Lachlan Whitehead

Walter and Eliza Hall Institute of Medical Research — Australia

Medicine · Health Sciences

34h-index5.9kcitations141works3.42yr avg
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Research Topics

Cytokine Signaling Pathways and Interactions(17), Cell death mechanisms and regulation(12), Cancer Mechanisms and Therapy(12), Cell Image Analysis Techniques(10), interferon and immune responses(9)

Publications141 total

napari-lattice
Zenodo (CERN European Organization for Nuclear Research)·2026Open Access
Non-apoptotic caspase-8 is critical for orchestrating exaggerated inflammation during severe SARS-CoV-2 infection
Nature Communications·2025Open Access
LeGO-3D: 3D imaging of lung metastases and vascularisation using light sheet fluorescence microscopy
npj Imaging·2025Open Access
Differentiation of <i>Toxoplasma</i> into latent forms is linked to central carbon metabolism and requires a GID/CTLH-type E3 ubiquitin ligase
2025· 1 citedOpen Access
LeGO-3D: 3D imaging of lung metastases and vascularisation using light sheet fluorescence microscopy
2025Open Access
Inhibition of the minor spliceosome restricts the growth of a broad spectrum of cancers
EMBO Reports·2025· 3 citedOpen Access
Su1887: CELL DEATH DYSREGULATION IS A MOLECULAR HALLMARK OF INFLAMMATORY BOWEL DISEASE (IBD)
Gastroenterology·2025
Datasets for napari-lattice: Lattice Lightsheet Analysis
Zenodo (CERN European Organization for Nuclear Research)·2025Open Access
KAT6B overexpression in mice causes aggression, anxiety, and epilepsy
iScience·2025· 1 citedOpen Access
Convolutional neural networks for accurate real-time diagnosis of oral epithelial dysplasia and oral squamous cell carcinoma using high-resolution in vivo confocal microscopy
Scientific Reports·2025· 8 citedOpen Access
Loss of KAT6B causes premature ossification and promotes osteoblast differentiation during development
Developmental Biology·2025· 2 cited
Leveraging the Rich Spatiotemporal Features of Lattice Light-sheet Microscopy with Machine Learning and AI
2025Open Access
DOP109 A necroptotic-to-apoptotic signaling axis underlies inflammatory bowel disease
Journal of Crohn s and Colitis·2025Open Access
Specialised Engineering and Optimisation in High-Powered Student Competition Rocketry
2025
Self-maintenance of zonal hepatocytes during adult homeostasis and their complex plasticity upon distinct liver injuries
Cell Reports·2024· 4 citedOpen Access
A necroptotic-to-apoptotic signaling axis underlies inflammatory bowel disease
2024· 5 citedOpen Access
Divergent roles of RIPK3 and MLKL in high-fat diet–induced obesity and MAFLD in mice
Life Science Alliance·2024· 11 citedOpen Access
Loss of PHF6 causes spontaneous seizures, enlarged brain ventricles and altered transcription in the cortex of a mouse model of the Börjeson–Forssman–Lehmann intellectual disability syndrome
PLoS Genetics·2024· 1 citedOpen Access
Supplementary Figures from &lt;i&gt;MACROD2&lt;/i&gt; Haploinsufficiency Impairs Catalytic Activity of PARP1 and Promotes Chromosome Instability and Growth of Intestinal Tumors
2024Open Access
An immunohistochemical atlas of necroptotic pathway expression
EMBO Molecular Medicine·2024· 29 citedOpen Access
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Frequent Co-authors

Kelly L. Rogers(16), Gordon K. Smyth(8), Andreas Strasser(6), James M. Murphy(5), Alan F. Cowman(5), Matthias Ernst(5), Niall D. Geoghegan(4), Grant Dewson(4), Guillaume Lessène(4), Bhupinder Pal(4), Jane E. Visvader(4), Geoffrey J. Lindeman(4), Anne K. Voss(4), Garth J. Williams(4), Harry M. Quiney(4), K. Nugent(4), Andrew G. Peele(4), Marc Pellegrini(4), Ashleigh R. Poh(4), Benjamin T. Kile(3)