Umesh C. Karandikar

Baylor College of Medicine — United States

Medicine · Health Sciences

20h-index3.1kcitations43works8.02yr avg
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Research Topics

Viral gastroenteritis research and epidemiology(17), Developmental Biology and Gene Regulation(11), Retinal Development and Disorders(7), Animal Virus Infections Studies(6), Genomics and Chromatin Dynamics(5)

Publications43 total

Comparative effects of combustible cigarette versus electronic cigarette exposures on KRAS mutant lung cancer promotion
Neoplasia·2025Open Access
A novel system to culture human intestinal organoids under physiological oxygen content to study microbial-host interaction
PLoS ONE·2024· 16 citedOpen Access
Rotavirus-mediated DGAT1 degradation: A pathophysiological mechanism of viral-induced malabsorptive diarrhea
Proceedings of the National Academy of Sciences·2023· 13 citedOpen Access
Abstract 649: Comparative effects of combustible cigarette versus electronic cigarette exposures on K-ras mutant lung cancer
Cancer Research·2023
CLIC and membrane wound repair pathways enable pandemic norovirus entry and infection
Nature Communications·2023· 47 citedOpen Access
Effect of substrate stiffness on human intestinal enteroids’ infectivity by enteroaggregative Escherichia coli
Acta Biomaterialia·2021· 13 citedOpen Access
Effect of Substrate Stiffness on Human Intestinal Enteroids Infectivity by Enteroaggregative Escherichia coli
2021Open Access
Enteroaggregative E. coli Adherence to Human Heparan Sulfate Proteoglycans Drives Segment and Host Specific Responses to Infection
PLoS Pathogens·2020· 37 citedOpen Access
Human norovirus exhibits strain-specific sensitivity to host interferon pathways in human intestinal enteroids
Proceedings of the National Academy of Sciences·2020· 98 citedOpen Access
588 GII.3 HUMAN NOROVIRUS REQUIRES BILE ACID AND CERAMIDE FOR ENTRY AND INFECTION OF HUMAN INTESTINAL ENTEROIDS
Gastroenterology·2020
Genetic Manipulation of Human Intestinal Enteroids Demonstrates the Necessity of a Functional Fucosyltransferase 2 Gene for Secretor-Dependent Human Norovirus Infection
mBio·2020· 108 citedOpen Access
Bile acids and ceramide overcome the entry restriction for GII.3 human norovirus replication in human intestinal enteroids
Proceedings of the National Academy of Sciences·2020· 115 citedOpen Access
Sperm Flagellar 1 Binds Actin in Intestinal Epithelial Cells and Contributes to Formation of Filopodia and Lamellipodia
Gastroenterology·2019· 8 citedOpen Access
Two- and Three-Dimensional Bioengineered Human Intestinal Tissue Models for Cryptosporidium
Methods in molecular biology·2019· 32 citedOpen Access
Human Norovirus Cultivation in Nontransformed Stem Cell-Derived Human Intestinal Enteroid Cultures: Success and Challenges
Viruses·2019· 131 citedOpen Access
3 – A New Form of Human Rotavirus Produced from Human Intestinal Enteroids
Gastroenterology·2019Open Access
Human intestinal enteroids with inducible neurogenin-3 expression as a novel model of gut hormone secretion
2019· 4 citedOpen Access
Human Intestinal Enteroids With Inducible Neurogenin-3 Expression as a Novel Model of Gut Hormone Secretion
Cellular and Molecular Gastroenterology and Hepatology·2019· 82 citedOpen Access
Gastrointestinal microphysiological systems
Experimental Biology and Medicine·2017· 37 citedOpen Access
A paradox of transcriptional and functional innate interferon responses of human intestinal enteroids to enteric virus infection
Proceedings of the National Academy of Sciences·2017· 125 citedOpen Access
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Frequent Co-authors

Mary K. Estes(24), Sue E. Crawford(13), Khalil Ettayebi(11), Sarah E. Blutt(11), Xi‐Lei Zeng(11), Ashok P. Bidwai(11), Sasirekha Ramani(9), Robert L. Atmar(8), Clifton P. Bishop(8), Victoria R. Tenge(7), James R. Broughman(6), Frederick H. Neill(6), B. Vijayalakshmi Ayyar(6), Kosuke Murakami(5), David Y. Graham(5), Nicholas C. Zachos(5), Mark Donowitz(5), Shih‐Ching Lin(5), Graeme Mardon(5), Kapil Saxena(4)