Tamene Melkamu

Recombinetics (United States) — United States

Immunology and Microbiology · Life Sciences

13h-index723citations26works0.02yr avg
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Research Topics

Immune Response and Inflammation(5), Asthma and respiratory diseases(3), MicroRNA in disease regulation(3), Cancer-related molecular mechanisms research(3), Genomics, phytochemicals, and oxidative stress(3)

Publications26 total

Author Correction: Dysregulated ribonucleoprotein granules promote cardiomyopathy in RBM20 gene-edited pigs
Nature Medicine·2021
Sa119 RECRUITMENT OF POLARITY COMPLEXES AND TIGHT JUNCTION PROTEINS TO THE SITE OF APICAL BULK ENDOCYTOSIS
Gastroenterology·2021
Recruitment of Polarity Complexes and Tight Junction Proteins to the Site of Apical Bulk Endocytosis
Cellular and Molecular Gastroenterology and Hepatology·2021· 13 citedOpen Access
Dysregulated ribonucleoprotein granules promote cardiomyopathy in RBM20 gene-edited pigs
Nature Medicine·2020· 118 citedOpen Access
118 GENE EDITNG OF SWINE MYOSIN VB RESULTS IN MICROVILLUS INCLUSION DISEASE AND DEFICITS IN APICAL TRANSPORTERS IN THE INTESTINE AND ALTERATIONS IN LIVER CANALICULAR PROTEINS
Gastroenterology·2020
A PNPLA3 <sup>I148M</sup> gene‐edited Ossabaw swine model of Nonalcoholic steatohepatitis (NASH)
The FASEB Journal·2020· 1 cited
Editing Myosin VB Gene to Create Porcine Model of Microvillus Inclusion Disease, With Microvillus-Lined Inclusions and Alterations in Sodium Transporters
Gastroenterology·2020· 37 citedOpen Access
240 – Role of Myosin Vb in Trafficking of Apical Membrane Proteins in Hepatocytes
Gastroenterology·2019· 1 cited
Gene Editing of Swine Myosin Vb Induces Microvillus Inclusion Disease and Loss of Apical Sodium Transporters with Maintenance of CFTR in Enterocytes
The FASEB Journal·2019· 1 cited
1083 - Gene Editing of the Navajo P660L Mutation Into Swine Myosin Vb Induces Microvillus Inclusion Disease and Loss of Apical Enterocyte Transporters
Gastroenterology·2018
Ossabaw Pigs With a PCSK9 Gain‐of‐Function Mutation Develop Accelerated Coronary Atherosclerotic Lesions: A Novel Model for Preclinical Studies
Journal of the American Heart Association·2018· 28 citedOpen Access
ATP release and Ca<sup>2+</sup> signalling by human bronchial epithelial cells following <i>Alternaria</i> aeroallergen exposure
The Journal of Physiology·2013· 38 citedOpen Access
Lipopolysaccharide Enhances Mouse Lung Tumorigenesis
Veterinary Pathology·2013· 68 citedOpen Access
Chemoprevention of lung tumorigenesis by intranasally administered diindolylmethane in A/J mice
Carcinogenesis·2012· 10 citedOpen Access
TLR3 activation evokes IL-6 secretion, autocrine regulation of Stat3 signaling and TLR2 expression in human bronchial epithelial cells
Journal of Cell Communication and Signaling·2012· 33 citedOpen Access
Abstract B41: A mouse model for inflammation-driven lung tumorigenesis
Cancer Prevention Research·2011· 2 cited
Indole-3-carbinol inhibited tobacco smoke carcinogen-induced lung adenocarcinoma in A/J mice when administered during the post-initiation or progression phase of lung tumorigenesis
Cancer Letters·2011· 46 cited
Abstract 160: Altered levels of circulating microRNAs in the plasma of non-small cell lung cancer patients: Potential as biomarker
Cancer Research·2011· 3 cited
Enhanced inhibition of lung adenocarcinoma by combinatorial treatment with indole-3-carbinol and silibinin in A/J mice
Carcinogenesis·2011· 45 citedOpen Access
Inhibition of lung carcinogenesis and critical cancer-related signaling pathways by N-acetyl-S-(N-2-phenethylthiocarbamoyl)-l-cysteine, indole-3-carbinol and myo-inositol, alone and in combination
Carcinogenesis·2010· 54 citedOpen Access
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Frequent Co-authors

Fekadu Kassie(10), Daniel F. Carlson(10), Amy C. Engevik(7), Milena Saqui–Salces(7), James R. Goldenring(7), Alexander Coutts(6), Pramod Upadhyaya(6), Izumi Kaji(6), Scott M. O’Grady(4), Anne R. Meyer(4), Alex Coutts(4), Dennis A. Webster(3), Scott C. Fahrenkrug(3), Xing‐Kai Qian(3), Xuemin Qian(3), Hirohito Kita(3), Ramya Lekha Medida(3), Janice A. Williams(3), Jay W. Schneider(2), Saji Oommen(2)