Brian Golbourn

University of Pittsburgh — United States

Medicine · Health Sciences

20h-index1.5kcitations175works2.02yr avg
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Research Topics

Glioma Diagnosis and Treatment(88), Microtubule and mitosis dynamics(29), Chromatin Remodeling and Cancer(27), Hedgehog Signaling Pathway Studies(25), Cancer, Hypoxia, and Metabolism(22)

Publications167 total

A kinome drug screen identifies multi-TKI synergies and ERBB2 signaling as a therapeutic vulnerability in MYC/TYR subgroup atypical teratoid rhabdoid tumors
Neuro-Oncology·2024· 2 citedOpen Access
An ERK5-PFKFB3 axis regulates glycolysis and represents a therapeutic vulnerability in pediatric diffuse midline glioma
Cell Reports·2023· 15 citedOpen Access
DIPG-36. H3K27M HISTONE MUTANT GLIOMAS ARE SENSITIVE TO METHIONINE LOSS AND MAT2A INHIBITION THROUGH A NOVEL FEEDBACK MECHANISM BETWEEN AMD1 AND METTL16
Neuro-Oncology·2023Open Access
Targeting mitochondrial energetics reverses panobinostat‐ and marizomib‐induced resistance in pediatric and adult high‐grade gliomas
Molecular Oncology·2023· 9 citedOpen Access
Supplemental Figure Legends from ATM Regulates 3-Methylpurine-DNA Glycosylase and Promotes Therapeutic Resistance to Alkylating Agents
2023Open Access
Supplemental Figures 1 - 9 from ATM Regulates 3-Methylpurine-DNA Glycosylase and Promotes Therapeutic Resistance to Alkylating Agents
2023Open Access
Table S1 from ZFTA–RELA Dictates Oncogenic Transcriptional Programs to Drive Aggressive Supratentorial Ependymoma
2023Open Access
Supplementary File 3 from Targeting NAD<sup>+</sup> Biosynthesis Overcomes Panobinostat and Bortezomib-Induced Malignant Glioma Resistance
2023Open Access
Supplementary Figure 5 from Targeting NAD<sup>+</sup> Biosynthesis Overcomes Panobinostat and Bortezomib-Induced Malignant Glioma Resistance
2023Open Access
Table S6 from ZFTA–RELA Dictates Oncogenic Transcriptional Programs to Drive Aggressive Supratentorial Ependymoma
2023Open Access
Supplemental Methods from ATM Regulates 3-Methylpurine-DNA Glycosylase and Promotes Therapeutic Resistance to Alkylating Agents
2023Open Access
Supplementary Figure 4 from Targeting NAD<sup>+</sup> Biosynthesis Overcomes Panobinostat and Bortezomib-Induced Malignant Glioma Resistance
2023Open Access
Table S6 from ZFTA–RELA Dictates Oncogenic Transcriptional Programs to Drive Aggressive Supratentorial Ependymoma
2023Open Access
Figure S3 from ZFTA–RELA Dictates Oncogenic Transcriptional Programs to Drive Aggressive Supratentorial Ependymoma
2023Open Access
Figure S5 from ZFTA–RELA Dictates Oncogenic Transcriptional Programs to Drive Aggressive Supratentorial Ependymoma
2023Open Access
Supplementary Figure 1 - PARP1 protein is expressed in pHGA and DIPG patient samples from Poly-ADP-Ribose Polymerase as a Therapeutic Target in Pediatric Diffuse Intrinsic Pontine Glioma and Pediatric High-Grade Astrocytoma
2023Open Access
Supplementary Figure 4 - Niraparib induces growth arrest in SJG2 and SF188 cells. from Poly-ADP-Ribose Polymerase as a Therapeutic Target in Pediatric Diffuse Intrinsic Pontine Glioma and Pediatric High-Grade Astrocytoma
2023Open Access
Supplemental Methods from ATM Regulates 3-Methylpurine-DNA Glycosylase and Promotes Therapeutic Resistance to Alkylating Agents
2023Open Access
Supplementary File 2 from Targeting NAD<sup>+</sup> Biosynthesis Overcomes Panobinostat and Bortezomib-Induced Malignant Glioma Resistance
2023Open Access
Figure S6 from ZFTA–RELA Dictates Oncogenic Transcriptional Programs to Drive Aggressive Supratentorial Ependymoma
2023Open Access
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Frequent Co-authors

James T. Rutka(34), Sameer Agnihotri(30), Christian A. Smith(24), Michael D. Taylor(16), Stephen C. Mack(16), Marc Remke(15), N. Sabha(15), Amanda Luck(12), Cynthia Hawkins(12), Kelsey C. Bertrand(12), Vijay Ramaswamy(9), Cláudia C. Faria(9), Gelareh Zadeh(9), Esther P. Jane(8), Daniel R. Premkumar(8), Nada Jabado(8), Ian F. Pollack(8), Stefan M. Pfister(8), Peter B. Dirks(8), Roberto J. Diaz(8)