Frédéric J. de Sauvage

Genentech

Biochemistry, Genetics and Molecular Biology · Life Sciences

103h-index48.4kcitations301works0.02yr avg
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Research Topics

Hedgehog Signaling Pathway Studies(117), Epigenetics and DNA Methylation(38), Cancer and Skin Lesions(28), Nonmelanoma Skin Cancer Studies(25), Cancer Cells and Metastasis(24)

Publications300 total

Tumor-intrinsic expression of the autophagy gene Atg16l1 suppresses anti-tumor immunity in colorectal cancer
Nature Communications·2023· 33 citedOpen Access
Adrenergic nerves regulate intestinal regeneration through IL-22 signaling from type 3 innate lymphoid cells
Cell stem cell·2023· 38 citedOpen Access
Abstract A039: RAS signaling strength determines phenotypic response in the colon
Molecular Cancer Research·2023
Supplementary Data from Frequency and Genomic Aspects of Intrinsic Resistance to Vismodegib in Locally Advanced Basal Cell Carcinoma
2023Open Access
Supplementary Figure from Frequency and Genomic Aspects of Intrinsic Resistance to Vismodegib in Locally Advanced Basal Cell Carcinoma
2023Open Access
Supplementary Data Figures from A Clinically Applicable Gene-Expression Classifier Reveals Intrinsic and Extrinsic Contributions to Consensus Molecular Subtypes in Primary and Metastatic Colon Cancer
2023Open Access
Supplementary Figure from Frequency and Genomic Aspects of Intrinsic Resistance to Vismodegib in Locally Advanced Basal Cell Carcinoma
2023Open Access
Supplementary Data Figures from A Clinically Applicable Gene-Expression Classifier Reveals Intrinsic and Extrinsic Contributions to Consensus Molecular Subtypes in Primary and Metastatic Colon Cancer
2023Open Access
Supplementary Data Tables from A Clinically Applicable Gene-Expression Classifier Reveals Intrinsic and Extrinsic Contributions to Consensus Molecular Subtypes in Primary and Metastatic Colon Cancer
2023Open Access
Supplementary Figure 1 from Pharmacokinetic–Pharmacodynamic Analysis of Vismodegib in Preclinical Models of Mutational and Ligand-Dependent Hedgehog Pathway Activation
2023Open Access
Data from Pharmacokinetic–Pharmacodynamic Analysis of Vismodegib in Preclinical Models of Mutational and Ligand-Dependent Hedgehog Pathway Activation
2023Open Access
Data from Pharmacokinetic–Pharmacodynamic Analysis of Vismodegib in Preclinical Models of Mutational and Ligand-Dependent Hedgehog Pathway Activation
2023Open Access
Supplementary Figure from Frequency and Genomic Aspects of Intrinsic Resistance to Vismodegib in Locally Advanced Basal Cell Carcinoma
2023Open Access
Supplementary Figure from Frequency and Genomic Aspects of Intrinsic Resistance to Vismodegib in Locally Advanced Basal Cell Carcinoma
2023Open Access
Supplementary Figure from Frequency and Genomic Aspects of Intrinsic Resistance to Vismodegib in Locally Advanced Basal Cell Carcinoma
2023Open Access
Supplementary Figure from Frequency and Genomic Aspects of Intrinsic Resistance to Vismodegib in Locally Advanced Basal Cell Carcinoma
2023Open Access
Data from Frequency and Genomic Aspects of Intrinsic Resistance to Vismodegib in Locally Advanced Basal Cell Carcinoma
2023Open Access
Supplementary Data Tables from A Clinically Applicable Gene-Expression Classifier Reveals Intrinsic and Extrinsic Contributions to Consensus Molecular Subtypes in Primary and Metastatic Colon Cancer
2023Open Access
Supplementary Figure from Frequency and Genomic Aspects of Intrinsic Resistance to Vismodegib in Locally Advanced Basal Cell Carcinoma
2023Open Access
Supplementary Figure from Frequency and Genomic Aspects of Intrinsic Resistance to Vismodegib in Locally Advanced Basal Cell Carcinoma
2023Open Access
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Frequent Co-authors

Zora Modrušan(15), Jeremy Stinson(11), Somasekar Seshagiri(11), Robert L. Yauch(8), Peter M. Haverty(8), Subhra Chaudhuri(7), Bijay S. Jaiswal(7), Howard M. Stern(7), Nico Ghilardi(6), Steffen Durinck(6), Eric Stawiski(6), Vasantharajan Janakiraman(6), Zemin Zhang(6), Thomas D. Wu(6), Richard Bourgon(6), Arnon Rosenthal(5), Charles M. Rudin(5), Joseph Guillory(5), Robert Gentleman(5), Stephen E. Gould(5)