Patrick G. Holt

The Kids Research Institute Australia — Australia

Medicine · Health Sciences

108h-index45.1kcitations752works0.82yr avg
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Research Topics

Asthma and respiratory diseases(302), Immune Cell Function and Interaction(157), Allergic Rhinitis and Sensitization(105), IL-33, ST2, and ILC Pathways(100), Pediatric health and respiratory diseases(100)

Publications742 total

Atopy-related immune profiles are subject to genetic influence as evaluated using school-aged twin pairs
Science Advances·2025Open Access
Immune impacts of infant whole-cell and acellular pertussis vaccination on co-administered vaccines
Journal of Infection·2025Open Access
Immunogenicity of co-administered vaccine antigens with whole-cell or acellular pertussis vaccines in infancy: a randomised controlled trial
2025Open Access
Association of Host CDHR3 rs6967330 Genotype with Rhinovirus Infections in Children from 1997-2018
Journal of Allergy and Clinical Immunology·2025Open Access
Infants hospitalised for severe viral bronchiolitis manifest dysregulated interferon (particularly types 1 & 3) responses
Figshare·2024Open Access
Immunogenicity, reactogenicity, and IgE-mediated immune responses of a mixed whole-cell and acellular pertussis vaccine schedule in Australian infants: A randomised, double-blind, noninferiority trial
PLoS Medicine·2024· 4 citedOpen Access
Mapping Lung Hematopoietic Progenitors: Developmental Kinetics and Response to Influenza A Infection
American Journal of Respiratory Cell and Molecular Biology·2024· 2 cited
Rhinovirus circulation patterns and age predilection of infection in children from 1997-2018
Journal of Allergy and Clinical Immunology·2024Open Access
Immunogenicity, reactogenicity, and IgE-mediated immune responses of a mixed whole-cell and acellular pertussis vaccine schedule in Australian infants: a randomised, double-blind, non-inferiority trial
2023Open Access
Impaired interferon response in plasmacytoid dendritic cells from children with persistent wheeze
Journal of Allergy and Clinical Immunology·2023· 10 citedOpen Access
Single cell transcriptomics reveals cell type specific features of developmentally regulated responses to lipopolysaccharide between birth and 5 years
Frontiers in Immunology·2023· 5 citedOpen Access
Mapping lung hematopoietic progenitors: Developmental kinetics and response to Influenza A viral infection
2023Open Access
Rhinoviruses A and C elicit long‐lasting antibody responses with limited cross‐neutralization
Journal of Medical Virology·2023· 14 citedOpen Access
LPS binding protein and activation signatures are upregulated during asthma exacerbations in children
Respiratory Research·2023· 9 citedOpen Access
Single cell transcriptomics reveals cell type specific features of developmentally regulated responses to lipopolysaccharide between birth and 5 years
2023
Maternal diet modulates the infant microbiome and intestinal Flt3L necessary for dendritic cell development and immunity to respiratory infection
Immunity·2023· 53 citedOpen Access
The maternal microbiome regulates infant respiratory disease susceptibility via intestinal Flt3L expression and plasmacytoid dendritic cell hematopoiesis
2023· 2 citedOpen Access
Additional file 10 of LPS binding protein and activation signatures are upregulated during asthma exacerbations in children
UWA Profiles and Research Repository (UWA)·2023Open Access
Lipopolysaccharide-induced interferon response networks at birth are predictive of severe viral lower respiratory infections in the first year of life
Frontiers in Immunology·2022· 26 citedOpen Access
Asthma and allergies in a cohort of adolescents conceived with ART
Reproductive BioMedicine Online·2022· 9 cited
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Frequent Co-authors

Peter D. Sly(25), Barbara J. Holt(7), Susan L. Prescott(6), Adnan Ćustović(5), Nicholas de Klerk(5), Anthony James(5), Merci Kusel(4), Claudia Macaubas(4), Manuel A. R. Ferreira(4), Raquel Granell(4), Jennie Hui(4), Philip A. Stumbles(4), Guy Brusselle(3), Fernando D. Martínez(3), Andrew Bush(3), Michael Serralha(3), Sebastian L. Johnston(3), Hans Bisgaard(3), Klaus Bønnelykke(3), Alexessander Couto Alves(3)