E. Eigenbrodt

University of Giessen — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

40h-index5.3kcitations112works0.02yr avg
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Research Topics

Cancer, Hypoxia, and Metabolism(41), Metabolism, Diabetes, and Cancer(21), Amino Acid Enzymes and Metabolism(21), Pancreatic function and diabetes(9), Biochemical and Molecular Research(9)

Publications112 total

Isotype‐specific inhibitors of the glycolytic key regulator pyruvate kinase subtype M2 moderately decelerate tumor cell proliferation
International Journal of Cancer·2008· 80 citedOpen Access
Premature senescence of human endothelial cells induced by inhibition of glutaminase
Biogerontology·2008· 103 cited
Regulation of pyruvate kinase type M2 by A-Raf: a possible glycolytic stop or go mechanism.
PubMed·2008· 51 cited
From Target to Lead Synthesis
Methods and principles in medicinal chemistry·2006· 3 cited
Pyruvate kinase type M2 and its role in tumor growth and spreading
Seminars in Cancer Biology·2005· 822 cited
Faecal tumour M2 pyruvate kinase: a new, sensitive screening tool for colorectal cancer
British Journal of Cancer·2004· 138 citedOpen Access
Phosphoglycerate Mutase-derived Polypeptide Inhibits Glycolytic Flux and Induces Cell Growth Arrest in Tumor Cell Lines
Journal of Biological Chemistry·2004· 60 citedOpen Access
Value of tumor M2-PK in thyroid carcinoma: a pilot study.
PubMed·2004· 3 cited
Metabolic analysis of senescent human fibroblasts reveals a role for AMP in cellular senescence
Biochemical Journal·2003· 249 citedOpen Access
The tumor metabolome.
PubMed·2003· 137 cited
Fuzzy logic-based tumor marker profiles including a new marker tumor M2-PK improved sensitivity to the detection of progression in lung cancer patients.
PubMed·2003· 33 cited
Tumor M2-pyruvate kinase in the follow-up of inoperable lung cancer patients: a pilot study
Cancer Letters·2003· 36 cited
Interaction between HERC1 and M2‐type pyruvate kinase
FEBS Letters·2003· 37 cited
Fuzzy logic-based tumor marker profiles improved sensitivity of the detection of progression in small-cell lung cancer patients
Clinical and Experimental Medicine·2003· 24 cited
Tumor M2-pyruvate kinase in lung cancer patients: immunohistochemical detection and disease monitoring.
PubMed·2002· 77 cited
[Brain emboli in the lungs of cattle].
PubMed·2002· 6 cited
Fuzzy logic-based tumor-marker profiles improved sensitivity in the diagnosis of lung cancer
International Journal of Clinical Oncology·2002· 57 cited
Pyruvate kinase type M2: a crossroad in the tumor metabolome
British Journal Of Nutrition·2002· 161 citedOpen Access
Regulation of glycolysis by Raf protein serine/threonine kinases
Advances in Enzyme Regulation·2002· 46 cited
Regulatory potential of<i>n</i>-3 fatty acids in immunological and inflammatory processes
British Journal Of Nutrition·2002· 141 citedOpen Access
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Frequent Co-authors

Sybille Mazurek(16), S. Mazurek(10), Werner Zwerschke(7), Pidder Jansen‐Dürr(7), Joachim Schneider(6), H. G. Velcovsky(5), H Morr(5), Robert R. Friis(4), H. Grimm(4), Peter Presek(4), Kathleen Neu(4), G Weisse(4), C. B. Boschek(3), F Hugo(3), M. Reinacher(3), Hartmut Glossmann(3), Klaus Failing(3), Wilhelm Schoner(3), Eveline Hütter(2), Peter Vaupel(2)