Ribhu Nayar

Q Therapeutics (United States) — United States

Medicine · Health Sciences

9h-index764citations29works0.02yr avg
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Research Topics

CAR-T cell therapy research(15), Immune Cell Function and Interaction(10), T-cell and B-cell Immunology(8), Immunotherapy and Immune Responses(5), Cancer Immunotherapy and Biomarkers(3)

Publications29 total

Dual-inactivation of Regnase-1 and SOCS1 rewires exhausted CD8 <sup>+</sup> T cell fate to enhance anti-tumor functionality
2026Open Access
384 Development of a target agnostic platform to assess the reactivity of T cell receptor (TCR)- engineered T cell (TCR-T) therapies to primary human tissues
Regular and Young Investigator Award Abstracts·2024Open Access
359 Preclinical models for T-Plex, a customized multiplexed TCR-T cell therapy addressing intra-tumor antigen and HLA heterogeneity
Regular and Young Investigator Award Abstracts·2024Open Access
376 Overcoming tumor heterogeneity – Clinical trial assays to prospectively assign patients customized multiplexed TCR-T cell therapy in Phase 1
Regular and Young Investigator Award Abstracts·2023· 1 citedOpen Access
364 Non-clinical development of T-Plex component TSC-200-A0201: a natural HPV16 E7-specific TCR-T cell therapy for the treatment of HPV16-positive solid tumors
Regular and Young Investigator Award Abstracts·2023Open Access
709 Trial in progress: product characteristics and clinical trial design for T-Plex, a multiplexed, enhanced T cell receptor-engineered T cell therapy for solid tumors
Regular and Young Investigator Award Abstracts·2023Open Access
390 Discovery of MAGE-A1-specific TCR-T cell therapy candidates to expand multiplex therapy of solid tumors
Regular and Young Investigator Award Abstracts·2023Open Access
In vivo imaging of bone marrow endothelial dysfunction promoting myeloid cell expansion in cardiovascular disease
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition·2023
Product characteristics and clinical trial design for T-Plex: Multiplexed, enhanced T cell receptor engineered T cell therapy for solid tumors.
Journal of Clinical Oncology·2023
182 Discovery of TSC-203-A02: A PRAME-specific TCR-T cell therapy candidate for the treatment of solid tumors
Regular and Young Investigator Award Abstracts·2022· 1 citedOpen Access
Bone marrow endothelial dysfunction promotes myeloid cell expansion in cardiovascular disease
Nature Cardiovascular Research·2021· 80 citedOpen Access
Discovery of TSC-101: A First-in-Class Natural HA-2-Specific TCR to Treat Leukemia Following Hematopoietic Stem Cell Transplant Therapy
Blood·2021
156 Discovery of TSC-100: A natural HA-1-specific TCR to treat leukemia following hematopoietic stem cell transplant therapy
Regular and Young Investigator Award Abstracts·2020Open Access
Nanoparticle-encapsulated siRNAs for gene silencing in the haematopoietic stem-cell niche
Nature Biomedical Engineering·2020· 119 citedOpen Access
The Transcription Factor Runx2 Is Required for Long-Term Persistence of Antiviral CD8+ Memory T Cells
ImmunoHorizons·2018· 36 citedOpen Access
Imaging the Vascular Bone Marrow Niche During Inflammatory Stress
Circulation Research·2018· 60 citedOpen Access
The role of Runx2 in CD8+ T cell memory during acute LCMV Armstrong infection
The Journal of Immunology·2017· 1 cited
NKG2C/E Marks the Unique Cytotoxic CD4 T Cell Subset, ThCTL, Generated by Influenza Infection
The Journal of Immunology·2016· 66 citedOpen Access
II-13 Suppression of systemic autoimmunity by the innate immune adaptor sting
Innate Immunity·2016Open Access
IRF4 Regulates the Ratio of T-Bet to Eomesodermin in CD8+ T Cells Responding to Persistent LCMV Infection
PLoS ONE·2015· 21 citedOpen Access
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Frequent Co-authors

Leslie J. Berg(12), Antoine Boudot(10), Gavin MacBeath(9), Sonal Jangalwe(8), Nancy Nabilsi(7), Cagan Gurer(7), Livio Dukaj(6), Alexander Cristofaro(6), Daniel C Pollacksmith(6), Qikai Xu(6), Yifan Wang(6), Elizabeth Schutten(5), Michael A. Brehm(5), Raymond M. Welsh(5), Mollie Jurewicz(5), Kimberly M. Cirelli(5), Kenneth L Jahan(5), Victor Ospina(5), Shubhangi Kamalia(5), Jenny Tadros(5)