José M.P. Freije

Universidad de Oviedo — Spain

Biochemistry, Genetics and Molecular Biology · Life Sciences

55h-index14.2kcitations121works15.82yr avg
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Research Topics

Nuclear Structure and Function(28), RNA Research and Splicing(22), Ubiquitin and proteasome pathways(18), Protease and Inhibitor Mechanisms(16), Peptidase Inhibition and Analysis(16)

Publications121 total

Current advances and future prospects of cell reprogramming in progeroid syndromes
Frontiers in Cell and Developmental Biology·2025Open Access
Loss of ADAM29 does not affect viability and fertility in mice but improves wound healing
iScience·2024· 1 citedOpen Access
Noncoding RNA Contribution to Aging and Lifespan
The Journals of Gerontology Series A·2024· 9 citedOpen Access
The hallmarks of aging as a conceptual framework for health and longevity research
Frontiers in Aging·2024· 53 citedOpen Access
Assessing microbiota composition in the context of aging
Methods in cell biology·2023
USP49 deubiquitinase regulates the mitotic spindle checkpoint and prevents aneuploidy
Cell Death and Disease·2023· 1 citedOpen Access
Autophagy‐linked plasma and lysosomal membrane protein <scp>PLAC8</scp> is a key host factor for <scp>SARS‐CoV</scp> ‐2 entry into human cells
The EMBO Journal·2022· 35 citedOpen Access
Characterization of primary and immortalized whale Müller Glial cells
Acta Ophthalmologica·2022
Contributors
Elsevier eBooks·2020
Ubiquitin-specific proteases as targets for anticancer drug therapies
Elsevier eBooks·2020· 3 cited
Healthspan and lifespan extension by fecal microbiota transplantation into progeroid mice
Nature Medicine·2019· 622 citedOpen Access
Development of a CRISPR/Cas9-based therapy for Hutchinson–Gilford progeria syndrome
Nature Medicine·2019· 171 citedOpen Access
Retraction Note: NF-κB activation impairs somatic cell reprogramming in ageing
Nature Cell Biology·2018· 2 citedOpen Access
The microRNA-29/PGC1α regulatory axis is critical for metabolic control of cardiac function
PLoS Biology·2018· 67 citedOpen Access
Methionine Restriction Extends Lifespan in Progeroid Mice and Alters Lipid and Bile Acid Metabolism
Cell Reports·2018· 181 citedOpen Access
Matrix metalloproteinase Mmp-1a is dispensable for normal growth and fertility in mice and promotes lung cancer progression by modulating inflammatory responses.
Journal of Biological Chemistry·2018· 7 citedOpen Access
Matrix metalloproteinase Mmp-1a is dispensable for normal growth and fertility in mice and promotes lung cancer progression by modulating inflammatory responses (vol. 288, pg 1467, 2013). Corrección
Journal of Biological Chemistry·2018
Protease Silencing to Explore the Molecular Mechanisms of Cancer and Aging
Methods in molecular biology·2018Open Access
Loss of the deubiquitinase USP36 destabilizes the RNA helicase DHX33 and causes preimplantation lethality in mice
Journal of Biological Chemistry·2017· 68 citedOpen Access
Deubiquitination in cancer stem cells
Aging·2017· 3 citedOpen Access
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Frequent Co-authors

Carlos López-Otı́n(44), Juan Cadiñanos(11), Fernando G. Osorio(11), Alberto M. Pendás(9), Milagros Balbı́n(8), Francisco Rodríguez(8), Ignacio Varela(7), Alejandro P. Ugalde(7), Guillermo Mariño(7), Vı́ctor Quesada(6), Gloria Velasco(6), Antonio Fueyo(6), Xosé S. Puente(5), Pedro M. Quirós(5), Nicolas Lévy(5), Ana Gutiérrez‐Fernández(4), Marta Gut(4), Luis Sánchez‐Pulido(4), Guido Kroemer(4), Clea Bárcena(4)