Lieneke Kooijman

Royal Netherlands Academy of Arts and Sciences — Netherlands

Medicine · Health Sciences

19h-index2.8kcitations32works8.52yr avg
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Research Topics

Alzheimer's disease research and treatments(11), Congenital heart defects research(8), Cardiac Fibrosis and Remodeling(7), Neuroinflammation and Neurodegeneration Mechanisms(6), Tissue Engineering and Regenerative Medicine(5)

Publications32 total

Cross-species comparison reveals that Hmga1 reduces H3K27me3 levels to promote cardiomyocyte proliferation and cardiac regeneration
Nature Cardiovascular Research·2025· 10 citedOpen Access
Hypoxia-responsive zinc finger E-box-binding homeobox 2 (ZEB2) regulates a network of calcium-handling genes in the injured heart
Cardiovascular Research·2024· 7 citedOpen Access
Hydrogel‐Based Delivery of antimiR‐195 Improves Cardiac Efficacy after Ischemic Injury
Advanced Therapeutics·2023· 5 citedOpen Access
Thymosin β4 and prothymosin α promote cardiac regeneration post-ischaemic injury in mice
Cardiovascular Research·2022· 18 citedOpen Access
Cover Image, Volume 70, Issue 4
Glia·2022Open Access
No persistent effects of intracerebral curcumin administration on seizure progression and neuropathology in the kindling rat model for temporal lobe epilepsy
Epilepsy Research·2022· 6 citedOpen Access
Amyloid‐β plaques affect astrocyte Kir4.1 protein expression but not function in the dentate gyrus of <scp>APP</scp>/<scp>PS1</scp> mice
Glia·2022· 19 citedOpen Access
Single-cell transcriptomics following ischemic injury identifies a role for B2M in cardiac repair
Communications Biology·2021· 68 citedOpen Access
Cardiomyocytes stimulate angiogenesis after ischemic injury in a ZEB2-dependent manner
Nature Communications·2021· 112 citedOpen Access
ZEB2 regulates a transcriptional network of calcium-handling genes in the injured heart
European Heart Journal·2020· 1 citedOpen Access
Gene expression profiling of hypertrophic cardiomyocytes identifies new players in pathological remodelling
Cardiovascular Research·2020· 85 citedOpen Access
Hypoxia-dependent Zeb2 transcription factor regulates cardiac repair after ischemic injury
Journal of Molecular and Cellular Cardiology·2020
Abstract 369: Epigenetic Regulation of Cardiomyocyte Proliferation and Regeneration by Swi/snf Complex Subunit Arid1a
Circulation Research·2019
Curcumin reduces development of seizurelike events in the hippocampal‐entorhinal cortex slice culture model for epileptogenesis
Epilepsia·2019· 22 citedOpen Access
Profiling proliferative cells and their progeny in damaged murine hearts
Proceedings of the National Academy of Sciences·2018· 172 citedOpen Access
Abstract 16614: Single-Cell RNA Sequencing Reveals ZEB2 as a Cardioprotective Factor After Ischemic Injury
Circulation·2018
Effects of rapamycin and curcumin on inflammation and oxidative stress in vitro and in vivo — in search of potential anti-epileptogenic strategies for temporal lobe epilepsy
Journal of Neuroinflammation·2018· 76 citedOpen Access
Zeb2 protects the heart from ischemic damage by enhancing the release of cardioprotective factors
Journal of Molecular and Cellular Cardiology·2018
P96Supramolecular hydrogel for local cardiac delivery of antimiR therapeutics
Cardiovascular Research·2018· 1 citedOpen Access
Postnatal Cardiac Gene Editing Using CRISPR/Cas9 With AAV9-Mediated Delivery of Short Guide RNAs Results in Mosaic Gene Disruption
Circulation Research·2017· 66 citedOpen Access
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Frequent Co-authors

Daniëlle Versteeg(15), Eva van Rooij(15), Elly M. Hol(13), Willem Kamphuis(9), Monika M Gladka(9), Bas Molenaar(9), Marie Orre(7), Arwa Kohela(6), Mauro Giacca(6), Lana M. Osborn(4), Jacqueline A. Sluijs(4), Cato M. Drion(4), Erwin A. van Vliet(4), Jan A. Gorter(4), Anne H. P. Jansen(3), Manon M. H. Huibers(3), Danny Huylebroeck(3), Marta Vigil‐Garcia(3), Charlotte J. Demkes(3), Hesther de Ruiter(3)