J. Julian Blow

University of East Anglia — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

73h-index17.4kcitations201works0.02yr avg
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Research Topics

DNA Repair Mechanisms(142), Genomics and Chromatin Dynamics(78), Microtubule and mitosis dynamics(64), Epigenetics and DNA Methylation(44), DNA and Nucleic Acid Chemistry(15)

Publications201 total

Geminin inhibits DNA replication licensing by sterically blocking CDT1-MCM2 interactions
Nature Communications·2025Open Access
Correction to “Development of BromoTag: A “Bump-and-Hole”–PROTAC System To Induce Potent, Rapid, and Selective Degradation of Tagged Target Proteins”
Journal of Medicinal Chemistry·2025Open Access
The Atad5 RFC-like complex is the major unloader of proliferating cell nuclear antigen in Xenopus egg extracts
Journal of Biological Chemistry·2023· 3 citedOpen Access
The Atad5 RFC-like complex is the major unloader of proliferating cell nuclear antigen in <i>Xenopus</i> egg extracts
2023Open Access
The location and development of Replicon Cluster Domains in early replicating DNA
Wellcome Open Research·2023· 5 citedOpen Access
The location and development of Replicon Cluster Domains in early replicating DNA
Wellcome Open Research·2023· 4 citedOpen Access
Author Correction: Dynamic SUMO modification regulates mitotic chromosome assembly and cell cycle progression in Caenorhabditis elegans
Nature Communications·2022· 1 citedOpen Access
DDK: The Outsourced Kinase of Chromosome Maintenance
Biology·2022· 13 citedOpen Access
Review of: "Determination of human DNA replication origin position and efficiency reveals principles of initiation zone organisation"
2022Open Access
Development of BromoTag: A “Bump-and-Hole”–PROTAC System to Induce Potent, Rapid, and Selective Degradation of Tagged Target Proteins
Journal of Medicinal Chemistry·2021· 103 citedOpen Access
High levels of origin licensing during <i>Xenopus</i> cleavage divisions ensures complete and timely genome duplication
2021Open Access
The role of DDK and Treslin–MTBP in coordinating replication licensing and pre-initiation complex formation
Open Biology·2021· 28 citedOpen Access
The role of DDK and Treslin-MTBP in coordinating replication licensing and pre-Initiation Complex formation
2021· 1 citedOpen Access
3 tera-basepairs as a fundamental limit for robust DNA replication
Physical Biology·2020· 3 citedOpen Access
Defects in the origin licensing checkpoint stresses cells exiting G0
The Journal of Cell Biology·2019· 8 citedOpen Access
Histone H4K20 methylation mediated chromatin compaction threshold ensures genome integrity by limiting DNA replication licensing
Nature Communications·2018· 96 citedOpen Access
A histone H4K20 methylation-mediated chromatin compaction threshold ensures genome integrity by limiting DNA replication licensing
2018Open Access
Lgr5+ intestinal stem cells reside in an unlicensed G1 phase
The Journal of Cell Biology·2018· 63 citedOpen Access
Replication Licensing System
2018· 3 cited
Replication Licensing System
2017· 3 cited
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Frequent Co-authors

J. Chong(6), Ronald A. Laskey(5), Peter J. Gillespie(5), Dean A. Jackson(4), Anatoliy Li(4), Tim Hunt(4), Hiro Mahbubani(3), Alison Rowles(3), Michael Howell(3), Pia Thömmes(3), Ulrich Strausfeld(3), Laurent Meijer(2), Paul Nurse(2), Shusuke Tada(2), Jeremy Minshull(2), Maren Oehlmann(2), Emma J. Haagensen(2), Vassilis G. Gorgoulis(2), Anthony D. Mills(2), Xin Quan Ge(2)