Richard G. Pestell

Baruch S. Blumberg Institute — United States

Medicine · Health Sciences

139h-index69.5kcitations821works190.72yr avg
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Research Topics

Cancer-related Molecular Pathways(170), Epigenetics and DNA Methylation(84), Caveolin-1 and cellular processes(72), Prostate Cancer Treatment and Research(71), Metabolism, Diabetes, and Cancer(69)

Publications814 total

Abstract B062: Leronlimab is associated with long-term survival in metastatic TNBC: Enhancing PD-L1 expression, ICI response, and modulates T cell exhaustion
Cancer Immunology Research·2026
Leronlimab Inhibits Colon Carcinoma Metastasis in a Humanized Mouse Xenograft Model
Preprints.org·2025Open Access
Burden of Central Nervous System Cancer in the United States, 1990-2021
JAMA Neurology·2025Open Access
Abstract B019: CCR5 inhibition with leronlimab is associated with enhanced PD-L1 expression, ICI response, and long-term survival in metastatic TNBC.
Cancer Immunology Research·2025
PPARγ acetylation governs mammary adenocarcinoma tumor growth via acetylated residues that determine DNA sequence-specific binding
Oncogene·2025Open Access
Targeting WEE1 Kinase for Breast Cancer Therapeutics: An Update
International Journal of Molecular Sciences·2025· 2 citedOpen Access
Towards a Unified Framework for Determining Conformational Ensembles of Disordered Proteins
arXiv (Cornell University)·2025Open Access
α-synuclein expression in glioblastoma restores tumor suppressor function and rescues temozolomide drug resistance
Cell Death and Disease·2025· 1 citedOpen Access
Role of GPCR Signaling in Anthracycline-Induced Cardiotoxicity
Cells·2025· 3 citedOpen Access
Editorial Expression of Concern: Role of BRCA1 in heat shock response
Oncogene·2024Open Access
Abstract 5581: The DACH1 gene, frequently co-deleted with BRCA2 in prostate cancer, governs PARP inhibitor resistance
Cancer Research·2024
Abstract 261: Akt1 and Cyclin D1 govern polarity of self-renewing divisions in breast cancer stem cells
Cancer Research·2024
Abstract 1634: Cyclin D1 induces Akt1 activity in RB deficient prostate cancer
Cancer Research·2024
Abstract 3582: PPAR gamma acetylation governs mammary adenocarcinoma tumor growth via acetylated residues that determine DNA sequence-specific binding
Cancer Research·2024
A cyclin D1 intrinsically disordered domain accesses modified histone motifs to govern gene transcription
Oncogenesis·2024· 6 citedOpen Access
The Role and Therapeutic Targeting of CCR5 in Breast Cancer
Cells·2023· 19 citedOpen Access
Endogenous Cyclin D1 Promotes the Rate of Onset and Magnitude of Mitogenic Signaling via Akt1 Ser473 Phosphorylation
Cell Reports·2023· 1 citedOpen Access
The DACH1 gene is frequently deleted in prostate cancer, restrains prostatic intraepithelial neoplasia, decreases DNA damage repair, and predicts therapy responses
Oncogene·2023· 5 citedOpen Access
Regulation of ERα-dependent breast cancer metastasis by a miR-29a signaling
Journal of Experimental & Clinical Cancer Research·2023· 21 citedOpen Access
Abstract 2598: The <i>DACH1</i> gene is frequently deleted in prostate cancer, restrains prostatic intraepithelial neoplasia, augments DNA damage repair and predicts therapy responses
Cancer Research·2023
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Frequent Co-authors

Michael P. Lisanti(23), Chris Albanese(14), Federica Sotgia(14), Ubaldo Martinez‐Outschoorn(13), Stephanos Pavlides(10), Anthony Howell(10), Diana Whitaker‐Menezes(8), Neal Flomenberg(8), Maofu Fu(8), Agnieszka K. Witkiewicz(6), Chenguang Wang(6), Toshiyuki Sakamaki(5), Mark D’Amico(4), Saijun Fan(4), Zhao Lin(4), Philipp E. Scherer(4), Adam Ertel(4), Philippe G. Frank(3), Zhiping Li(3), Aristotelis Tsirigos(3)