Adrian Onu

Institutul Cantacuzino — Romania

Medicine · Health Sciences

15h-index780citations44works3.72yr avg
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Research Topics

Monoclonal and Polyclonal Antibodies Research(8), Transgenic Plants and Applications(8), Influenza Virus Research Studies(7), Viral gastroenteritis research and epidemiology(6), Viral Infectious Diseases and Gene Expression in Insects(6)

Publications44 total

Red Alga <i>Porphyridium</i> Supports High‐Yield Production of a Functional Chimeric Hepatitis B Surface Antigen With Strong Cellular and Humoral Immunogenicity
Plant Biotechnology Journal·2025Open Access
Humanized mouse model reveals the immunogenicity of Hepatitis B Virus vaccine candidates produced in CRISPR/Cas9-edited Nicotiana benthamiana
Frontiers in Immunology·2025· 1 citedOpen Access
The red alga <i>Porphyridium</i> as a host for molecular farming: Efficient production of immunologically active hepatitis C virus glycoprotein
Proceedings of the National Academy of Sciences·2024· 10 citedOpen Access
Generation of a DSF-Guided Refolded Bacterially Expressed Hemagglutinin Ectodomain of Influenza Virus A/Puerto Rico/8/1934 H1N1 as a Model for Influenza Vaccine Antigens
Vaccines·2023· 2 citedOpen Access
The “humanized” N‐glycosylation pathway in <scp>CRISPR</scp>/Cas9‐edited <i>Nicotiana benthamiana</i> significantly enhances the immunogenicity of a S/<scp>preS1</scp> Hepatitis B Virus antigen and the virus‐neutralizing antibody response in vaccinated mice
Plant Biotechnology Journal·2023· 18 citedOpen Access
Comparison of truncated human angiotensin-converting enzyme 2 (hACE2) expression in pET28a(+) versus pET-SUMO vector and two Escherichia coli strains
Advances in Medical Sciences·2023· 5 cited
Efficient cellular and humoral immune response and production of virus-neutralizing antibodies by the Hepatitis B Virus S/preS116-42 antigen
Frontiers in Immunology·2022· 12 citedOpen Access
Hepatitis C virus E2 envelope glycoprotein produced in <i>Nicotiana benthamiana</i> triggers humoral response with virus‐neutralizing activity in vaccinated mice
Plant Biotechnology Journal·2021· 15 citedOpen Access
The Application of Single Use Bioreactors for the Production of a Carotenoids Mix, Mainly Torularhodin
Revista de Chimie·2019· 1 citedOpen Access
Oral administration of a chimeric Hepatitis B Virus S/preS1 antigen produced in lettuce triggers infection neutralizing antibodies in mice
Vaccine·2018· 19 cited
Nutritional and Anti-nutritional Analysis of Monechma ciliatum Leaves
Research Journal of Food Science and Nutrition·2018· 4 citedOpen Access
A novel chimeric Hepatitis B virus S/preS1 antigen produced in mammalian and plant cells elicits stronger humoral and cellular immune response than the standard vaccine-constituent, S protein
Antiviral Research·2017· 23 cited
Lettuce‐produced hepatitis C virus E1E2 heterodimer triggers immune responses in mice and antibody production after oral vaccination
Plant Biotechnology Journal·2017· 63 citedOpen Access
Influenza Vaccine Manufacturing: Effect of Inactivation, Splitting and Site of Manufacturing. Comparison of Influenza Vaccine Production Processes
PLoS ONE·2016· 80 citedOpen Access
Technology transfer of oil-in-water emulsion adjuvant manufacturing for pandemic influenza vaccine production in Romania: Preclinical evaluation of split virion inactivated H5N1 vaccine with adjuvant
Human Vaccines & Immunotherapeutics·2015· 14 citedOpen Access
Adenylate cyclases involvement in pathogenicity, a minireview.
PubMed·2013· 6 cited
Technology transfer of oil-in-water emulsion adjuvant manufacturing for pandemic influenza vaccine production in Romania
Vaccine·2012· 24 citedOpen Access
Survival of H5N1 influenza virus in water and its inactivation by chemical methods.
PubMed·2011· 13 cited
Therapeutic Product Preparation Bioprocess Modeling
2010· 2 citedOpen Access
Evaluation of the efficacy of a specific hyperimmune serum in experimental influenza infection in mice.
PubMed·2010· 2 cited
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Frequent Co-authors

Iuliana Caraș(11), Cătălin Ţucureanu(11), Crina Stăvaru(11), M Stefănescu(11), G Szégli(10), Norica Branza‐Nichita(9), Jihong Liu Clarke(8), Armin Distler(7), Silvia Bulfone‐Paus(6), Mihaela‐Olivia Dobrica(6), Cristiana Matache(6), Irina Ionescu(6), Adriana Costache(6), Thomas Pohl(5), Hans Krause(5), Emilia Lupulescu(5), André van Eerde(5), Hege Steen(5), Sissel Haugslien(5), Catalin Lazar(5)