Genetic and mechanistic basis for APOBEC3H alternative splicing, retrovirus restriction, and counteraction by HIV-1 protease
Nature Communications·2018· 33 citedOpen Access
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Frequent Co-authors

Reuben S. Harris(24), Gabriel J. Starrett(13), Daniel J. Salamango(11), William L. Brown(11), Michael A. Carpenter(9), Rebecca M. McDougle(9), Matthew C. Jarvis(8), Emily K. Law(7), Brandon Leonard(7), Leah Kosyakovsky(7), Michael B. Burns(7), Elizabeth M. Luengas(6), Peter J. Parker(6), Nadine M. Shaban(5), Özlem Demir(5), Rommie E. Amaro(5), Amy M. Molan(5), Diako Ebrahimi(4), Nuri A. Temiz(4), Iván D’Orso(4)