Chad Brocker

United States Food and Drug Administration — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

35h-index7.0kcitations59works2.02yr avg
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Research Topics

Peroxisome Proliferator-Activated Receptors(18), Metabolomics and Mass Spectrometry Studies(9), Adipose Tissue and Metabolism(8), Drug Transport and Resistance Mechanisms(6), Cancer, Hypoxia, and Metabolism(6)

Publications59 total

On‐Chip Reconstitution of Uniformly Shear‐Sensing 3D Matrix‐Embedded Multicellular Blood Microvessel (Adv. Funct. Mater. 10/2024)
Advanced Functional Materials·2024· 2 citedOpen Access
On‐Chip Reconstitution of Uniformly Shear‐Sensing 3D Matrix‐Embedded Multicellular Blood Microvessel
Advanced Functional Materials·2023· 14 citedOpen Access
Long non-coding RNA G23Rik attenuates fasting-induced lipid accumulation in mouse liver
Molecular and Cellular Endocrinology·2022· 8 citedOpen Access
Long non-coding RNA G23Rik attenuates fasting-induced lipid accumulation in the liver
2022Open Access
Gene repression through epigenetic modulation by PPARA enhances hepatocellular proliferation
iScience·2022· 35 citedOpen Access
Feedback repression of PPARα signaling by Let-7 microRNA
Cell Reports·2021· 19 citedOpen Access
Long non-coding RNA Gm15441 attenuates hepatic inflammasome activation in response to PPARA agonism and fasting
Nature Communications·2020· 99 citedOpen Access
Metabolomic profiling of metoprolol hypertension treatment reveals altered gut microbiota-derived urinary metabolites
Human Genomics·2020· 33 citedOpen Access
Dietary Intake Regulates the Circulating Inflammatory Monocyte Pool
Cell·2019· 425 citedOpen Access
Long non-coding RNA Gm15441 attenuates hepatic inflammasome activation in response to metabolic stress
2019· 3 citedOpen Access
Hepatocyte peroxisome proliferator-activated receptor α regulates bile acid synthesis and transport
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids·2019· 52 cited
Intestinal PPARα Protects Against Colon Carcinogenesis via Regulation of Methyltransferases DNMT1 and PRMT6
Gastroenterology·2019· 146 citedOpen Access
Dietary intake regulates the circulating inflammatory monocyte pool
2019· 33 citedOpen Access
Keratin 23 Is a Peroxisome Proliferator‐Activated Receptor Alpha–Dependent, MYC‐Amplified Oncogene That Promotes Hepatocyte Proliferation
Hepatology·2019· 46 citedOpen Access
Table of Contents
American Journal Of Pathology·2019Open Access
Hepatocyte Peroxisome Proliferator–Activated Receptor α Enhances Liver Regeneration after Partial Hepatectomy in Mice
American Journal Of Pathology·2018· 33 citedOpen Access
REVERBa couples the circadian clock to hepatic glucocorticoid action
Journal of Clinical Investigation·2018· 79 citedOpen Access
Extrahepatic PPARα modulates fatty acid oxidation and attenuates fasting-induced hepatosteatosis in mice
Journal of Lipid Research·2018· 81 citedOpen Access
Corrigendum to “Metabolic adaptation to intermittent fasting is independent of peroxisome proliferator-activated receptor alpha” [Mol Metab 7 (2018) 80–89]
Molecular Metabolism·2018· 4 citedOpen Access
Hepatic peroxisome proliferator‐activated receptor alpha mediates the major metabolic effects of Wy‐14643
Journal of Gastroenterology and Hepatology·2017· 26 citedOpen Access
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Frequent Co-authors

Frank J. Gonzalez(28), Vasilis Vasiliou(18), Kristopher W. Krausz(14), Cen Xie(10), Donghwan Kim(9), Tingting Yan(7), Guolin Li(6), Daniel W. Nebert(6), Shogo Takahashi(6), Aijuan Qu(5), Tomoki Yagai(5), Rong Xiang(4), Moshe Levi(4), Satori A. Marchitti(3), Andrew D. Patterson(3), Ying Chen(3), Brian C. Jackson(3), David C. Thompson(3), Changtao Jiang(3), David C. Thompson(3)