Joanna M. Day

Vanderbilt University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

18h-index1.1kcitations49works0.02yr avg
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Research Topics

Estrogen and related hormone effects(24), Hormonal Regulation and Hypertension(10), Pharmacogenetics and Drug Metabolism(7), Cancer Treatment and Pharmacology(7), Crystallization and Solubility Studies(5)

Publications49 total

Evaluating the impact of immune checkpoint inhibitors on liver steatosis and function: a retrospective cohort analysis
Frontiers in Oncology·2025Open Access
CCDC 2088971: Experimental Crystal Structure Determination
The Cambridge Structural Database·2022Open Access
Substituted Aryl Benzylamines as Potent and Selective Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 3
Molecules·2021· 2 citedOpen Access
In vivo and in vitro properties of STX2484: a novel non-steroidal anti-cancer compound active in taxane-resistant breast cancer
British Journal of Cancer·2014· 13 citedOpen Access
STX140, but Not Paclitaxel, Inhibits Mammary Tumour Initiation and Progression in C3(1)/SV40 T/t-Antigen Transgenic Mice
PLoS ONE·2013· 22 citedOpen Access
STX2171, a 17β-hydroxysteroid dehydrogenase type 3 inhibitor, is efficacious in vivo in a novel hormone-dependent prostate cancer model
Endocrine Related Cancer·2012· 17 citedOpen Access
Overexpression of 17β-Hydroxysteroid Dehydrogenase Type 1 Increases the Exposure of Endometrial Cancer to 17β-Estradiol
The Journal of Clinical Endocrinology & Metabolism·2012· 64 citedOpen Access
The effects of paclitaxel and STX140 on early-and late-stage breast cancer in tte clinically relevant C3(1)/SV40 mouse model
European Journal of Cancer·2011
Order within disorder: Aggrecan chondroitin sulphate‐attachment region provides new structural insights into protein sequences classified as disordered
Proteins Structure Function and Bioinformatics·2010· 14 citedOpen Access
Order in Disorder: Aggrecan CS Region Predicts a New Class of Protein Structure
The FASEB Journal·2010
Abstract 4413: STX140 is an orally bioavailable microtubule targeting agent with no associated peripheral neuropathy and potent anti-metastasis efficacy in vivo
Cancer Research·2010
Abstract 1558: STX140 but not paclitaxel inhibits mammary tumor initiation, progression and metastasis in C3(1)/SV40 T/t-antigen transgenic mice
Cancer Research·2010
STX2171, a 17 beta-Hydroxysteroid Dehydrogenase Type 3 (17 beta-HSD3) Inhibitor, Is Efficacious In Vivo in a Novel Hormone-Dependent Prostate Cancer Model.
Endocrine Reviews·2010
The Development of Steroid Sulfatase Inhibitors for Hormone‐Dependent Cancer Therapy
Annals of the New York Academy of Sciences·2009· 38 cited
BCRP expression does not result in resistance to STX140 in vivo, despite the increased expression of BCRP in A2780 cells in vitro after long-term STX140 exposure
British Journal of Cancer·2009· 20 citedOpen Access
Development of hormone-dependent prostate cancer models for the evaluation of inhibitors of 17β-hydroxysteroid dehydrogenase Type 3
Molecular and Cellular Endocrinology·2008· 17 citedOpen Access
The design of novel 17β-hydroxysteroid dehydrogenase type 3 inhibitors
Molecular and Cellular Endocrinology·2008· 28 citedOpen Access
Design and validation of specific inhibitors of 17 -hydroxysteroid dehydrogenases for therapeutic application in breast and prostate cancer, and in endometriosis
Endocrine Related Cancer·2008· 121 citedOpen Access
Novel inhibitors of 17β-hydroxysteroid dehydrogenase type 1: Templates for design
Bioorganic & Medicinal Chemistry·2008· 40 citedOpen Access
STX140 Is Efficacious <i>In vitro</i> and <i>In vivo</i> in Taxane-Resistant Breast Carcinoma Cells
Clinical Cancer Research·2008· 45 cited
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Frequent Co-authors

Michael Reed(26), Helena J. Tutill(22), Atul Purohit(21), Barry V. L. Potter(18), Nigel Vicker(17), Paul Foster(13), Mathew P. Leese(12), Harshani R. Lawrence(11), Simon P. Newman(10), G.M. Allan(9), Stephen T. Newman(9), B. V. L. POTTER(9), A. Purohit(8), Christian Bubert(6), A. Purohit(6), Surinder K. Chander(5), Delphine S. Fischer(5), Bindumalini Raobaikady(5), Philip G. Kasprzyk(5), Alan D. Murdoch(4)