Alec I. McKenzie

University of Utah — United States

Medicine · Health Sciences

19h-index879citations49works0.02yr avg
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Research Topics

Nutrition and Health in Aging(16), Muscle Physiology and Disorders(13), Exercise and Physiological Responses(11), Adipose Tissue and Metabolism(9), Muscle metabolism and nutrition(8)

Publications49 total

Differential Effects of PB125 and MitoQ Supplementation and Limb Immobilization on Mitochondrial Respiration and Protein Expression in Skeletal Muscle
Physiology·2025
Metformin Blunts Bed Rest-induced Skeletal Muscle Ceramide Accumulation in Older Adults
Physiology·2024
Targeted activation of Nrf2 prevents losses in leg muscle mass and strength during 2 weeks of immobilization in young adults
Physiology·2024
Disuse‐induced muscle fibrosis, cellular senescence, and senescence‐associated secretory phenotype in older adults are alleviated during re‐ambulation with metformin pre‐treatment
Aging Cell·2023· 47 citedOpen Access
Two Weeks of Nrf2 Activation Improves Maximal Mitochondrial Respiration in Older Adults with Lower Starting Values
Physiology·2023
Pharmacological modulation of adrenergic tone alters the vasodilatory response to passive leg movement in young but not in old adults
Journal of Applied Physiology·2023· 4 citedOpen Access
Global deletion of CCL2 has adverse impacts on recovery of skeletal muscle fiber size and function and is muscle specific
Journal of Applied Physiology·2023· 11 citedOpen Access
Muscle disuse as hindlimb unloading in early postnatal mice negatively impacts grip strength in adult mice: a pilot study
Journal of Applied Physiology·2023· 5 citedOpen Access
Reply to Horn et al.
Journal of Applied Physiology·2022Open Access
Targeting Endogenous Antioxidant Capacity to Prevent Vascular Dysfunction Induced by Limb Immobilization
The FASEB Journal·2022
Short-term exposure to a clinical dose of metformin increases skeletal muscle mitochondrial H2O2 emission and production in healthy, older adults: A randomized controlled trial
Experimental Gerontology·2022· 12 citedOpen Access
Cardiovasomobility: an integrative understanding of how disuse impacts cardiovascular and skeletal muscle health
Journal of Applied Physiology·2022· 16 citedOpen Access
Metformin and leucine increase satellite cells and collagen remodeling during disuse and recovery in aged muscle
The FASEB Journal·2021· 33 citedOpen Access
Impact of presymptomatic COVID-19 on vascular and skeletal muscle function: a case study
Journal of Applied Physiology·2021· 25 citedOpen Access
Reduced Physical Activity Alters the Leucine-Stimulated Translatome in Aged Skeletal Muscle
The Journals of Gerontology Series A·2021· 11 citedOpen Access
Acute Effects of Cheddar Cheese Consumption on Circulating Amino Acids and Human Skeletal Muscle
Nutrients·2021· 21 citedOpen Access
Short-term metformin ingestion by healthy older adults improves myoblast function
American Journal of Physiology-Cell Physiology·2021· 8 citedOpen Access
Early Life Muscle Disuse Causes Premature Dynapenia In Adulthood
Medicine & Science in Sports & Exercise·2020
Impaired Recovery From Muscle Disuse In Early Life Compared To Young And Mature Adulthood
Medicine & Science in Sports & Exercise·2020
Neuromuscular electrical stimulation and protein during bed rest increases CD11b<sup>+</sup> skeletal muscle macrophages but does not correspond to muscle size or insulin sensitivity
Applied Physiology Nutrition and Metabolism·2020· 14 citedOpen Access
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Frequent Co-authors

Micah J. Drummond(29), Paul T. Reidy(23), Ziad S. Mahmassani(22), Jonathan J. Petrocelli(17), Naomi M. M. P. de Hart(10), Joel D. Trinity(8), Caitlin C. Fermoyle(8), Robin L. Marcus(7), Dennis K. Fix(7), Mark A. Supiano(6), Katsuhiko Funai(6), Jesse C. Craig(6), Russell S. Richardson(6), Michael Howard(5), Nikol M. Yonemura(5), Matthew T. Rondina(5), Patrick J. Ferrara(5), Paul C. LaStayo(4), Scott A. Summers(4), Matthew T. Lewis(4)