Benoit Vanasse

Sanofi (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

11h-index388citations26works0.02yr avg
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Research Topics

Chemical Synthesis and Analysis(9), Asymmetric Synthesis and Catalysis(7), Oxidative Organic Chemistry Reactions(6), Carbohydrate Chemistry and Synthesis(5), Synthetic Organic Chemistry Methods(4)

Publications26 total

Scale-Up of an Enantioselective Overman Rearrangement for an Asymmetric Synthesis of a Glycine Transporter 1 Inhibitor
Organic Process Research & Development·2012· 11 cited
Process Development of Selectively Benzoylated and Fluorinated Glycosyl Donors
Organic Process Research & Development·2010· 16 cited
Process research toward scale-up and industrial preparation of RPR 109891 (Klerval™)
Kluwer Academic Publishers eBooks·2006
Diastereoselective Alkylation of β-Amino Esters:  Structural and Rate Studies Reveal Alkylations of Hexameric Lithium Enolates
Journal of the American Chemical Society·2004· 52 cited
Characterization of β-Amino Ester Enolates as Hexamers via <sup>6</sup>Li NMR Spectroscopy
Journal of the American Chemical Society·2004· 30 cited
CCDC 231371: Experimental Crystal Structure Determination
The Cambridge Structural Database·2004Open Access
Diastereoselective alkylation of beta-amino esters Solution structures and proposed mechanism
Abstracts of Papers American Chemical Society·2002
Vanadyl Trichloride
Encyclopedia of Reagents for Organic Synthesis·2001
Vanadium(II) Chloride
Encyclopedia of Reagents for Organic Synthesis·2001
Vanadium(IV) Chloride
Encyclopedia of Reagents for Organic Synthesis·2001· 1 cited
Vanadyl Trifluoride
Encyclopedia of Reagents for Organic Synthesis·2001
Asymmetric processes in the large-scale preparation of chiral drug candidates.
PubMed·2000· 11 cited
Synthesis of novel inhibitors of the HIV-1 protease: Difunctional enols of simple N-protected amino acids
Bioorganic & Medicinal Chemistry·1994· 6 cited
ChemInform Abstract: Highly Stereocontrolled Syntheses of 2,3‐Disubstituted 1,4‐ Butyrolactones Using Ionic and Free Radical Reactions.
ChemInform·1994
ChemInform Abstract: Novel Access to (3R)‐ and (3S)‐3‐Hydroxy‐L‐aspartic Acids, (4S)‐4‐ Hydroxy‐L‐glutamic Acid, and Related Amino Acids.
ChemInform·1994
Highly stereocontrolled syntheses of 2,3-disubstituted 1,4-butyrolactones using ionic and free radical reactions
Canadian Journal of Chemistry·1993· 16 cited
Novel access to (3<i>R</i>)- and (3<i>S</i>)-3-hydroxy-<scp>L</scp>-aspartic acids, (4<i>S</i>)-4-hydroxy- <scp>L</scp>-glutamic acid, and related amino acids
Canadian Journal of Chemistry·1993· 51 cited
Difunctional enols of N-protected amino acids as low molecular weight and novel inhibitors of HIV-1 protease.
Bioorganic & Medicinal Chemistry Letters·1993· 12 cited
ChemInform Abstract: The Stereocontrolled Synthesis of (2S,3R)‐3‐Alkyl‐L‐aspartic Acids Using a 2‐Azetidinone Framework as a Chiral Template.
ChemInform·1992
The Stereocontrolled Synthesis of (2<i>S</i>,3<i>R</i>)-3-Alkyl-L-aspartic Acids Using a 2-Azetidinone Framework as a Chiral Template
Synlett·1992· 32 cited
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Frequent Co-authors

Stephen Hanessian(8), Michael K. O’Brien(6), Sithamalli V. Chandramouli(5), Anne J. McNeil(4), David B. Collum(4), Timothy A. Ayers(4), Gilman E. S. Toombes(3), Emil B. Lobkovsky(3), Matthew R. Powers(3), Teng Jiam Liak(2), Sol M. Grüner(2), Kenzo Sumi(2), John A. Marohn(2), Robert E. Ireland(2), Wolfgang Miltz(2), Clive Pemberton(2), Marco Alpegiani(2), Marc Vaillancourt(2), Éric A. Cohen(2), Geoffrey A. D’Netto(2)