Gene P. Siegal

University of Alabama at Birmingham — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

63h-index17.3kcitations464works1.72yr avg
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Research Topics

Virus-based gene therapy research(99), Sarcoma Diagnosis and Treatment(81), Bone Tumor Diagnosis and Treatments(62), CAR-T cell therapy research(38), Oral and Maxillofacial Pathology(35)

Publications462 total

Association between p16INK4A expression and a treatment response to CDK4/6 inhibitor in advanced breast carcinoma
Human Pathology·2025
A Genomic Alteration in GATA3 Affects Treatment Responses With a CDK4/6 Inhibitor Collaborating With p18INK4C Expression in Advanced Breast Carcinoma
Modern Pathology·2025· 1 cited
Predictive biomarkers for immune checkpoint inhibitor (ICI) and poly (ADP-ribose) polymerase (PARP) inhibitor (PARPi) in advanced-stage breast carcinoma
Human Pathology Reports·2025Open Access
112 A Truncating Mutation of the GATA3 Gene Affects the Treatment Response with a CDK4/6 Inhibitor via p18/INK4C Expression in Advanced Breast Carcinoma
Laboratory Investigation·2025Open Access
111 Association between p16/INK4A Expression and a Treatment Response with a CDK4/6 Inhibitor in Advanced Breast Carcinoma
Laboratory Investigation·2025Open Access
Reduced GATA3 expression during breast cancer progression: A potential anchor for pulmonary metastatic deposition
Pathology - Research and Practice·2025
Soft tissue hemangioma of the right upper extremity with intraosseous extension and secondary intravascular papillary endothelial hyperplasia
Skeletal Radiology·2024Open Access
p53 protein expression patterns associated with TP53 mutations in breast carcinoma
Breast Cancer Research and Treatment·2024· 10 citedOpen Access
Comparison of PD-L1 (22C3) Expression in Paired Primary and Metastatic Breast Carcinoma
Clinical Breast Cancer·2024· 7 cited
Continuous Low-Intensity Ultrasound Improves Cartilage Repair in Rabbit Model of Subchondral Injury
Tissue Engineering Part A·2024· 1 citedOpen Access
Palmar Nodular Fasciitis Harboring a Novel <i>SREBF1::USP6</i> Fusion Gene
International Journal of Surgical Pathology·2024
The Peritumoral CD8+/FOXP3+ Cell Ratio Has Prognostic Value in Triple-negative Breast Cancer
Applied immunohistochemistry & molecular morphology·2023· 4 cited
The dynamics of HER2-low expression during breast cancer progression
Breast Cancer Research and Treatment·2023· 19 cited
An Aneurysmal bone cyst harboring a novel ACSL4::USP6 fusion gene
Journal of Orthopaedic Science·2023· 1 cited
Mutations in Homologous Recombination Genes and Loss of Heterozygosity Status in Advanced-Stage Breast Carcinoma
Cancers·2023· 3 citedOpen Access
Data from Alpha-CaMKII Plays a Critical Role in Determining the Aggressive Behavior of Human Osteosarcoma
2023Open Access
Data from Alpha-CaMKII Plays a Critical Role in Determining the Aggressive Behavior of Human Osteosarcoma
2023Open Access
Supplementary Figure 1 from A Phase I Clinical Trial of Ad5.SSTR/TK.RGD, a Novel Infectivity-Enhanced Bicistronic Adenovirus, in Patients with Recurrent Gynecologic Cancer
2023Open Access
Data from Silencing of Transforming Growth Factor-β1 &lt;i&gt;In situ&lt;/i&gt; by RNA Interference for Breast Cancer: Implications for Proliferation and Migration &lt;i&gt;In vitro&lt;/i&gt; and Metastasis &lt;i&gt;In vivo&lt;/i&gt;
2023Open Access
Supplementary Figure 1 from A Phase I Clinical Trial of Ad5.SSTR/TK.RGD, a Novel Infectivity-Enhanced Bicistronic Adenovirus, in Patients with Recurrent Gynecologic Cancer
2023Open Access
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Frequent Co-authors

David T. Curiel(14), Minghui Wang(10), Ronald D. Alvarez(7), Mark L. Bernstein(4), William S. Ferguson(4), Allen M. Goorin(4), Holcombe E. Grier(4), Mack N. Barnes(4), Akseli Hemminki(4), Paul A. Meyers(3), Cindy L. Schwartz(3), Mark Krailo(3), Mark C. Gebhardt(3), Michael B. Harris(3), Michael P. Link(3), Ángel A. Rivera(3), Anna Kanerva(3), Buck E. Rogers(3), Walter C. Bell(3), Bin Liu(3)