Frederick A. Valeriote

Henry Ford Health System — United States

Medicine · Health Sciences

48h-index6.6kcitations222works0.32yr avg
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Research Topics

Microbial Natural Products and Biosynthesis(57), Marine Sponges and Natural Products(53), Cancer therapeutics and mechanisms(25), Synthetic Organic Chemistry Methods(24), Chemical Synthesis and Analysis(18)

Publications221 total

Supplementary Data from Daclatasvir, an Antiviral Drug, Downregulates Tribbles 2 Pseudokinase and Resensitizes Enzalutamide-Resistant Prostate Cancer Cells
2025Open Access
Majusculamide-o, a simplified marine natural product analog, exhibits potent and specific cancer cell cytotoxicity
Scientific Reports·2025Open Access
Further Probing the Properties of a Unique Sponge-derived Alkaloid Through the Isolation of a New (−)-(5<i>E</i>)-(8<i>R</i>)-(14<i>Z</i>)-Mycothiazole Analogue
Journal of Natural Products·2024· 1 citedOpen Access
Novel Small Molecule, UTS-1401, as a Radioprotector for Total-Body Irradiation
Radiation Research·2024
Supplementary Data from Daclatasvir, an Antiviral Drug, Downregulates Tribbles 2 Pseudokinase and Resensitizes Enzalutamide-Resistant Prostate Cancer Cells
2023Open Access
Data from Daclatasvir, an Antiviral Drug, Downregulates Tribbles 2 Pseudokinase and Resensitizes Enzalutamide-Resistant Prostate Cancer Cells
2023Open Access
Data from Daclatasvir, an Antiviral Drug, Downregulates Tribbles 2 Pseudokinase and Resensitizes Enzalutamide-Resistant Prostate Cancer Cells
2023Open Access
Supplementary Data from Daclatasvir, an Antiviral Drug, Downregulates Tribbles 2 Pseudokinase and Resensitizes Enzalutamide-Resistant Prostate Cancer Cells
2023Open Access
Daclatasvir, an Antiviral Drug, Downregulates Tribbles 2 Pseudokinase and Resensitizes Enzalutamide-Resistant Prostate Cancer Cells
Molecular Cancer Therapeutics·2023· 6 citedOpen Access
Portobelamides A and B and Caciqueamide, Cytotoxic Peptidic Natural Products from a <i>Caldora</i> sp. Marine Cyanobacterium
Journal of Natural Products·2021· 6 cited
Novel Animal Model for Ventricular Ejection Fraction Measured by MRI
Cardiology and Cardiovascular Research·2021Open Access
Correction to “Highly Convergent Total Synthesis and Assignment of Absolute Configuration of Majusculamide D, a Potent and Selective Cytotoxic Metabolite from <i>Moorea</i> sp.”
Organic Letters·2020
Synthesis, Cytotoxicity, and Genotoxicity of 10-Aza-9-oxakalkitoxin, an <i>N</i> , <i>N</i> , <i>O</i> -Trisubstituted Hydroxylamine Analog, or Hydroxalog, of a Marine Natural Product
Journal of the American Chemical Society·2020· 13 cited
A Versatile Chemoenzymatic Synthesis for the Discovery of Potent Cryptophycin Analogs
ACS Chemical Biology·2020· 31 citedOpen Access
Reinvestigation of Mycothiazole Reveals the Penta-2,4-dien-1-ol Residue Imparts Picomolar Potency and 8<i>S</i> Configuration
ACS Medicinal Chemistry Letters·2020· 8 citedOpen Access
The anti-MRSA compound 3-O-alpha-L-(2″,3″-di-p-coumaroyl)rhamnoside (KCR) inhibits protein synthesis in Staphylococcus aureus
Journal of Proteomics·2019· 6 citedOpen Access
Abstract 366: Arctin and arctigenin as a potential treatment for solid tumors
Cancer Research·2019· 1 cited
Abstract 366: Arctin and arctigenin as a potential treatment for solid tumors
Experimental and Molecular Therapeutics·2019
Computationally Assisted Discovery and Assignment of a Highly Strained and PANC-1 Selective Alkaloid from Alaska’s Deep Ocean
Journal of the American Chemical Society·2019· 67 citedOpen Access
Highly Convergent Total Synthesis and Assignment of Absolute Configuration of Majusculamide D, a Potent and Selective Cytotoxic Metabolite from <i>Moorea sp.</i>
Organic Letters·2019· 21 cited
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Frequent Co-authors

Phillip Crews(19), Karen Tenney(13), Thomas H. Corbett(10), Gregory M. L. Patterson(6), Richard E. Moore(6), Tyler A. Johnson(6), William H. Gerwick(6), Susan L. Mooberry(5), Halina Pietraszkiewicz(4), Trimurtulu Golakoti(3), Lisa Demchik(3), Taro Amagata(3), Akiko Amagata(3), Emil B. Lobkovsky(3), Jon Clardy(3), Laurence H. Baker(3), Joseph Media(3), Taro Amagata(3), Lisa Polin(3), Chiab Panchapor(3)