Covadonga Pañeda

Biochemistry, Genetics and Molecular Biology · Life Sciences

18h-index1.2kcitations37works2.02yr avg
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Research Topics

RNA Interference and Gene Delivery(9), Ocular Surface and Contact Lens(6), Advanced biosensing and bioanalysis techniques(5), Regulation of Appetite and Obesity(5), Corneal Surgery and Treatments(5)

Publications37 total

Engineered Neuromedin U Promotes Type 2 Innate Immunity and Renoprotection in Acute Kidney Injury
Journal of the American Society of Nephrology·2025· 2 cited
Tivanisiran, a new treatment for Dry Eye Disease, that improved signs and symptoms in clinical trials
Investigative Ophthalmology & Visual Science·2018Open Access
Topical administration of siRNA targeting NRARP as a new treatment for choroidal neovascularization
Investigative Ophthalmology & Visual Science·2018Open Access
Clinical and preclinical study correlation for SYL1001, a new treatment for dry eye disease
Investigative Ophthalmology & Visual Science·2017Open Access
Efficacy of SYL1001 in different animal models of Dry Eye Disease
Investigative Ophthalmology & Visual Science·2017Open Access
Synthetic nanocarriers for the delivery of polynucleotides to the eye
European Journal of Pharmaceutical Sciences·2017· 20 citedOpen Access
Managing Intraocular Pressure: Innovation in Glaucoma Management
InTech eBooks·2016· 4 citedOpen Access
Safety and Efficacy Clinical Trials for SYL1001, a Novel Short Interfering RNA for the Treatment of Dry Eye Disease
Investigative Ophthalmology & Visual Science·2016· 97 citedOpen Access
Results of clinical trials with a novel RNA-based therapy (SYL1001) to treat patients with ocular pain associated to dry eye disease
Investigative Ophthalmology & Visual Science·2016· 1 citedOpen Access
Preclinical Development of RNAi-Inducing Oligonucleotide Therapeutics for Eye Diseases
InTech eBooks·2016· 2 citedOpen Access
Short-interference RNAs: becoming medicines
PubMed·2015· 21 citedOpen Access
Pharmacokinetic and Biosdistribution of Bamosiran in Human and Animal model, a Novel Treatment for Glaucoma
Investigative Ophthalmology & Visual Science·2015· 1 cited
Development of a RNAi therapeutic for the treatment of allergic conjunctivitis
Investigative Ophthalmology & Visual Science·2015· 3 cited
SYL1001, a new treatment based on RNAi for the treatment of ocular pain.
Investigative Ophthalmology & Visual Science·2014· 1 cited
Differential expression and localization of transient receptor potential vanilloid 1 in rabbit and human eyes.
PubMed·2013· 48 citedOpen Access
Phase I Clinical Trial of SYL040012, a Small Interfering RNA Targeting β-Adrenergic Receptor 2, for Lowering Intraocular Pressure
Molecular Therapy·2013· 75 citedOpen Access
In Vitro and In Vivo Efficacy of SYL040012, a Novel siRNA Compound for Treatment of Glaucoma
Molecular Therapy·2013· 111 citedOpen Access
SYL040012, a siRNA for the treatment of glaucoma
Acta Ophthalmologica·2013· 5 cited
Silencing human genetic diseases with oligonucleotide-based therapies
Human Genetics·2013· 49 cited
Transient Receptor Potential Vallinoid 1 Expression and Localization In Rabbit and Human Eye
Investigative Ophthalmology & Visual Science·2012
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Frequent Co-authors

Tamara Martı́nez(13), Verónica Ruz(9), Ana I. Jiménez(8), Isabel Varela‐Nieto(8), Victoria González(8), Laura M. Frago(7), Julie A. Chowen(6), Ana Isabel Jiménez(6), Jesús Argente(5), Beatriz Vargas(5), Javier Moreno‐Montañés(4), Marı́a Victoria González(3), Natalia Wright(3), Belén Sádaba(3), Ana I. Arroba(3), Carmen Martínez‐García(3), Ana V. Villar(3), Alicia Alonso(3), Urs Brodbeck(3), Félix M. Goñi(3)