Ruowen Ge

National University of Singapore — Singapore

Biochemistry, Genetics and Molecular Biology · Life Sciences

39h-index4.8kcitations108works2.02yr avg
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Research Topics

Angiogenesis and VEGF in Cancer(28), Cell Adhesion Molecules Research(17), Virus-based gene therapy research(11), Protease and Inhibitor Mechanisms(9), Zebrafish Biomedical Research Applications(9)

Publications108 total

Ism1 deficiency in mice exacerbates bleomycin-induced pulmonary fibrosis with enhanced cellular senescence and delayed fibrosis resolution
hLife·2024· 2 citedOpen Access
Isthmin-1 attenuates allergic Asthma by stimulating adiponectin expression and alveolar macrophage efferocytosis in mice
Respiratory Research·2023· 12 citedOpen Access
Unveiling the role of Isthmin-1 in allergic asthma: Implications for therapeutic interventions
2023· 1 cited
Bistable insulin response: The win-win solution for glycemic control
iScience·2022· 12 citedOpen Access
Targeting airway macrophages for inflammatory lung diseases—insights from traditional Chinese medicine
Annals of Translational Medicine·2022· 4 citedOpen Access
Lipid Nanoparticles as Delivery Vehicles for Inhaled Therapeutics
Biomedicines·2022· 103 citedOpen Access
ISM1 suppresses LPS-induced acute lung injury and post-injury lung fibrosis in mice
Molecular Medicine·2022· 73 citedOpen Access
Cell surface nucleolin is a novel ADAMTS5 receptor mediating endothelial cell apoptosis
Cell Death and Disease·2022· 18 citedOpen Access
Developing inhaled protein therapeutics for lung diseases
Molecular Biomedicine·2020· 69 citedOpen Access
Discovery of small molecules targeting GRP78 for antiangiogenic and anticancer therapy
European Journal of Medicinal Chemistry·2020· 18 cited
Cell Surface GRP78 as a Death Receptor and an Anticancer Drug Target
Cancers·2019· 51 citedOpen Access
Proapoptotic Cyclic Peptide BC71 Targets Cell-Surface GRP78 and Functions as an Anticancer Therapeutic in Mice
EBioMedicine·2018· 38 citedOpen Access
Recombinant TSR1 of ADAMTS5 Suppresses Melanoma Growth in Mice via an Anti-angiogenic Mechanism
Cancers·2018· 13 citedOpen Access
Angio-3, a 10-residue peptide derived from human plasminogen kringle 3, suppresses tumor growth in mice via impeding both angiogenesis and vascular permeability
Angiogenesis·2018· 26 cited
Extracellular vesicle-carried Jagged-1 inhibits HUVEC sprouting in a 3D microenvironment
Angiogenesis·2018· 22 cited
Extracellular anti-angiogenic proteins augment an endosomal protein trafficking pathway to reach mitochondria and execute apoptosis in HUVECs
Cell Death and Differentiation·2018· 35 citedOpen Access
Efficient genome editing using CRISPR/Cas9 ribonucleoprotein approach in cultured medaka fish cells
Biology Open·2018· 33 citedOpen Access
An Electromagnetic System for Inducing a Localized Force Gradient in an ECM and Its Influence on HMVEC Sprouting
SLAS TECHNOLOGY·2017· 3 citedOpen Access
A Magneto-Microfluidic System for Investigating the Influence of an Externally Induced Force Gradient in a Collagen Type I ECM on HMVEC Sprouting
SLAS TECHNOLOGY·2016· 10 citedOpen Access
Loss of ADAMTS4 reduces high fat diet-induced atherosclerosis and enhances plaque stability in ApoE−/− mice
Scientific Reports·2016· 56 citedOpen Access
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Frequent Co-authors

Husnain Kh Haider(8), Lei Ye(7), Eugene K.W. Sim(7), R. Manjunatha Kini(5), Soheila Sharghi-Namini(4), K.N. Sulochana(4), Yong Zhang(4), Saran Kumar(4), Nithya Rao(4), Peter K. Law(4), Shujia Jiang(4), Robert P. Ricciardi(4), Muhammad Farooq(3), Yap Seng Chong(3), Ru‐San Tan(3), Wei Xiang(3), Kian Keong Poh(3), Yi Zhun Zhu(3), Yunhan Hong(3), Mark Bartlam(2)