Yu‐May Lee

Institute of Biological Chemistry, Academia Sinica — Taiwan

Neuroscience · Life Sciences

12h-index696citations25works0.02yr avg
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Research Topics

Genetic Neurodegenerative Diseases(5), Mitochondrial Function and Pathology(4), Metabolism and Genetic Disorders(4), RNA and protein synthesis mechanisms(3), Neurological disorders and treatments(3)

Publications25 total

GPC3 Decreases IGF-1R–Grb10 Interaction and Promotes Cell Invasion in Hepatocellular Carcinoma in a Gender-Dependent Manner
Research Square (Research Square)·2020· 1 citedOpen Access
Gene therapy with modified U1 small nuclear RNA
Expert Review of Endocrinology & Metabolism·2017· 7 cited
Roles of Glypican-3 through IGF axis and Wnt in Hepatocellular Carcinomas
Cancer Research Frontiers·2017
The Novel VEGF<sub>121</sub>-VEGF<sub>165</sub> Fusion Attenuates Angiogenesis and Drug Resistance via Targeting VEGFR2-HIF-1α-VEGF<sub>165</sub>/Lon Signaling Through PI3K-AKT-mTOR Pathway
Current Cancer Drug Targets·2016· 21 cited
Exchange of active site residues alters substrate specificity in extremely thermostable β-glycosidase from Thermococcus kodakarensis KOD1
Enzyme and Microbial Technology·2015· 6 cited
An intermolecular disulfide bond is required for thermostability and thermoactivity of β-glycosidase from Thermococcus kodakarensis KOD1
Applied Microbiology and Biotechnology·2014· 10 cited
Kinetic analysis of β‐Galactosidase activity from <i>Thermococcus kodakarensis</i> KOD1, an extreme thermophile
The FASEB Journal·2012
Inhibition of glutaminyl cyclase attenuates cell migration modulated by monocyte chemoattractant proteins
Biochemical Journal·2011· 23 cited
Glypican-3-mediated oncogenesis involves the Insulin-like growth factor-signaling pathway
Carcinogenesis·2008· 93 citedOpen Access
Overexpression of YTCa, a novel gene can promote growth of NIH3T3 cells
The FASEB Journal·2008
Hsp27 decreases inclusion body formation from mutated GTP-cyclohydrolase I protein
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease·2008· 2 citedOpen Access
Increased oxidative damage and mitochondrial abnormalities in the peripheral blood of Huntington’s disease patients
Biochemical and Biophysical Research Communications·2007· 225 cited
Novel RNA‐binding protein, BEC1 is a splicing factor and interacts with ASF
The FASEB Journal·2007
Molecular chaperones affect GTP cyclohydrolase I mutations in dopa‐responsive dystonia
Annals of Neurology·2004· 10 cited
Differential Activation of a C/EBPβ Isoform by a Novel Redox Switch May Confer the Lipopolysaccharide-inducible Expression of Interleukin-6 Gene
Journal of Biological Chemistry·2003· 30 citedOpen Access
Regulation of GTP cyclohydrolase I by alternative splicing in mononuclear cells
Biochemical and Biophysical Research Communications·2003· 14 cited
Cloning and Characterization of a Complementary DNA Encoding a Human Epididymis-Associated Disintegrin and Metalloprotease 7 Protein1
Biology of Reproduction·2001· 23 citedOpen Access
Cloning of Dimethylglycine Dehydrogenase and a New Human Inborn Error of Metabolism, Dimethylglycine Dehydrogenase Deficiency
The American Journal of Human Genetics·2001· 70 citedOpen Access
Dopa-responsive dystonia is induced by a dominant-negative mechanism
Annals of Neurology·2000· 36 cited
Dopa‐responsive dystonia is induced by a dominant‐negative mechanism
Annals of Neurology·2000· 1 cited
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Frequent Co-authors

Wuh‐Liang Hwu(10), Sheng-Chung Lee(5), Kuo‐Yuan Hwa(5), Yu‐Wei Chiou(4), Boopathi Subramani(3), San-Tai Shen(3), Chia‐Jen Tseng(2), Ching‐Jin Chang(2), Su‐Yi Lai(2), Wen-Hai Tsai(2), Ming–Yang Lai(2), Ding‐Shinn Chen(2), Shu-Hsiang Liu(2), Wei Cheng(2), Chiung‐Mei Chen(1), Yih‐Ru Wu(1), Mei‐Ling Cheng(1), Junliang Liu(1), Po-Wei Lee(1), Bing‐Wen Soong(1)