Janne T. Backman

University of Helsinki — Finland

Pharmacology, Toxicology and Pharmaceutics · Life Sciences

70h-index16.1kcitations269works3.02yr avg
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Research Topics

Pharmacogenetics and Drug Metabolism(117), Drug Transport and Resistance Mechanisms(81), Pharmacological Effects and Toxicity Studies(51), Inflammatory mediators and NSAID effects(25), Antiplatelet Therapy and Cardiovascular Diseases(23)

Publications269 total

Early-career pre-congress meetings: investing in talent, transforming the future of clinical pharmacology
European Journal of Clinical Pharmacology·2025
Repeated Intake of Grapefruit Juice Inhibits <scp>CYP2B6</scp> , <scp>CYP2C9</scp> , <scp>CYP2C19</scp> , and <scp>CYP3A4</scp> while Lingonberry Powder Does Not Induce Major <scp>CYP</scp> Enzymes in Humans
Clinical Pharmacology & Therapeutics·2025Open Access
Clinical pharmacology consultations and their implementation in clinical decision making
British Journal of Clinical Pharmacology·2025Open Access
Toward a More accurate, Evidence‐Based Classification of <scp>CYP</scp> Inhibitors: A Critical Appraisal of Current Systems
Clinical Pharmacology & Therapeutics·2025Open Access
Challenging the young and shaping the growth of clinical pharmacology: 10 years of the EACPT Early Career Clinical Pharmacologists (ECCP) working group
European Journal of Clinical Pharmacology·2025· 1 cited
A seven cytochrome P450 index substrate cocktail for clinical trials – Profiling the effects of clopidogrel and gemfibrozil on CYP enzymes and OATP1B1 biomarkers
Drug Metabolism and Pharmacokinetics·2025
Capillary Sampling Enables Venetoclax Concentration Measurement in Acute Myeloid Leukaemia Within Academic Multicentre Trial
Basic & Clinical Pharmacology & Toxicology·2025· 1 citedOpen Access
Identification of Genetic Variants Associated with Pravastatin and Pitavastatin Pharmacokinetics
Clinical Pharmacology & Therapeutics·2025· 3 citedOpen Access
A Phenotyping Tool for Seven Cytochrome P450 Enzymes and Two Transporters: Application to Examine the Effects of Clopidogrel and Gemfibrozil
Clinical Pharmacology & Therapeutics·2025· 2 citedOpen Access
Misfolding of transthyretin in vivo is controlled by the redox environment and macromolecular crowding
Journal of Biological Chemistry·2024· 8 citedOpen Access
Candesartan Has No Clinically Meaningful Effect on the Plasma Concentrations of Cytochrome P450 2C8 Substrate Repaglinide in Humans
Drug Metabolism and Disposition·2024· 3 citedOpen Access
Population Pharmacokinetic Quantification of CYP2D6 Activity in Codeine Metabolism in Ambulatory Surgical Patients for Model-Informed Precision Dosing
Clinical Pharmacokinetics·2024· 4 citedOpen Access
In vitro assessment of inhibitory effects of kinase inhibitors on CYP2C9, 3A and 1A2: Prediction of drug-drug interaction risk with warfarin and direct oral anticoagulants
European Journal of Pharmaceutical Sciences·2024· 6 citedOpen Access
Elucidating the Drug-Drug Interaction Potential of Hydroxychloroquine Metabolites due to Direct and Time-Dependent Inhibition of CYP3A
Journal of Pharmacology and Experimental Therapeutics·2024
Genome‐Wide Association Study of Atorvastatin Pharmacokinetics: Associations With <i>SLCO1B1</i>, <i>UGT1A3</i>, and <i>LPP</i>
Clinical Pharmacology & Therapeutics·2024· 10 citedOpen Access
The effect of hydroxychloroquine on cholesterol synthesis depends on the profile of cholesterol metabolism. A controlled clinical study
Atherosclerosis Plus·2024· 3 citedOpen Access
Non‐targeted metabolomics for the identification of plasma metabolites associated with organic anion transporting polypeptide <scp>1B1</scp> function
Clinical and Translational Science·2024· 5 citedOpen Access
Screening of 16 major drug glucuronides for time-dependent inhibition of nine drug-metabolizing CYP enzymes – detailed studies on CYP3A inhibitors
European Journal of Pharmaceutical Sciences·2024· 8 citedOpen Access
Posaconazole‐ibrutinib interaction cannot be avoided by staggered dosing: How to optimize ibrutinib dose during posaconazole treatment
British Journal of Clinical Pharmacology·2023· 3 citedOpen Access
Drug‐related deaths in a university hospital: Comparison to previous decades
Basic & Clinical Pharmacology & Toxicology·2023· 1 citedOpen Access
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Frequent Co-authors

Pertti J. Neuvonen(40), Mikko Niemi(19), Mikko Neuvonen(13), Kari T. Kivistö(11), Jouko Laitila(9), Klaus T. Olkkola(6), Aleksi Tornio(5), Wen Xia(5), Michel Eichelbaum(4), Lauri Kajosaari(4), Junsheng Wang(4), Marika T. Granfors(4), Anne M. Filppula(3), Martin F. Fromm(2), Thomas Lang(2), Carl Kyrklund(2), Matthias Schwab(2), Harri Luurila(2), Tiina Jaakkola(2), Jari J. Lilja(2)